Does obese patients benefit from isolated aortic valve replacement through a partial upper sternotomy?

Abstract Objective: Controversial opinions exist for aortic valve replacement(AVR) through partial upper sternotomy in obese patients. Moreover, this study sought to investigate the potential clinical advantage of partial upper sternotomy aortic valve replacement (mini-AVR) over conventional full sternotomy aortic valve replacement (con-AVR) in obese patients.Methods: This was a retrospective and observational study. From January 2015 to December 2020, a total of 184 obese [body mass index (BMI)≥30 kg/m2] patients undergoing isolated primary AVR were included: 98 patients underwent conventional full sternotomy and 86 patients underwent partial upper sternotomy. Propensity score(PS) matching was applied to eliminate the basline imbalances in the mini-AVR and the con-AVR groups.Results: After one-to-one propensity score matching,two groups of 60 patients were obtained.No in-hospital death occurred in the two groups.In addition,cardiopulmonary bypass time and total operative time were similar across the 2 groups, but the aortic cross-clamp time was significantly shorter in the con-AVR group (P = .022). The amount of mediastinal drainage at 48 hours after surgery (P=.018) and postoperative blood transfusions (P=.014) were significantly lower in the mini-AVR group. There was no difference in ventilation time (P=.145), but a shorter intensive care unit stay time (P=.021) in the mini-AVR group.Conclusion: This study demonstrates that aortic valve replacement through a mini-AVR in obese patients is a safe and effective procedure. It outperformed con-AVR in terms of blood loss,blood product transfusion,and ICU stay.