Editorial Expression of Concern: Effect of laser‑assisted zona thinning, during assisted reproduction, on pregnancy outcome in women with endometriosis: randomized controlled trial

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An editorial expression of concern was issued due to concerns about the reliability of P values in a randomized controlled trial on laser-assisted zona thinning and pregnancy outcomes in women with endometriosis.

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This editorial Expression of Concern pertains to a previously published randomized controlled trial evaluating the effect of laser-assisted zona thinning during assisted reproduction on pregnancy outcomes in women with endometriosis. The journal states that concerns were raised about the reliability of P values for numerous variables reported in the trial, and that the authors were unable to provide original data for independent examination. As a result, readers are advised to interpret the results and conclusions with caution, and the note also records that some authors disagreed while others did not respond. Relevance to endometriosis: this editorial specifically concerns an endometriosis-focused randomized controlled trial about laser-assisted zona thinning during assisted reproduction, though its main purpose is to issue an expression of concern about the trial’s evidentiary reliability.

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Vol.:(0123456789)1 3 Archives of Gynecology and Obstetrics (2024) 309:2257 https://doi.org/10.1007/s00404-023-07236-w EDITORIAL EXPRESSION OF CONCERN Editorial Expression of Concern: Effect of laser‑assisted zona thinning, during assisted reproduction, on pregnancy outcome in women with endometriosis: randomized controlled trial Adel Mohamed Nada1 · Amr El‑Noury2 · Hesham Al‑Inany1 · Mamdouh Bibars3 · Tamer Taha3 · Sameh Salama3 · Fatma Hassan3 · Eman Zein4 Published online: 10 October 2023 © Springer-Verlag GmbH Germany, part of Springer Nature 2023 Editorial Expression of Concern: Archives of Gynecol- ogy and Obstetrics (2018) 297:521–528 https://doi.org/10.1007/s00404-017-4604-5 The Editor-in-Chief is issuing an editorial Expression of Concern for this article that reports the outcome of a rand- omized controlled trial. Concerns have been raised about the reliability of the P values for numerous variables reported in this article. The authors have not been able to provide the original data for examination. Readers are therefore advised to interpret the results and conclusions with cau- tion. Amr El-Noury, Hesham Al‐ Inany and Sameh Salama disagree with this statement. Adel Mohamed Nada, Mam- douh Bibars, Tamer Taha, Fatma Hassan and Eman Zein have not responded to correspondence from the Publisher about this statement. Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. The original article can be found online at https:// doi. org/ 10. 1007/ s00404- 017- 4604-5. * Adel Mohamed Nada [email protected] 1 Department of Gynecology and Obstetrics, Faculty of Medicine, Cairo University, 4A/19 Division 3-Zahraa Almaady, Cairo 11555, Egypt 2 Obstetrics and Gynecology, National Laser Institute (NLI), Cairo University, Cairo, Egypt 3 National Research Center (NRC), Cairo, Egypt 4 Department of Gynecology and Obstetrics, Faculty of Medicine, BeniSuif University, Beni Suef, Egypt

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