HER2-positive Apocrine Carcinoma of the Breast: A population-based Analysis of Treatment and Outcome

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This study explored the clinicopathological features and outcome of HER2+/APO and matched HER2+/NST cohort. Methods We used the SEER database to explore the cohorts. Univariate and multivariate analyses were used to assess the survival. Based on ER and PR [=HR] and HER2 status, we divided the cohorts to match the intrinsic molecular subtypes for comparisons. Results We retrieved 259 cases of HER2+/APO. Most HER2+/APO were HR negative (65%). HER2+/APO were more prevalent in the 80+ age group (24.7% vs. 15.7%, p<0.001). HER2+/HR-/APO had a significantly lower histological grade than the HER2+/HR-/NST (p<0.001). Breast cancer-related deaths were more prevalent in HER2+/NST (7.8% vs. 3.9%, p=0.019). This was particularly evident between HR- subgroups (10.4% in HER2+/HR-/NST vs. 4.2% in HER2+/HR-/APO, p=0.008) and was reaffirmed in breast cancer-specific survival in univariate analysis (p=0.03). Other than race and HR status, HER2+/APO subgroups did not differ in clinicopathological parameters. Conclusions Our study confirms the rarity of the APO and reveals that HR status in APO does not affect these patients' prognosis. HER2+/APO tumors tend to have a less aggressive phenotype and a more favorable outcome despite a markedly lower ER/PR positivity. Breast cancer special types apocrine carcinoma HER2 outcome Figures Figure 1 Figure 2 Figure 3 Figure 4 Introduction Breast carcinoma with apocrine differentiation or apocrine carcinoma (APO) is a rare subtype of invasive breast cancer (~1%) that has a characteristic apocrine morphology along with the androgen receptor (AR) expression and the lack of estrogen receptor (ER) activity [ 3 , 14 , 21 ]. Based on the proposed classification, all APO are either triple-negative (50-70%) or HER2-positive (30-50%) [ 3 , 14 , 18 , 20 – 22 ]. The available clinical data on APO are contradictory due to the rarity of the disease and the use of different diagnostic criteria for APO [ 14 , 19 , 21 ]. Several recent studies have reported a worse clinical outcome in patients with APO than invasive breast carcinoma no special type (IBC NST) [ 4 , 24 ]. However, in an analysis of the Surveillance, Epidemiology, and End Results (SEER) population-based data, the clinical outcome for the APO patients was significantly better than NST patients following the adjustment for demographic and clinicopathological characteristics [ 24 ]. Some studies also revealed more favorable overall survival (OS) and breast cancer-specific survival (BCSS) for patients with AR-positive triple-negative APO compared with other triple-negative breast carcinomas (TNBC) [ 10 – 12 , 25 ]. In contrast, other studies found no significant differences [ 5 , 13 ]. Wu et al. recently reported better clinical outcomes of triple-negative APO patients than TNBC NST [ 23 ]. The authors also found chemotherapy associated with a more favorable outcome among the triple-negative APO patients [ 23 ]. Despite the common HER2 expression, most of the available clinical studies have been focused on the triple-negative APO, while the clinical and survival data on HER2+/APO are sparse [ 7 , 8 ]. The current study explored the association between APO subtypes and survival after adjusting for all other prominent clinical and demographic predictors of survival among SEER patients. Materials And Methods Patients' selection and cohorts We explored the National Cancer Institute’s Surveillance, Epidemiology, and End Results (SEER) database to select our study cohort. The SEER database includes data on patients' demographics, tumor characteristics [Histotype, tumor grade, TNM stage (AJCC), tumor size, lymph node status, and distant metastases], the first course of treatment, treatment options (surgery, chemotherapy, radiotherapy), and follow-up for vital status. It encompasses data from eighteen population-based cancer registries covering approximately 1/3 of the US population. For our study cohort, we selected patients diagnosed with histologically confirmed invasive HER2-positive apocrine carcinoma (APO) (HER2+/APO) between 2010 and 2016. In addition, we selected patients diagnosed with IBC NST with HER2 positivity (HER2+/NST) within the same period. The two groups (HER2+/APO and HER2+/NST) were further divided based on the SEER variable that codes ER and PR [=HR] and HER2 status to form groups based on the intrinsic molecular subtypes, i.e., Apocrine Luminal B (HER2+/HR+/APO) and Apocrine HER2-Enriched (HER2+/HR-/APO) for HER2+/APO and HER2+/HR+/NST and HER2+/HR-/NST for HER2+/NST part of the cohort. HR status did not include androgen receptor. The study excluded in situ carcinomas (both apocrine and NST) and other special types of invasive breast carcinoma with HER2 positivity. We used the SEER*stat version 8.3.2 to generate a case-listing file. Statistical analysis Patients’ demographical and clinicopathological characteristics, including age, hormone receptor status, stage, tumor grade, therapies (surgery, chemotherapy, radiotherapy), regional and distant metastases, as well as metastatic sites, were summarized by absolute and relative frequencies. Age was categorized as 18-49, 50-79, and ≥80 years. The difference in the distribution of clinicopathological characteristics was tested using Pearson chi-square and/or Fisher's exact test, whichever was appropriate according to the expected cell counts. For continuous normally distributed variables, we give mean and standard deviation as measures of central tendency and variability; for those whose distribution is not normal, we give a median and inter-quartile range instead. We tested the equality of means/medians for normally / non-normally distributed variables using the T-test/Mann-Whitney U test. Breast cancer-specific survival (BCSS) and overall survival (OS) were defined as a time in years between the cancer diagnosis and death from breast cancer, death due to any cause, respectively. Patients alive at the end of the follow-up were censored for both types of survival. We ran univariate Cox proportional hazards analysis to identify candidate prognostic factors for the multivariate analysis. For each of these, we produced Kaplan-Meier plots and performed log-rank tests after checking the appropriateness of proportional hazard assumption graphically using martingale and weighted Schoenfeld residuals. After identifying and deciding which prognostic factors will enter the multivariate analyses, we fitted a multivariate Cox regression model to estimate the effect of subtypes on survival while adjusting for other prognostic factors. In the multivariate analysis of BCSS and OS, aside from the HER2+/APO status, we included age (categorical), stage, tumor grade, surgery, and systemic therapies. To provide an additional check of the robustness of our findings w.r.t. modeling assumptions assumed for multivariate Cox regression, we applied propensity score caliper matching in the ratio of 3:1 in favor of the “control” group (HER2+/NST). The propensity score was estimated via a multivariate logistic regression