A new BNiLi glass sample [Li2O-B2O3-NiO] conjugated with poly (L-alanine) modified carbon paste electrode for the electrochemical determination of linezolid

A new BNiLi glass sample [Li2O-B2O3-NiO] conjugated with poly (L-alanine) modified carbon paste electrode for the electrochemical determination of linezolid | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Research Article A new BNiLi glass sample [Li2O-B2O3-NiO] conjugated with poly (L-alanine) modified carbon paste electrode for the electrochemical determination of linezolid M. Abd-Elsabour, Mortaga M. Abou-Krisha, Abdulrahman G. Alhamzani, and 3 more This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-4774514/v1 This work is licensed under a CC BY 4.0 License Status: Posted Version 1 posted You are reading this latest preprint version Abstract A new glass sample (BNiLi) was prepared by melt-quenching method. The physical nature of glass sample was investigated via X-ray diffraction, while the atomic structure was studied via density and infrared spectroscopy. The existence of main structure units such as BO3 and BO4 was confirmed. Furthermore, the optical absorbance was measured, and the electronic transitions of nickel ions were revealed. Optical band gap energy was estimated for BNiLi glass sample. The prepared BNiLi glass was used to modify a carbon paste electrode (CPE) with a polymer film of L-alanine (Ala). The obtained p-Ala@BNiLi/CPE was employed to determine Linezolid (LIN) by cyclic voltammetric, linear sweep voltammetric, differential pulse voltammetric and chronoamperometric methods. The proposed sensor achieve a low limit of detection(23 nM), good repeatability and high stability.The fabricated sensor was applied to detect LIN in pharmaceutical and human serum samples. Linezolid Carbon paste electrode BNiLi glass poly (L-alanine) differential pulse voltammetry chronoamperometry Full Text Additional Declarations No competing interests reported. Cite Share Download PDF Status: Posted Version 1 posted You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. Our growing team is made up of researchers and industry professionals working together to solve the most critical problems facing scientific publishing. Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-4774514","acceptedTermsAndConditions":true,"allowDirectSubmit":true,"archivedVersions":[],"articleType":"Research Article","associatedPublications":[],"authors":[{"id":333348865,"identity":"181ea81a-efe4-4e95-b9bd-a5c72e4b2f52","order_by":0,"name":"M. 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The physical nature of glass sample was investigated via X-ray diffraction, while the atomic structure was studied via density and infrared spectroscopy. The existence of main structure units such as BO3 and BO4 was confirmed. Furthermore, the optical absorbance was measured, and the electronic transitions of nickel ions were revealed. Optical band gap energy was estimated for BNiLi glass sample. The prepared BNiLi glass was used to modify a carbon paste electrode (CPE) with a polymer film of L-alanine (Ala). The obtained p-Ala@BNiLi/CPE was employed to determine Linezolid (LIN) by cyclic voltammetric, linear sweep voltammetric, differential pulse voltammetric and chronoamperometric methods. 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