Endometrial osseous metaplasia: clinicopathological study of a case and literature review

T. Ramya, T. Chitra, C Poornima, B. Anjana
In: International Journal of Reproduction, Contraception, Obstetrics and Gynecology · 2013 · vol. 2(4) , pp. 719 · doi:10.5455/2320-1770.ijrcog20131251 · W2130732084
article OA: diamond CC0 ⤵ 2 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-07 ⓘ

This case study and literature review examines endometrial osseous metaplasia, a rare condition potentially caused by retained fetal bone or chronic inflammation, presenting a case of a woman with abnormal bleeding post-abortion.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-07 ⓘ

This clinicopathological paper describes a single 41-year-old woman with menorrhagia and dysmenorrhoea who developed endometrial osseous metaplasia after an induced abortion 16 years earlier, and summarizes her management via hysterectomy. The authors also provide a literature review and discuss that the etiology and pathogenesis of endometrial ossification are controversial, with commonly cited hypotheses including retention of fetal bones and transformation of mesenchymal tissue to bone in response to chronic inflammation. A major limitation is that the evidence base is inherently limited to a single case plus a narrative literature review, rather than systematic data. This paper does not explicitly discuss endometriosis or adenomyosis; it was included in the corpus via a keyword match in the upstream search index.

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Abstract

Endometrial ossification is a rare clinical condition related to menstrual disturbances and infertility. Its etiology and pathogenesis are controversial. The commonly accepted hypothesis is that ossification represents retained fetal bones following spontaneous or therapeutic abortion suggesting enchondral ossification. It can also be due to transformation of mesenchymal tissue to bone in response to chronic inflammation. We present one such case in a 41 year old woman who presented with menorrhagia and dysmenorrhoea following induced abortion 16 years back at 12 weeks of gestation. The patient underwent hysterectomy. We also present a literature review.

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Condition tags

dysmenorrheainfertility

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last seen: 2026-06-10T17:14:06.276822+00:00
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