model that included age (in years, continuous), tumor grade, stage, size (in cm), lymph node status, the presence of distant metastasis, chemotherapy and radiation therapy. We applied the same model for propensity score and the same matching strategy for APO vs. NST comparisons (overall, HR+ and HR-) and the analysis for the effect of HR status among the APO subtype. All analyses were performed based on available cases using R Statistical Software (Foundation for Statistical Computing, Vienna, Austria) version 3.5.1. All tests were 2-sided, with p<0.05 considered statistically significant. Results HER2+/APO vs. HER2+/NST cohorts The clinicopathological characteristics of the cohorts are summarized in Table 1 . Among 446,806 breast malignancies diagnosed between 2010 and 2016, there were 259 with HER2+ APO subtype (HER2+/APO) (~0.06%). We also identified 52,860 HER2+ IBC NST (HER2+/NST) in the same period. The median follow-up for the pooled cohort was 31 months (14 = 1st quartile, 53 = 3rd quartile); the median follow up for HER2+/APO was 27 months (12.5 =1st quartile, 48=3rd quartile) and 31 months (14=1st quartile, 53=3rd quartile) for HER2+/NST cohort (p=0.038, Table 1 ). The average age of patients was 69.1 years in the HER2+/APO group and 65.3 years in the HER2+/NST group (p<0.001). HER2+/APO carcinomas were more prevalent in 80+ age group (24.7%, n=64) compared with HER2+/NST cohort (15.7%, n=8283) (p<0.001). HER2+/APO carcinomas had a significantly lower HR (ER and PR) positivity than the HER2+/NST group (p<0.001) (Table 1 ). AR status was not routinely reported in the SEER database. The two groups did not differ significantly regarding the race, tumor stage, regional lymph node status or the presence of distant metastases (in general and in specific sites). The treatment options (surgery and chemotherapy) were similar between HER2+/APO and HER2+/NST (p>0.05), while radiotherapy was more commonly used in the HER2+/APO group compared to HER2+/NST (p=0.05) (Table 1 ). Although at 18 months and onwards, the OS estimate in the HER2+/APO group was consistently higher, with unadjusted HR 1.26 (0.83, 1.92) from the univariate Cox proportional hazards model; however, this difference was not statistically significant (p=0.264) (Figure 1 A). Nevertheless, the positive effect of apocrine morphology was more evident in BCSS analysis with unadjusted HR 1.83 (0.99, 3.42), hence 83% higher hazard for BCSS death in the HER2+/NST group. (Figure 1 B). Breast cancer as a cause of death was also more prevalent in HER2+/NST compared to the HER2+/APO group (7.8% vs. 3.9%, p=0.019). This difference was 1.5 times higher between ER-negative subgroups (4.2% in HER2+/HR-/APO vs. 10.4% in HER2+/HR-/NST, p=0.008). It was reflected in the results of the univariate analysis of BCSS in those groups with unadjusted HR 2.22 (1.06, 4.67) and adjusted (multivariate analysis) HR 2.07 (0.93, 4.62). In a multivariate Cox proportional hazards model analysis, HER2+/APO carcinoma patients had better OS (HR=1.512, CI=0.9-2.32, p=0.059) and significantly better BCSS (HR=2.19, CI 1.13-4.21, p=0.018) compared with HER2+/NST (Table 2 , Figure 2 ). HER2+/HR-/APO vs. HER2+/HR+/APO cohorts The clinicopathological characteristics of the HER2+/APO cohort are summarized in Table 3 . Among the APO tumors, 167 cases were HER2+/HR- (HER2-enriched) (65%), while 91 patients (35%) were HER2+/HR+ (Luminal B) APO carcinomas. HER2+/HR+/APO subtype was more prevalent in the Black race, while HER2+/HR- APO carcinomas were more frequent in other races (neither black nor white) (p=0.022) (Table 3 ). Notably, there was no significant difference between the two APO subgroups regarding the tumor grade, stage, lymph node status, distant metastases in general and specific organs, cause of death, and therapeutic modalities (p>0.05, for all variables) (Table 3 ). The survival curves for two groups defined by HR status (ER and PR) were not significantly different by the log-rank test (Figure 3 ), although their shape was detectable by the log-rank test statistic. This was the case for both OS [HR 0.6 (0.54, 1.57)] and BCSS [HR 0.7 (0.18, 2.74)] in favor of HR-positive status. The patients aged ≥80 years had worse OS in univariate analysis (p<0.001); however, this age-related difference in survival curves completely dissipated when it came to BCSS (p=0.423). HER2+/HR+/APO vs. HER2+/HR+/NST cohorts There were 91 HER2+/HR+/APO (Luminal B) cases and 36556 HER2+/HR+/NST (Luminal B) carcinomas. The mean age in HER2+/HR+/APO was 68.3 years, which was significantly higher than in the HER2+/HR+/NST group (65.2 years, p=0.035). Except for PR, which was less frequent in the HER2+/HR+/APO cohort, the two groups did not differ in clinicopathological parameters, including the treatment modalities. Although in univariate analysis no significant differences were observed, multivariate Cox proportional hazards analysis revealed that the apocrine morphology in HR+/HER2+ carcinomas was associated with better OS (HR=2.62, CI=1.17-5.84, p=0.018) and BCSS (HR=3.14, CI=1.01-9.76, p=0.047) (Table 4). HER2+/HR- APO vs. HER2+/HR- NST cohorts There were 167 cases of HER2+/HR-/APO and 16186 HER2+/HR-/NST carcinomas. At diagnosis, the average age was 69.7 in the HER2+/HR-/APO group vs. 65.6 years in the HER2+/HR-/NST group. HER2+/HR-/APO was more prevalent in older populations than the HER2+/HR-/NST (p=0.001). HER2+/HR-/APO had a significantly lower histological grade than the HER2+/HR-/NST (55.7% vs. 70.5%, p<0.001). The chemotherapy frequency differed between the groups, with more chemotherapy applied in the HER2+/HR-/NST group (75.5%) compared with HER2-enriched APO tumors (67.1%). The two cohorts did not differ regarding the tumor stage, lymph node, and distant metastases' patterns. The cause of death was also significantly different between the groups, as only 4.2% of patients in the HER2+/HR-/APO group died of breast cancer, while 10.4% died of breast cancer in the HER2+/HR-/NST group (p=0.008). Consequently, the apocrine morphology was associated with a better BCSS in univariate analysis (p=0.030) (Figure 4 ). However, multivariate analysis did not reveal a significant difference in OS and BCSS between the HER2+/HR-/APO and NST groups. Discussion Breast carcinoma with apocrine differentiation is a rare (frequency ~1%) subtype of breast carcinoma whose diagnosis and clinical data, including outcome, remain challenging and controversial [ 14 , 19 ]. Based on the SEER data (2010-2016), the current study represents the largest HER2-positive APO cohort reported to date. Our findings indicate that HER2-positive APO carcinomas do substantially better compared with HER2-positive NST carcinomas. This is mainly reflected in BCSS and was independent of ER and PR status. Our results are in line with a recently published SEER cohort of triple-negative APO carcinomas, which also revealed that these cancers had a better prognosis than TNBC NST [ 23 ]. Several other independent studies confirmed a more favorable outcome for triple-negative APO patients [ 1 , 17 ]. In contrast, the studies of Dellapasqua et al. [ 4 ] and Bonnefoi et al. [ 2 ] reported a poor outcome