Pediatric Admissions During the COVID-19 Pandemic in a Hospital with Low Prevalence of SARS-CoV-2

Pediatric Admissions During the COVID-19 Pandemic in a Hospital with Low Prevalence of SARS-CoV-2 | Authorea try { document.documentElement.classList.add('js'); } catch (e) { } var _gaq = _gaq || []; _gaq.push(['_setAccount', 'G-8VDV14Y67G']); _gaq.push(['_trackPageview']); (function() { var ga = document.createElement('script'); ga.type = 'text/javascript'; ga.async = true; ga.src = ('https:' == document.location.protocol ? 'https://ssl' : 'http://www') + '.google-analytics.com/ga.js'; var s = document.getElementsByTagName('script')[0]; s.parentNode.insertBefore(ga, s); })(); Skip to main content Preprints Collections Wiley Open Research IET Open Research Ecological Society of Japan All Collections About About Authorea FAQs Contact Us Quick Search anywhere Search for preprint articles, keywords, etc. Search Search ADVANCED SEARCH SCROLL This is a preprint and has not been peer reviewed. Data may be preliminary. 23 July 2025 V1 Latest version Share on Pediatric Admissions During the COVID-19 Pandemic in a Hospital with Low Prevalence of SARS-CoV-2 Authors : Jordon C. Mitzelfelt 0009-0004-1753-8058 [email protected] , Kristin C. Mara , Jaclyn Whelan , Patrick Wieneke , David J. Hall , Matthew C. Authement , Erin E. Knoebel , Travis R. Kirkpatrick , Michael E. Nemergut , and Yu Kawai 0000-0002-5452-0867 Authors Info & Affiliations https://doi.org/10.22541/au.175327205.54018587/v1 Published APMIS Version of record Peer review timeline 425 views 185 downloads Contents Abstract Supplementary Material Information & Authors Metrics & Citations View Options References Figures Tables Media Share Abstract Background : The COVID-19 pandemic profoundly impacted healthcare, emphasizing the need to strengthen future pandemic responses and optimize resource allocation planning and deployment during times of disruption and crisis. Methods : This retrospective, single-center, cross-sectional study included participants ≤17 years-old admitted to the Children’s Hospital (CH) between 01/01/2017 and 12/31/2021. Clinical data was abstracted using Vizient ® Clinical Data Base and the internal data warehouse. Using the International Classification of Disease, 10 th Revision, Clinical Modification (ICD-10-CM) admit diagnosis, frequency and pattern of total admissions during the pre-pandemic phase (2017 Q1-2019 Q4) and intra-pandemic phase (2020 Q1-2021 Q4) were compared. Results : The study included 33,158 admissions. CH SARS-CoV-2 prevalence rate was 0.1% in 2020 and 0.5% in 2021. There was a decrease in overall admissions to the CH (p <0.01) and PICU (p <0.01) at the start of the pandemic. There were significant and variable differences in admission patterns for certain infectious, mental health, and seizure related diagnoses. Seasonality was noted for viral bronchiolitis during the pre-pandemic phase but was disrupted during the intra-pandemic phase with significantly lower admission rates for viral bronchiolitis in 2020 Q4 (p <0.05) and 2021 Q1 (p <0.01), followed by a significant early increase in viral bronchiolitis admissions in 2021 Q3 (p <0.01). Conclusion : The COVID-19 pandemic significantly impacted the number and pattern of admissions despite low SARS-CoV-2 prevalence in our hospital. These changes may be secondary to COVID-19 mitigation strategies implemented in the community. Results can inform anticipated patterns during future pandemics. Supplementary Material File (figures_influenza and other respiratory viruses.doc.docx) Download 1.72 MB File (manuscript_influenza and other respiratory viruses.doc.docx) Download 79.48 KB Information & Authors Information Version history V1 Version 1 23 July 2025 Peer review timeline Published APMIS Version of Record 27 Feb 2026 Published Copyright This work is licensed under a Non Exclusive No Reuse License. Keywords covid-19 epidemiology patient admission pediatrics sars-cov-2 Authors Affiliations Jordon C. Mitzelfelt 0009-0004-1753-8058 [email protected] Mayo Clinic Children's Center View all articles by this author Kristin C. Mara Mayo Clinic Department of Health Sciences Research View all articles by this author Jaclyn Whelan Vizient Inc View all articles by this author Patrick Wieneke Vizient Inc View all articles by this author David J. Hall Mayo Clinic Children's Center View all articles by this author Matthew C. Authement Mayo Clinic Children's Center View all articles by this author Erin E. Knoebel Mayo Clinic Children's Center View all articles by this author Travis R. Kirkpatrick Mayo Clinic Children's Center View all articles by this author Michael E. Nemergut Mayo Clinic Minnesota Department of Anesthesiology and Perioperative Medicine View all articles by this author Yu Kawai 0000-0002-5452-0867 Mayo Clinic Children's View all articles by this author Metrics & Citations Metrics Article Usage 425 views 185 downloads .FvxKWukQNSOunydq8rnd { width: 100px; } Citations Download citation Jordon C. Mitzelfelt, Kristin C. Mara, Jaclyn Whelan, et al. Pediatric Admissions During the COVID-19 Pandemic in a Hospital with Low Prevalence of SARS-CoV-2. Authorea . 23 July 2025. DOI: https://doi.org/10.22541/au.175327205.54018587/v1 If you have the appropriate software installed, you can download article citation data to the citation manager of your choice. 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