Clinical factors of reproductive outcome after laparoscopic treatment in patients with endometriosis

Haining Jiao, Zhu Lan, Buchu Wu
In: Zhongguo yishi zazhi · 2018 · vol. 20(12) , pp. 1807–1809 · doi:10.3760/cma.j.issn.1008-1372.2018.12.012 · W3028935781
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This retrospective study analyzed reproductive outcomes in 80 patients with endometriosis-related infertility who underwent laparoscopic surgery between 2010 and 2017. The overall postoperative pregnancy rate was 37.5%, with logistic regression identifying two significant predictors for successful conception. Specifically, the use of postoperative gonadotropin-releasing hormone agonists (GnRH-a) and the adoption of assisted reproductive technologies were strongly correlated with higher pregnancy rates. This paper is centrally about endometriosis — specifically examining clinical factors influencing fertility after surgical treatment of the disease.

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Abstract

Objective To investigate the factors correlated to the pregnancy rate of the patients with endometriosis after laparoscopy. Methods A total of 80 patients with endometriosis related infertile who received laparoscopic surgery in our hospital from January 2010 to January 2017 were enrolled in this study. The postoperative pregnancy of the patients and related factors were analyzed by logistic regression. Results The postoperative pregnancy rate was 37.5% (30/80). Among the pregnancies, 22 cases were ≤12 months, 8 cases >12 months.Logistic regression analysis revealed that postoperative combined medication [gonadotropin-releasing hormone-agonist (GnRH-a)] (OR=19.222, 95% CI: 3.528-104.731, P<0.05) and artificial proconceptive (OR=13.581, 95% CI: 1.913-96.397, P<0.05) are correlated with pregnancy rate after laparoscopic surgery. Conclusions Postoperative combined medication and artificial proconceptive are influencing factors of pregnancy rate after laparoscopy in endometriosis patients with infertile. Key words: Endometriosis/CO/SU; Infertility, female/ET/SU; Laparoscopy; Pregnancy rate
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子宫内膜异位症患者腹腔镜术后生殖预后的影响因素分析 Clinical factors of reproductive outcome after laparoscopic treatment in patients with endometriosis 摘要目的 探讨影响子宫内膜异位症(内异症)不孕患者腹腔镜术后生殖预后的影响因素.方法 回顾性分析2010年1月至2017年1月本院收治的80例子宫内膜异位症合并不孕症患者腹腔镜术后的妊娠情况,并对相关因素进行logistic回归分析.结果 80例患者最终术后妊娠率为37.5％ (30/80),研究显示有8例＞12个月妊娠,22例≤12个月妊娠.另外合并术后规范用药[促性腺激素释放激素类药物(GnRH-a)](OR=19.222,95％ CI:3.528～104.731,P＜0.05)及术后接受辅助生育技术(OR=13.581,95％CI:1.913 ～96.397,P＜0.05)与患者术后妊娠率具有相关性.结论 术后规范用药(GnRH-a)及接受辅助生育技术是子宫内膜异位症合并不孕症患者腹腔镜术后生殖预后的重要影响因素. 更多相关知识 abstractsObjective To investigate the factors correlated to the pregnancy rate of the patients with endometriosis after laparoscopy.Methods A total of 80 patients with endometriosis related infertile who received laparoscopic surgery in our hospital from January 2010 to January 2017 were enrolled in this study.The postoperative pregnancy of the patients and related factors were analyzed by logistic regression.Results The postoperative pregnancy rate was 37.5％ (30/80).Among the pregnancies,22 cases were ≤ 12 months,8 cases ＞ 12 months.Logistic regression analysis revealed that postoperative combined medication [gonadotropin-releasing hormone-agonist (GnRH-a)] (OR =19.222,95％ CI:3.528-104.731,P ＜ 0.05) and artificial proconceptive (OR =13.581,95％ CI:1.913-96.397,P ＜0.05) are correlated with pregnancy rate after laparoscopic surgery.Conclusions Postoperative combined medication and artificial proconceptive are influencing factors of pregnancy rate after laparoscopy in endometriosis patients with infertile. More相关知识 - 浏览0 - 被引26 - 下载0 相似文献 - 中文期刊 - 外文期刊 - 学位论文 - 会议论文

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