of molecular apocrine tumors/pure apocrine carcinomas (as defined by gene expression analysis and/or immunohistochemistry) from the cohorts of the European Institute of Oncology and the EORTC 10994/BIG 1-00 phase III study, respectively. Saridakis et al. (2021) explored the status of apocrine carcinoma in the SEER database, reporting a more aggressive clinical course of APO than non-APO but without significant differences in BCSS [ 16 ]. Some other findings from our study are consistent with the previous data, including a rarity of APO carcinomas and a higher prevalence of APO tumors among elderly patients [ 14 , 21 , 24 ]. APO carcinomas typically lack ER and PR receptors [ 6 , 14 , 21 ], as confirmed in our study, given that 2/3 of the cases were negative for ER and PR, which was significantly lower than in the HER2+/NST cohort. In contrast, APO tumors consistently overexpress AR [ 6 ], but the AR status was not provided in the SEER database. This is understandable given the timeline of the collected data (2010-2016) and the fact that AR testing was only recently incorporated into a recommended diagnostic work-up of the breast's APO tumors [ 14 , 19 ]. Consequently, some of the tumors in the study, particularly ER/PR-positive, may not be true molecular apocrine carcinomas. Nevertheless, our subgroup analysis (HER2-enriched vs. Luminal B APO) revealed no significant differences between the two groups regarding clinicopathological parameters and survival (both OS and BCSS). We observed some clinically relevant differences between the APO and NST groups. Thus, HER2+/HR-/APO tumors had significantly lower histological grade than the NST carcinomas, which is in line with several previous studies and is probably due to the lower mitotic activity (and lower Ki-67 labeling) of apocrine cells [ 9 , 17 , 19 , 20 ]. Lower tumor grade may also contribute to the less aggressive behavior of HER2+/APO, as confirmed in a large cohort of IBS NST in which a high histological grade was a strong predictor of an adverse outcome [ 15 ]. In addition to this finding, the more advanced age of HER2+/APO patients probably contributed to substantially lower chemotherapy use in this group of patients. Nevertheless, the chemotherapy use did not affect the outcome, given a significantly better BCSS among HER2-enriched APO carcinomas than in the HER2-enriched NST cohort. The current study has several limitations that reflect the nature of the SEER database. Firstly, the follow-up period was too short (~31 months), and long-term outcomes could not be assessed. Secondly, AR was not routinely provided, which could affect the classification of a proportion of HER2+/APO cases, particularly ER/PR-positive. In addition, the details (types and duration) on chemotherapy, endocrine, and anti-HER2 therapies were not provided in the SEER database, so their effects (sensitivity, resistance) and the overall impact on the outcomes could not be analyzed. We conclude that our cohort represents the largest HER2+/APO study reported to date. It confirmed the rarity of the HER2+/APO carcinomas and revealed only marginal differences within the HER2+/APO carcinomas regardless of ER/PR status. Compared with HER2+/NST, HER2+/APO carcinomas tended to have a less aggressive phenotype and were associated with a more favorable clinical outcome (BCSS) despite a markedly lower/absent ER/PR expression. Further prospective studies should confirm the provided observations. Abbreviations APO Apocrine AR Androgen receptor BCSS Breast cancer-specific survival CI Confidence interval ER Estrogen receptor HR Hormonal receptor HR Hazard ratio IQR Interquartile range NST No special type OS Overall survival PR Progesterone receptor RLN Regional lymph nodes SEER Surveillance, Epidemiology, and End Results TNBC Triple-negative breast carcinoma Declarations Conflict of Interest The authors have no relevant financial or non-financial interests to disclose. Acknowledgment The preliminary results from the current study were presented at the 32nd Congress of the European Society of Pathology (ESP) and XXXIII International Congress of the International Academy of Pathology (IAP) in December 2020. Data availability statement The datasets from the study can be obtained from the corresponding author on reasonable request. CRediT Contributors Conceptualization, SV Data curation, FS, MAMA, ET Formal analysis, FS, MAMA, ET, YMA, ZG, SV Funding acquisition, SV Investigation, FS, MAMA, ET, YMA, ZG, SV Methodology, FS, MAMA, ET, SV Software, ET Supervision, ZG, SV Roles/Writing - original draft, FS, MAMA, ET, SV Writing - review & editing, ZG, SV Ethics statements Patient consent for publication Not applicable. Ethical approval is not required as the SEER database is a publicly available database with anonymized patients’ data. The corresponding author signed a SEER Research Data Agreement to use the data for research purposes. References Arciero CA, Diehl AH 3, Liu Y, Sun Q, Gillespie T, Li X, Subhedar P (2020) Triple-negative apocrine carcinoma: A rare pathologic subtype with a better prognosis than other triple-negative breast cancers. 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Eur J Surg Oncol 44:420–428. doi: 10.1016/j.ejso.2017.11.027 tables Variable Entire sample N (%) APO n (%) NST n (%) P-value - Pearson Chi Square (Fisher exact) Age <0.001 (0.002) 18-49 6722 (12.7) 23 (8.9) 6699 (12.7) 50-79 38050 (71.6) 172 (66.4) 37878 (71.7) ≥80 8347 (15.7) 64 (24.7) 8283 (15.7) Age mean (SD) <0.001 65.35 (13.79) 69.1 (14.27) 65.3 (13.78) Race 0.992 (0.994) Black 6795 (12.8) 33 (12.7) 6762 (12.8) White 39720 (74.8) 194 (74.9) 39526 (74.8) Other 6214 (11.7) 31 (12) 6183 (11.7) NA 390 (0.7) 1 (0.4) 389 (0.7) ER/PR Status (HR) <0.001 (<0.001) Negative 16353 (30.8) 167 (64.5) 16186 (30.6) Positive 36647 (69) 91 (35.1) 36556 (69.2) NA 119 (0.2) 1 (0.4) 118 (0.2) Grade 0.492 (0.512) I 2262 (4.3) 10 (3.9) 2252 (4.3) II 17870 (33.6) 96 (37.1) 17774 (33.6) III 30309 (57.1) 140 (54.1) 30169 (57.1) NA 2678 (5) 13 (5) 2665 (5) Stage 0.489 (0.450) I 19753 (37.2) 105 (40.5) 19648 (37.2) II 19905 (37.5) 86 (33.2) 19819 (37.5) III 7925 (14.9) 42 (16.2) 7883 (14.9) IV 4181 (7.9) 22 (8.5) 4159 (7.9) NA 1355 (2.6) 4 (1.5) 1351 (2.6) Tumor Size (cm) 0.731 (0.758) 5 5439 (10.2) 24 (9.3) 5415 (10.2) NA 3530 (6.6) 11 (4.2) 3519 (6.7) RLN status 0.292 (0.309) Negative 30564 (57.5) 158 (61) 30406 (57.5) Positive 21694 (40.8) 98 (37.8) 21596 (40.9) NA 861 (1.6) 3 (1.2) 858 (1.6) Distant Metastasis 0.379 (0.334) No 48890 (92) 235 (90.7) 48655 (92) Yes 3662 (6.9) 19 (7.3) 3643 (6.9) Unknown 567 (1.1) 5 (1.9) 562 (1.1) Cause of death 0.019 (0.018) Breast cancer 4109 (7.7) 10 (3.9) 4099 (7.8) Other 49010 (92.3) 249 (96.1) 48761 (92.2) Surgery Performed 0.538 (0.465) No 5490 (10.3) 25 (9.7) 5465 (10.3) Yes 46663 (87.8) 227 (87.6) 46436 (87.8) Unknown 966 (1.8) 7 (2.7) 959 (1.8) Chemotherapy 0.413 (0.403) No/Unknown 14591 (27.5) 77 (29.7) 14514 (27.5) Yes 38528 (72.5) 182 (70.3) 38346 (72.5) Radiation 0.0508 (0.0518) No/Unknown 29829 (56.2) 161 (62.2) 29668 (56.1) Yes 23290 (43.8) 98 (37.8) 23192 (43.9) Vital Status 0.097 (0.101) Alive 46845 (88.2) 237 (91.5) 46608 (88.2) Dead 6274 (11.8) 22 (8.5) 6252 (11.8) Follow up months median (IQR) 0.038 31 (39) 27 (35.5) 31 (39) NST, no special type; APO, apocrine; NA, not available; HR, hormone receptor (ER and PR); RLN, regional lymph node; IQR, interquartile range Only significant p-values are bolded. Table 1 . Clinicopathological characteristics of HER2+ breast cancer patients from the SEER database by histological subtype. Variable OS BCSS HR 95% CI p-value HR 95% CI p-value Histology Apocrine 1.000 NST 1.512 0.984 2.321 0.059 2.1913 1.1388 4.2168 0.018 Age 18-49 1.000 50-79 1.502 1.339 1.685 0.000 1.3956 1.2313 1.5817 0.001 ≥80 4.156 3.685 4.687 0.000 2.6913 2.3473 3.0858 0.001 Grade 1 1.000 2 1.117 0.958 1.301 1.000 1.5249 1.1901 1.954 0.001 3 1.336 1.150 1.553 0.000 1.9483 1.5255 2.4882 0.001 Stage I 1.000 II 2.062 1.900 2.238 0.000 3.0315 2.6642 3.4494 0.001 III 4.964 4.551 5.415 0.000 9.8249 8.6379 11.1751 0.001 IV 10.147 9.193 11.201 0.000 23.3762 20.3544 26.8465 0.001 Therapy Surgery (Yes) 0.385 0.357 0.415 0.000 0.3689 0.3375 0.4032 0.001 Chemotherapy (Yes) 0.414 0.390 0.439 0.000 0.4288 0.3976 0.4625 0.001 Radiation (Yes) 0.788 0.741 0.838 0.000 0.8452 0.7839 0.9113 0.001 NST, no special type; OS, overall survival; BCSS, breast cancer-specific survival; HR, hazard ratio; CI, confidence interval. Table 2 . Multivariate Cox Proportional Hazards model analysis of HER2+/APO vs. HER2+/NST group. Variable Entire sample (N and %) HER2+/ER/PR-/APO (N and %) HER2+/ER/PR+/APO (N and %) P-value - Pearson Chi-Square (Fisher exact) Age 0.893 (0.91) 18-49 23 (8.9) 14 (8.4) 8 (8.8) 50-79 172 (66.4) 110 (65.9) 62 (68.1) ≥80 64 (24.7) 43 (25.7) 21 (23.1) Age (mean), years (SD) 0.424 69.12 (14.27) 69.7 (14.33) 68.3 (14.06) Race 0.022 (0.018) Black 33 (12.7) 17 (10.2) 16 (17.6) White 194 (74.9) 123 (73.7) 70 (76.9) Other 31 (12) 26 (15.6) 5 (5.5) NA 1 (0.4) 1 (0.6) 0 (0) Estrogen Receptor <0.001 (<0.001) Negative 173 (66.8) 167 (100) 6 (6.6) Positive 85 (32.8) 0 (0) 85 (93.4) NA 1 (0.4) 0 (0) 0 (0) Progesterone Receptor <0.001 (<0.001) Negative 201 (77.6) 167 (100) 34 (37.4) Positive 56 (21.6) 0 (0) 56 (61.5) NA 2 (0.8) 0 (0) 1 (1.1) Grade 0.098 (0.099) 1 10 (3.9) 9 (5.4) 1 (1.1) 2 96 (37.1) 56 (33.5) 40 (44) 3 140 (54.1) 93 (55.7) 47 (51.6) NA 13 (5) 9 (5.4) 3 (3.3) Stage 0.889 (0.880) I 105 (40.5) 69 (41.3) 35 (38.5) II 86 (33.2) 54 (32.3) 32 (35.2) III 42 (16.2) 28 (16.8) 14 (15.4) IV 22 (8.5) 13 (7.8) 9 (9.9) NA 4 (1.5) 3 (1.8) 1 (1.1) Tumor size (cm) 0.917 (0.912) 5 24 (9.3) 15 (9) 9 (9.9) NA 11 (4.2) 6 (3.6) 5 (5.5) RLN status 0.333 (0.349) Negative 158 (61) 98 (58.7) 59 (64.8) Positive 98 (37.8) 67 (40.1) 31 (34.1) NA 3 (1.2) 2 (1.2) 1 (1.1) Distant Metastasis 0.536 (0.619) No 235 (90.7) 152 (91) 82 (90.1) Yes 19 (7.3) 11 (6.6) 8 (8.8) NA 5 (1.9) 4 (2.4) 1 (1.1) Cause Of Death 0.722 (1) Breast 10 (3.9) 7 (4.2) 3 (3.3) Other 249 (96.1) 160 (95.8) 88 (96.7) Surgery Performed 0.778 (0.843) No 32 (12.4) 20 (12) 12 (13.2) Yes 227 (87.6) 147 (88) 79 (86.8) Chemotherapy 0.097 (0.1161) No/Unknown 77 (29.7) 55 (32.9) 21 (23.1) Yes 182 (70.3) 112 (67.1) 70 (76.9) Radiation 0.5135 (0.5915) No/Unknown 161 (62.2) 106 (63.5) 54 (59.3) Yes 98 (37.8) 61 (36.5) 37 (40.7) Vital Status 0.4117 (0.49) Alive 237 (91.5) 151 (90.4) 85 (93.4) Dead 22 (8.5) 16 (9.6) 6 (6.6) Survival (Months, median and IQR) 0.199 27 (12.5, 48) 25(11,45) 28 (16.5, 50) Only significant p-values are bolded. Table 3 . Clinicopathological characteristics of the HER2+ apocrine cohort (HR+ vs. HR-). OS BCSS HR 95% CI p-value HR 95% CI p-value Histology Apocrine 1.000 1.000 NST 2.623 1.176 5.848 0.018 3.142 1.012 9.763 0.047 Age 18-49 1.000 1.000 50-79 1.551 1.338 1.798 0.000 1.411 1.201 1.659 0.000 ≥80 4.409 3.779 5.144 0.000 2.570 2.152 3.069 0.000 Grade 1 1.000 1.000 2 1.139 0.962 1.347 0.130 1.664 1.245 2.226 0.000 3 1.306 1.106 1.543 0.001 2.028 1.520 2.704 0.000 Stage I 1.000 1.000 II 2.025 1.831 2.239 0.000 3.037 2.571 3.587 0.000 III 4.633 4.150 5.172 0.000 9.792 8.277 11.585 0.000 IV 9.633 8.511 10.903 0.000 24.486 20.485 29.267 0.000 Therapy Surgery (Yes) 0.391 0.355 0.430 0.000 0.364 0.325 0.409 0.000 Chemotherapy (Yes) 0.419 0.388 0.452 0.000 0.425 0.386 0.469 0.000 Radiation (Yes) 0.729 0.674 0.787 0.000 0.768 0.695 0.847 0.000 OS, overall survival; BCSS, breast cancer-specific survival; NST, no special type; HR, hazard ratio; CI, confidence interval. Table 4 . Multivariate Cox proportional Hazard analysis of the HER2/HR+/APO vs. HER2/HR+/NST cohorts. Cite Share Download PDF Status: Under Review Version 2 posted Editorial decision: Minor Revisions Needed 12 Mar, 2022 Reviews received at journal 10 Feb, 2022 Editor assigned by journal 09 Feb, 2022 First submitted to journal 05 Feb, 2022 You are reading this latest preprint version Show more versions Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. Our growing team is made up of researchers and industry professionals working together to solve the most critical problems facing scientific publishing. Also discoverable on Platform About Our Team In Review Editorial Policies Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-1280152","acceptedTermsAndConditions":true,"allowDirectSubmit":false,"archivedVersions":[{"code":1,"date":"2022-01-24 22:07:34","editorialEvents":[{"type":"communityComments","content":0}],"status":"published","journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true}}],"articleType":"Research Article","associatedPublications":[],"authors":[{"id":84981893,"identity":"030782cb-44e4-4e5e-8642-7fb6211aa2dd","order_by":0,"name":"Faruk Skenderi","email":"","orcid":"","institution":"University of Sarajevo","correspondingAuthor":false,"submittingAuthor":false,"prefix":"","firstName":"Faruk","middleName":"","lastName":"Skenderi","suffix":""},{"id":84981894,"identity":"166e036f-4c86-48eb-bf27-f26fecf3241d","order_by":1,"name":"Mohamad Alhoda Mohamad Alahmad","email":"","orcid":"","institution":"University of Kansas Medical Center","correspondingAuthor":false,"submittingAuthor":false,"prefix":"","firstName":"Mohamad","middleName":"Alhoda Mohamad","lastName":"Alahmad","suffix":""},{"id":84981895,"identity":"4db59587-aa4e-4422-a1d7-7aaa441f85af","order_by":2,"name":"Emin Tahirovic","email":"","orcid":"","institution":"Internazionalni Univerzitet Sarajevo","correspondingAuthor":false,"submittingAuthor":false,"prefix":"","firstName":"Emin","middleName":"","lastName":"Tahirovic","suffix":""},{"id":84981896,"identity":"1d251a3a-5efb-4132-97f8-778e279e7555","order_by":3,"name":"Yaman M. Alahmad","email":"","orcid":"","institution":"Qatar University College of Medicine","correspondingAuthor":false,"submittingAuthor":false,"prefix":"","firstName":"Yaman","middleName":"M.","lastName":"Alahmad","suffix":""},{"id":84981897,"identity":"cba11840-6053-4112-bb35-e62318156820","order_by":4,"name":"Zoran Gatalica","email":"","orcid":"","institution":"The University of Oklahoma Health Sciences Center","correspondingAuthor":false,"submittingAuthor":false,"prefix":"","firstName":"Zoran","middleName":"","lastName":"Gatalica","suffix":""},{"id":84981898,"identity":"c999243c-330f-453c-839a-d3fa5504df9f","order_by":5,"name":"Semir