Piperidinyl-thiazole carboxylic acid derivatives as angiogenesis inhibitors
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Piperidinyl-thiazole carboxylic acid derivatives are identified as angiogenesis inhibitors useful for treating VEGF-mediated disorders, specifically endometriosis and acute macular degenerative disorder.
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Abstract
This invention relates to compounds of formula (I) and (II) that are useful in treating vascular endothelial growth factor (VEGF)-mediated disorders, particularly endometriosis and acute macular degenerative disorder. The invention also relates to a topical system for the treatment of acute macular degenerative disorder comprising a VEGF inhibitor.
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- europepmc
- last seen: 2026-07-14T06:08:30.651965+00:00