Effect of uterine artery embolization used in treatment of adenomyosis on ovarian funtion

Objective:To investigate the effects on ovarian function of uterine artery embolization (UAE) for the treatment of adenomyosis and complications of UAE.Methods:UAE was performed in 27 cases with adenomyosis, and the embolic agent was polyvinyl alcohol particles (PVA).The effects of the treatment, levels of sexual hormone were evaluated, and the uterus artery and ovarian artery were examined with transvaginal Color Doppler Energy Sonography (TVCDES) before UAE and the 1st day, 3 months, 6 months after UAE.Results:After 3 months of UAE, the volume of uterus was decreased dramatically by 136.48 cm3(37.6%), Vmax (cm/s) of uterine artery was lower, from(27.27±6.03)cm/s to (14.19±5.98)cm/s,P0.05, RI of uterine artery was increased, form 0.54±0.03 to 0.86±0.04,P0.05; There was no difference in ovarian blood stream, FSH, E2 and menstrual cycle after UAE; One patient had short phase of ovarian function reduction dramatically. Conclusion:UAE for adenomyosis is a new,less-trauma,safe,effective,less-complications and short-time recovery therapy with satisfying midterm effects, which can preserve uterine function and do not damage the function of ovaries,but it may cause ovarian failure.