Vranic","email":"data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAZAAAAAyAQMAAABI0h/eAAAABlBMVEX///8AAABVwtN+AAAACXBIWXMAAA7EAAAOxAGVKw4bAAAA5klEQVRIiWNgGAWjYJCCAxCKsYHhA5BiYydFC+MMkBZmUqxj5gGTBFTJt3cnHq5gOJzPP7u58bPNr23yfMwMjB8+5uDWYnDm7IaDZxgOW864c7BZOrfvtmEbMwOz5MxteLRI5G442MCQZsBwI7GNObfnNiNQCxszLx4t8vPfQrTIg7RY9ty2J6iF4QYvSIuNgQFIC8OP24kEtRicATnMwMbA8EZis2Rvw+3kNmbGZrx+kW8/u/ljQ4WEgdyN9Icffvy5bTu/vfngh4/4HAaxC0oztoHJBkLqkcEfUhSPglEwCkbBSAEA38hRvPjDEUcAAAAASUVORK5CYII=","orcid":"https://orcid.org/0000-0001-9743-7265","institution":"Qatar University College of Medicine","correspondingAuthor":true,"submittingAuthor":false,"prefix":"","firstName":"Semir","middleName":"","lastName":"Vranic","suffix":""}],"badges":[],"createdAt":"2022-01-20 14:11:22","currentVersionCode":2,"declarations":{"humanSubjects":false,"vertebrateSubjects":false,"conflictsOfInterestStatement":true,"humanSubjectEthicalGuidelines":false,"humanSubjectConsent":false,"humanSubjectClinicalTrial":false,"humanSubjectCaseReport":false,"vertebrateSubjectEthicalGuidelines":false,"coiExplicitlySet":false},"doi":"10.21203/rs.3.rs-1280152/v2","doiUrl":"https://doi.org/10.21203/rs.3.rs-1280152/v2","draftVersion":[],"editorialEvents":[],"editorialNote":"","failedWorkflow":false,"files":[{"id":18436848,"identity":"ab547559-ea87-462d-a682-057789e6bc63","added_by":"auto","created_at":"2022-02-21 14:57:44","extension":"jpg","order_by":1,"title":"Figure 1","display":"","copyAsset":false,"role":"figure","size":272537,"visible":true,"origin":"","legend":"\u003cp\u003eHER2+/APO carcinomas had seemingly better OS than HER2+/NST patients (Figure 1A); however, the difference was not statistically significant (p=0.264). Nevertheless, this effect was better seen in BCSS and almost reached a statistical significance (p=0.0508) (Figure 1B).\u003c/p\u003e","description":"","filename":"Figure1AB.jpg","url":"https://assets-eu.researchsquare.com/files/rs-1280152/v2/bfbe3788b4e300902b8efa8d.jpg"},{"id":18437620,"identity":"04c969a8-27ae-4f60-9ad3-9eb9e504f227","added_by":"auto","created_at":"2022-02-21 15:00:44","extension":"jpg","order_by":2,"title":"Figure 2","display":"","copyAsset":false,"role":"figure","size":164103,"visible":true,"origin":"","legend":"\u003cp\u003eOverall and breast cancer-specific survival Hazard ratios. Multivariate Cox Proportion Hazards model analysis of HER2+/APO vs. HER2+/NST group. Apocrine morphology in HER2+ breast cancer confers a lower hazard ratio than NST morphology (p=0.018).\u003c/p\u003e","description":"","filename":"Figure2.jpg","url":"https://assets-eu.researchsquare.com/files/rs-1280152/v2/5dbc31497d47887b9d6f3e9a.jpg"},{"id":18436849,"identity":"55976942-de06-4722-977c-565e058d21e8","added_by":"auto","created_at":"2022-02-21 14:57:44","extension":"jpg","order_by":3,"title":"Figure 3","display":"","copyAsset":false,"role":"figure","size":246606,"visible":true,"origin":"","legend":"\u003cp\u003eEstrogen and progesterone receptor (HR) status had no impact on survival as there was no difference in OS and BCSS between the two apocrine subgroups (p=0.304 and 0.615, respectively).\u003c/p\u003e","description":"","filename":"Figure3.jpg","url":"https://assets-eu.researchsquare.com/files/rs-1280152/v2/ab0616ba3ff471d69ccb5812.jpg"},{"id":18436851,"identity":"3d45ec1e-c979-43d8-a68e-abcc08df41f7","added_by":"auto","created_at":"2022-02-21 14:57:44","extension":"jpg","order_by":4,"title":"Figure 4","display":"","copyAsset":false,"role":"figure","size":250219,"visible":true,"origin":"","legend":"\u003cp\u003eApocrine morphology in HER2-enriched subgroups was associated with a better outcome in BCSS (p=0.03), while the difference was not seen in the OS analysis (p=0.22).\u003c/p\u003e","description":"","filename":"Figure4.jpg","url":"https://assets-eu.researchsquare.com/files/rs-1280152/v2/2701a6b86f2af3807e0dfd34.jpg"},{"id":18437634,"identity":"cc5da634-f7d0-448e-8f27-2488cf9f0d0e","added_by":"auto","created_at":"2022-02-21 15:00:48","extension":"pdf","order_by":0,"title":"","display":"","copyAsset":false,"role":"manuscript-pdf","size":752950,"visible":true,"origin":"","legend":"","description":"","filename":"manuscript.pdf","url":"https://assets-eu.researchsquare.com/files/rs-1280152/v2/ea5ad2ff-2ab4-47c3-9754-4a7b29cbde12.pdf"}],"financialInterests":"","formattedTitle":"HER2-positive Apocrine Carcinoma of the Breast: A population-based Analysis of Treatment and Outcome","fulltext":[{"header":"Introduction","content":"\u003cp\u003eBreast carcinoma with apocrine differentiation or apocrine carcinoma (APO) is a rare subtype of invasive breast cancer (~1%) that has a characteristic apocrine morphology along with the androgen receptor (AR) expression and the lack of estrogen receptor (ER) activity [\u003cspan citationid=\"CR3\" class=\"CitationRef\"\u003e3\u003c/span\u003e, \u003cspan citationid=\"CR14\" class=\"CitationRef\"\u003e14\u003c/span\u003e, \u003cspan citationid=\"CR21\" class=\"CitationRef\"\u003e21\u003c/span\u003e]. Based on the proposed classification, all APO are either triple-negative (50-70%) or HER2-positive (30-50%) [\u003cspan citationid=\"CR3\" class=\"CitationRef\"\u003e3\u003c/span\u003e, \u003cspan citationid=\"CR14\" class=\"CitationRef\"\u003e14\u003c/span\u003e, \u003cspan citationid=\"CR18\" class=\"CitationRef\"\u003e18\u003c/span\u003e, \u003cspan additionalcitationids=\"CR21\" citationid=\"CR20\" class=\"CitationRef\"\u003e20\u003c/span\u003e\u0026ndash;\u003cspan citationid=\"CR22\" class=\"CitationRef\"\u003e22\u003c/span\u003e].\u003c/p\u003e \u003cp\u003eThe available clinical data on APO are contradictory due to the rarity of the disease and the use of different diagnostic criteria for APO [\u003cspan citationid=\"CR14\" class=\"CitationRef\"\u003e14\u003c/span\u003e, \u003cspan citationid=\"CR19\" class=\"CitationRef\"\u003e19\u003c/span\u003e, \u003cspan citationid=\"CR21\" class=\"CitationRef\"\u003e21\u003c/span\u003e]. Several recent studies have reported a worse clinical outcome in patients with APO than invasive breast carcinoma no special type (IBC NST) [\u003cspan citationid=\"CR4\" class=\"CitationRef\"\u003e4\u003c/span\u003e, \u003cspan citationid=\"CR24\" class=\"CitationRef\"\u003e24\u003c/span\u003e]. However, in an analysis of the Surveillance, Epidemiology, and End Results (SEER) population-based data, the clinical outcome for the APO patients was significantly better than NST patients following the adjustment for demographic and clinicopathological characteristics [\u003cspan citationid=\"CR24\" class=\"CitationRef\"\u003e24\u003c/span\u003e]. Some studies also revealed more favorable overall survival (OS) and breast cancer-specific survival (BCSS) for patients with AR-positive triple-negative APO compared with other triple-negative breast carcinomas (TNBC) [\u003cspan additionalcitationids=\"CR11\" citationid=\"CR10\" class=\"CitationRef\"\u003e10\u003c/span\u003e\u0026ndash;\u003cspan citationid=\"CR12\" class=\"CitationRef\"\u003e12\u003c/span\u003e, \u003cspan citationid=\"CR25\" class=\"CitationRef\"\u003e25\u003c/span\u003e]. In contrast, other studies found no significant differences [\u003cspan citationid=\"CR5\" class=\"CitationRef\"\u003e5\u003c/span\u003e, \u003cspan citationid=\"CR13\" class=\"CitationRef\"\u003e13\u003c/span\u003e]. Wu et al. recently reported better clinical outcomes of triple-negative APO patients than TNBC NST [\u003cspan citationid=\"CR23\" class=\"CitationRef\"\u003e23\u003c/span\u003e]. The authors also found chemotherapy associated with a more favorable outcome among the triple-negative APO patients [\u003cspan citationid=\"CR23\" class=\"CitationRef\"\u003e23\u003c/span\u003e].