Editorial Expression of Concern: Effect of laser‑assisted zona thinning, during assisted reproduction, on pregnancy outcome in women with endometriosis: randomized controlled trial
An editorial expression of concern was issued due to concerns about the reliability of P values in a randomized controlled trial on laser-assisted zona thinning and pregnancy outcomes in women with endometriosis.
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This editorial Expression of Concern pertains to a previously published randomized controlled trial evaluating the effect of laser-assisted zona thinning during assisted reproduction on pregnancy outcomes in women with endometriosis. The journal states that concerns were raised about the reliability of P values for numerous variables reported in the trial, and that the authors were unable to provide original data for independent examination. As a result, readers are advised to interpret the results and conclusions with caution, and the note also records that some authors disagreed while others did not respond. Relevance to endometriosis: this editorial specifically concerns an endometriosis-focused randomized controlled trial about laser-assisted zona thinning during assisted reproduction, though its main purpose is to issue an expression of concern about the trial’s evidentiary reliability.
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