\u003c/p\u003e \u003cp\u003eDespite the common HER2 expression, most of the available clinical studies have been focused on the triple-negative APO, while the clinical and survival data on HER2+/APO are sparse [\u003cspan citationid=\"CR7\" class=\"CitationRef\"\u003e7\u003c/span\u003e, \u003cspan citationid=\"CR8\" class=\"CitationRef\"\u003e8\u003c/span\u003e]. The current study explored the association between APO subtypes and survival after adjusting for all other prominent clinical and demographic predictors of survival among SEER patients.\u003c/p\u003e"},{"header":"Materials And Methods","content":"\u003cdiv id=\"Sec3\" class=\"Section2\"\u003e \u003ch2\u003ePatients' selection and cohorts\u003c/h2\u003e \u003cp\u003eWe explored the National Cancer Institute\u0026rsquo;s Surveillance, Epidemiology, and End Results (SEER) database to select our study cohort. The SEER database includes data on patients' demographics, tumor characteristics [Histotype, tumor grade, TNM stage (AJCC), tumor size, lymph node status, and distant metastases], the first course of treatment, treatment options (surgery, chemotherapy, radiotherapy), and follow-up for vital status. It encompasses data from eighteen population-based cancer registries covering approximately 1/3 of the US population.\u003c/p\u003e \u003cp\u003eFor our study cohort, we selected patients diagnosed with histologically confirmed invasive HER2-positive apocrine carcinoma (APO) (HER2+/APO) between 2010 and 2016. In addition, we selected patients diagnosed with IBC NST with HER2 positivity (HER2+/NST) within the same period. The two groups (HER2+/APO and HER2+/NST) were further divided based on the SEER variable that codes ER and PR [=HR] and HER2 status to form groups based on the intrinsic molecular subtypes, i.e., Apocrine Luminal B (HER2+/HR+/APO) and Apocrine HER2-Enriched (HER2+/HR-/APO) for HER2+/APO and HER2+/HR+/NST and HER2+/HR-/NST for HER2+/NST part of the cohort. HR status did not include androgen receptor. The study excluded in situ carcinomas (both apocrine and NST) and other special types of invasive breast carcinoma with HER2 positivity. We used the SEER*stat version 8.3.2 to generate a case-listing file.\u003c/p\u003e \u003c/div\u003e \u003cdiv id=\"Sec4\" class=\"Section2\"\u003e \u003ch2\u003eStatistical analysis\u003c/h2\u003e \u003cp\u003ePatients\u0026rsquo; demographical and clinicopathological characteristics, including age, hormone receptor status, stage, tumor grade, therapies (surgery, chemotherapy, radiotherapy), regional and distant metastases, as well as metastatic sites, were summarized by absolute and relative frequencies. Age was categorized as 18-49, 50-79, and \u0026ge;80 years. The difference in the distribution of clinicopathological characteristics was tested using Pearson chi-square and/or Fisher's exact test, whichever was appropriate according to the expected cell counts. For continuous normally distributed variables, we give mean and standard deviation as measures of central tendency and variability; for those whose distribution is not normal, we give a median and inter-quartile range instead. We tested the equality of means/medians for normally / non-normally distributed variables using the T-test/Mann-Whitney U test.\u003c/p\u003e \u003cp\u003eBreast cancer-specific survival (BCSS) and overall survival (OS) were defined as a time in years between the cancer diagnosis and death from breast cancer, death due to any cause, respectively. Patients alive at the end of the follow-up were censored for both types of survival. We ran univariate Cox proportional hazards analysis to identify candidate prognostic factors for the multivariate analysis. For each of these, we produced Kaplan-Meier plots and performed log-rank tests after checking the appropriateness of proportional hazard assumption graphically using martingale and weighted Schoenfeld residuals. After identifying and deciding which prognostic factors will enter the multivariate analyses, we fitted a multivariate Cox regression model to estimate the effect of subtypes on survival while adjusting for other prognostic factors. In the multivariate analysis of BCSS and OS, aside from the HER2+/APO status, we included age (categorical), stage, tumor grade, surgery, and systemic therapies. To provide an additional check of the robustness of our findings w.r.t. modeling assumptions assumed for multivariate Cox regression, we applied propensity score caliper matching in the ratio of 3:1 in favor of the \u0026ldquo;control\u0026rdquo; group (HER2+/NST). The propensity score was estimated via a multivariate logistic regression model that included age (in years, continuous), tumor grade, stage, size (in cm), lymph node status, the presence of distant metastasis, chemotherapy and radiation therapy. We applied the same model for propensity score and the same matching strategy for APO vs. NST comparisons (overall, HR+ and HR-) and the analysis for the effect of HR status among the APO subtype. All analyses were performed based on available cases using R Statistical Software (Foundation for Statistical Computing, Vienna, Austria) version 3.5.1. All tests were 2-sided, with p\u0026lt;0.05 considered statistically significant.\u003c/p\u003e \u003c/div\u003e"},{"header":"Results","content":"\u003cp\u003e\u003cspan class=\"BoldItalic\" name=\"Emphasis\" type=\"BoldItalic\"\u003e\u003cem\u003e\u003cstrong\u003eHER2+/APO vs. HER2+/NST cohorts\u003c/strong\u003e\u003c/em\u003e\u003c/span\u003e\u003c/p\u003e\n\u003cp\u003eThe clinicopathological characteristics of the cohorts are summarized in Table \u003cspan class=\"InternalRef\"\u003e1\u003c/span\u003e.\u003c/p\u003e\n\u003cp\u003eAmong 446,806 breast malignancies diagnosed between 2010 and 2016, there were 259 with HER2+ APO subtype (HER2+/APO) (~0.06%). We also identified 52,860 HER2+ IBC NST (HER2+/NST) in the same period. The median follow-up for the pooled cohort was 31 months (14\u0026thinsp;=\u0026thinsp;1st quartile, 53\u0026thinsp;=\u0026thinsp;3rd quartile); the median follow up for HER2+/APO was 27 months (12.5 =1st quartile, 48=3rd quartile) and 31 months (14=1st quartile, 53=3rd quartile) for HER2+/NST cohort (p=0.038, Table \u003cspan class=\"InternalRef\"\u003e1\u003c/span\u003e).\u003c/p\u003e\n\u003cp\u003eThe average age of patients was 69.1 years in the HER2+/APO group and 65.3 years in the HER2+/NST group (p\u0026lt;0.001). HER2+/APO carcinomas were more prevalent in 80+ age group (24.7%, n=64) compared with HER2+/NST cohort (15.7%, n=8283) (p\u0026lt;0.001). HER2+/APO carcinomas had a significantly lower HR (ER and PR) positivity than the HER2+/NST group (p\u0026lt;0.001) (Table \u003cspan class=\"InternalRef\"\u003e1\u003c/span\u003e). AR status was not routinely reported in the SEER database.\u003c/p\u003e\n\u003cp\u003eThe two groups did not differ significantly regarding the race, tumor stage, regional lymph node status or the presence of distant metastases (in general and in specific sites). The treatment options (surgery and chemotherapy) were similar between HER2+/APO and HER2+/NST (p\u0026gt;0.05), while radiotherapy was more commonly used in the HER2+/APO group compared to HER2+/NST (p=0.05) (Table \u003cspan class=\"InternalRef\"\u003e1\u003c/span\u003e).\u003c/p\u003e\n\u003cp\u003eAlthough at 18 months and onwards, the OS estimate in the HER2+/APO group was consistently higher, with unadjusted HR 1.26 (0.83, 1.92) from the univariate Cox proportional hazards model; however, this difference was not statistically significant (p=0.264) (Figure \u003cspan class=\"InternalRef\"\u003e1\u003c/span\u003eA). Nevertheless, the positive effect of apocrine morphology was more evident in BCSS analysis with unadjusted HR 1.83 (0.99, 3.42), hence 83% higher hazard for BCSS death in the HER2+/NST group. (Figure \u003cspan class=\"InternalRef\"\u003e1\u003c/span\u003eB).\u003c/p\u003e\n\u003cp\u003eBreast cancer as a cause of death was also more prevalent in HER2+/NST compared to the HER2+/APO group (7.8% vs. 3.9%, p=0.019). This difference was 1.5 times higher between ER-negative subgroups (4.2% in HER2+/HR-/APO vs. 10.4% in HER2+/HR-/NST, p=0.008). It was reflected in the results of the univariate analysis of BCSS in those groups with unadjusted HR 2.22 (1.06, 4.67) and adjusted (multivariate analysis) HR 2.07 (0.93, 4.62).\u003c/p\u003e\n\u003cp\u003eIn a multivariate Cox proportional hazards model analysis, HER2+/APO carcinoma patients had better OS (HR=1.512, CI=0.9-2.32, p=0.059) and significantly better BCSS (HR=2.19, CI 1.13-4.21, p=0.018) compared with HER2+/NST (Table \u003cspan class=\"InternalRef\"\u003e2\u003c/span\u003e, Figure \u003cspan class=\"InternalRef\"\u003e2\u003c/span\u003e).\u003c/p\u003e\n\u003cp\u003e\u003cspan class=\"BoldItalic\" name=\"Emphasis\" type=\"BoldItalic\"\u003e\u003cem\u003e\u003cstrong\u003eHER2+/HR-/APO vs. HER2+/HR+/APO cohorts\u003c/strong\u003e\u003c/em\u003e\u003c/span\u003e\u003c/p\u003e\n\u003cp\u003eThe clinicopathological characteristics of the HER2+/APO cohort are summarized in Table \u003cspan class=\"InternalRef\"\u003e3\u003c/span\u003e.\u003c/p\u003e\n\u003cp\u003eAmong the APO tumors, 167 cases were HER2+/HR- (HER2-enriched) (65%), while 91 patients (35%) were HER2+/HR+ (Luminal B) APO carcinomas. HER2+/HR+/APO subtype was more prevalent in the Black race, while HER2+/HR- APO carcinomas were more frequent in other races (neither black nor white) (p=0.022) (Table \u003cspan class=\"InternalRef\"\u003e3\u003c/span\u003e). Notably, there was no significant difference between the two APO subgroups regarding the tumor grade, stage, lymph node status, distant metastases in general and specific organs, cause of death, and therapeutic modalities (p\u0026gt;0.05, for all variables) (Table \u003cspan class=\"InternalRef\"\u003e3\u003c/span\u003e).\u003c/p\u003e\n\u003cp\u003eThe survival curves for two groups defined by HR status (ER and PR) were not significantly different by the log-rank test (Figure \u003cspan class=\"InternalRef\"\u003e3\u003c/span\u003e), although their shape was detectable by the log-rank test statistic. This was the case for both OS [HR 0.6 (0.54, 1.57)] and BCSS [HR 0.7 (0.18, 2.74)] in favor of HR-positive status. The patients aged \u0026ge;80 years had worse OS in univariate analysis (p\u0026lt;0.001); however, this age-related difference in survival curves completely dissipated when it came to BCSS (p=0.423).\u003c/p\u003e\n\u003cp\u003e\u003cspan class=\"BoldItalic\" name=\"Emphasis\" type=\"BoldItalic\"\u003e\u003cem\u003e\u003cstrong\u003eHER2+/HR+/APO vs. HER2+/HR+/NST cohorts\u003c/strong\u003e\u003c/em\u003e\u003c/span\u003e\u003c/p\u003e\n\u003cp\u003eThere were 91 HER2+/HR+/APO (Luminal B) cases and 36556 HER2+/HR+/NST (Luminal B) carcinomas. The mean age in HER2+/HR+/APO was 68.3 years, which was significantly higher than in the HER2+/HR+/NST group (65.2 years, p=0.035).\u003c/p\u003e\n\u003cp\u003eExcept for PR, which was less frequent in the HER2+/HR+/APO cohort, the two groups did not differ in clinicopathological parameters, including the treatment modalities. Although in univariate analysis no significant differences were observed, multivariate Cox proportional hazards analysis revealed that the apocrine morphology in HR+/HER2+ carcinomas was associated with better OS (HR=2.62, CI=1.17-5.84, p=0.018) and BCSS (HR=3.14, CI=1.01-9.76, p=0.047) (Table 4).\u003c/p\u003e\n\u003cp\u003e\u003cspan class=\"BoldItalic\" name=\"Emphasis\" type=\"BoldItalic\"\u003e\u003cem\u003e\u003cstrong\u003eHER2+/HR- APO vs. HER2+/HR- NST cohorts\u003c/strong\u003e\u003c/em\u003e\u003c/span\u003e\u003c/p\u003e\n\u003cp\u003eThere were 167 cases of HER2+/HR-/APO and 16186 HER2+/HR-/NST carcinomas. At diagnosis, the average age was 69.7 in the HER2+/HR-/APO group vs. 65.6 years in the HER2+/HR-/NST group. HER2+/HR-/APO was more prevalent in older populations than the HER2+/HR-/NST (p=0.001).\u003c/p\u003e\n\u003cp\u003eHER2+/HR-/APO had a significantly lower histological grade than the HER2+/HR-/NST (55.7% vs. 70.5%, p\u0026lt;0.001). The chemotherapy frequency differed between the groups, with more chemotherapy applied in the HER2+/HR-/NST group (75.5%) compared with HER2-enriched APO tumors (67.1%). The two cohorts did not differ regarding the tumor stage, lymph node, and distant metastases\u0026apos; patterns.\u003c/p\u003e\n\u003cp\u003eThe cause of death was also significantly different between the groups, as only 4.2% of patients in the HER2+/HR-/APO group died of breast cancer, while 10.4% died of breast cancer in the HER2+/HR-/NST group (p=0.008). Consequently, the apocrine morphology was associated with a better BCSS in univariate analysis (p=0.030) (Figure \u003cspan class=\"InternalRef\"\u003e4\u003c/span\u003e). However, multivariate analysis did not reveal a significant difference in OS and BCSS between the HER2+/HR-/APO and NST groups.\u003c/p\u003e"},{"header":"Discussion","content":"\u003cp\u003eBreast carcinoma with apocrine differentiation is a rare (frequency ~1%) subtype of breast carcinoma whose diagnosis and clinical data, including outcome, remain challenging and controversial [\u003cspan citationid=\"CR14\" class=\"CitationRef\"\u003e14\u003c/span\u003e, \u003cspan citationid=\"CR19\" class=\"CitationRef\"\u003e19\u003c/span\u003e]. Based on the SEER data (2010-2016), the current study represents the largest HER2-positive APO cohort reported to date.\u003c/p\u003e \u003cp\u003eOur findings indicate that HER2-positive APO carcinomas do substantially better compared with HER2-positive NST carcinomas. This is mainly reflected in BCSS and was independent of ER and PR status. Our results are in line with a recently published SEER cohort of triple-negative APO carcinomas, which also revealed that these cancers had a better prognosis than TNBC NST [\u003cspan citationid=\"CR23\" class=\"CitationRef\"\u003e23\u003c/span\u003e]. Several other independent studies confirmed a more favorable outcome for triple-negative APO patients [\u003cspan citationid=\"CR1\" class=\"CitationRef\"\u003e1\u003c/span\u003e, \u003cspan citationid=\"CR17\" class=\"CitationRef\"\u003e17\u003c/span\u003e]. In contrast, the studies of Dellapasqua et al. [\u003cspan citationid=\"CR4\" class=\"CitationRef\"\u003e4\u003c/span\u003e] and Bonnefoi et al. [\u003cspan citationid=\"CR2\" class=\"CitationRef\"\u003e2\u003c/span\u003e] reported a poor outcome of molecular apocrine tumors/pure apocrine carcinomas (as defined by gene expression analysis and/or immunohistochemistry) from the cohorts of the European Institute of Oncology and the EORTC 10994/BIG 1-00 phase III study, respectively. Saridakis et al. (2021) explored the status of apocrine carcinoma in the SEER database, reporting a more aggressive clinical course of APO than non-APO but without significant differences in BCSS [\u003cspan citationid=\"CR16\" class=\"CitationRef\"\u003e16\u003c/span\u003e].\u003c/p\u003e \u003cp\u003eSome other findings from our study are consistent with the previous data, including a rarity of APO carcinomas and a higher prevalence of APO tumors among elderly patients [\u003cspan citationid=\"CR14\" class=\"CitationRef\"\u003e14\u003c/span\u003e, \u003cspan citationid=\"CR21\" class=\"CitationRef\"\u003e21\u003c/span\u003e, \u003cspan citationid=\"CR24\" class=\"CitationRef\"\u003e24\u003c/span\u003e]. APO carcinomas typically lack ER and PR receptors [\u003cspan citationid=\"CR6\" class=\"CitationRef\"\u003e6\u003c/span\u003e, \u003cspan citationid=\"CR14\" class=\"CitationRef\"\u003e14\u003c/span\u003e, \u003cspan citationid=\"CR21\" class=\"CitationRef\"\u003e21\u003c/span\u003e], as confirmed in our study, given that 2/3 of the cases were negative for ER and PR, which was significantly lower than in the HER2+/NST cohort. In contrast, APO tumors consistently overexpress AR [\u003cspan citationid=\"CR6\" class=\"CitationRef\"\u003e6\u003c/span\u003e], but the AR status was not provided in the SEER database. This is understandable given the timeline of the collected data (2010-2016) and the fact that AR testing was only recently incorporated into a recommended diagnostic work-up of the breast's APO tumors [\u003cspan citationid=\"CR14\" class=\"CitationRef\"\u003e14\u003c/span\u003e, \u003cspan citationid=\"CR19\" class=\"CitationRef\"\u003e19\u003c/span\u003e]. Consequently, some of the tumors in the study, particularly ER/PR-positive, may not be true molecular apocrine carcinomas. Nevertheless, our subgroup analysis (HER2-enriched vs. Luminal B APO) revealed no significant differences between the two groups regarding clinicopathological parameters and survival (both OS and BCSS).\u003c/p\u003e \u003cp\u003eWe observed some clinically relevant differences between the APO and NST groups. Thus, HER2+/HR-/APO tumors had significantly lower histological grade than the NST carcinomas, which is in line with several previous studies and is probably due to the lower mitotic activity (and lower Ki-67 labeling) of apocrine cells [\u003cspan citationid=\"CR9\" class=\"CitationRef\"\u003e9\u003c/span\u003e, \u003cspan citationid=\"CR17\" class=\"CitationRef\"\u003e17\u003c/span\u003e, \u003cspan citationid=\"CR19\" class=\"CitationRef\"\u003e19\u003c/span\u003e, \u003cspan citationid=\"CR20\" class=\"CitationRef\"\u003e20\u003c/span\u003e]. Lower tumor grade may also contribute to the less aggressive behavior of HER2+/APO, as confirmed in a large cohort of IBS NST in which a high histological grade was a strong predictor of an adverse outcome [\u003cspan citationid=\"CR15\" class=\"CitationRef\"\u003e15\u003c/span\u003e]. In addition to this finding, the more advanced age of HER2+/APO patients probably contributed to substantially lower chemotherapy use in this group of patients. Nevertheless, the chemotherapy use did not affect the outcome, given a significantly better BCSS among HER2-enriched APO carcinomas than in the HER2-enriched NST cohort.\u003c/p\u003e \u003cp\u003eThe current study has several limitations that reflect the nature of the SEER database. Firstly, the follow-up period was too short (~31 months), and long-term outcomes could not be assessed. Secondly, AR was not routinely provided, which could affect the classification of a proportion of HER2+/APO cases, particularly ER/PR-positive. In addition, the details (types and duration) on chemotherapy, endocrine, and anti-HER2 therapies were not provided in the SEER database, so their effects (sensitivity, resistance) and the overall impact on the outcomes could not be analyzed.\u003c/p\u003e \u003cp\u003eWe conclude that our cohort represents the largest HER2+/APO study reported to date. It confirmed the rarity of the HER2+/APO carcinomas and revealed only marginal differences within the HER2+/APO carcinomas regardless of ER/PR status. Compared with HER2+/NST, HER2+/APO carcinomas tended to have a less aggressive phenotype and were associated with a more favorable clinical outcome (BCSS) despite a markedly lower/absent ER/PR expression. Further prospective studies should confirm the provided observations.\u003c/p\u003e"},{"header":"Abbreviations","content":"\u003cdiv class=\"DefinitionList\"\u003e \u003cdiv class=\"DefinitionListEntry\"\u003e \u003cdiv class=\"Term\"\u003eAPO\u003c/div\u003e \u003cdiv class=\"Description\"\u003e \u003cp\u003eApocrine\u003c/p\u003e \u003c/div\u003e \u003c/div\u003e \u003cdiv class=\"DefinitionListEntry\"\u003e \u003cdiv class=\"Term\"\u003eAR\u003c/div\u003e \u003cdiv class=\"Description\"\u003e \u003cp\u003eAndrogen receptor\u003c/p\u003e \u003c/div\u003e \u003c/div\u003e \u003cdiv class=\"DefinitionListEntry\"\u003e \u003cdiv class=\"Term\"\u003eBCSS\u003c/div\u003e \u003cdiv class=\"Description\"\u003e \u003cp\u003eBreast cancer-specific survival\u003c/p\u003e \u003c/div\u003e \u003c/div\u003e \u003cdiv class=\"DefinitionListEntry\"\u003e \u003cdiv class=\"Term\"\u003eCI\u003c/div\u003e \u003cdiv class=\"Description\"\u003e \u003cp\u003eConfidence interval\u003c/p\u003e \u003c/div\u003e \u003c/div\u003e \u003cdiv class=\"DefinitionListEntry\"\u003e \u003cdiv class=\"Term\"\u003eER\u003c/div\u003e \u003cdiv class=\"Description\"\u003e \u003cp\u003eEstrogen receptor\u003c/p\u003e \u003c/div\u003e \u003c/div\u003e \u003cdiv class=\"DefinitionListEntry\"\u003e \u003cdiv class=\"Term\"\u003eHR\u003c/div\u003e \u003cdiv class=\"Description\"\u003e \u003cp\u003eHormonal receptor\u003c/p\u003e \u003c/div\u003e \u003c/div\u003e \u003cdiv class=\"DefinitionListEntry\"\u003e \u003cdiv class=\"Term\"\u003eHR\u003c/div\u003e \u003cdiv class=\"Description\"\u003e \u003cp\u003eHazard ratio\u003c/p\u003e \u003c/div\u003e \u003c/div\u003e \u003cdiv class=\"DefinitionListEntry\"\u003e \u003cdiv class=\"Term\"\u003eIQR\u003c/div\u003e \u003cdiv class=\"Description\"\u003e \u003cp\u003eInterquartile range\u003c/p\u003e \u003c/div\u003e \u003c/div\u003e \u003cdiv class=\"DefinitionListEntry\"\u003e \u003cdiv class=\"Term\"\u003eNST\u003c/div\u003e \u003cdiv class=\"Description\"\u003e \u003cp\u003eNo special type\u003c/p\u003e \u003c/div\u003e \u003c/div\u003e \u003cdiv class=\"DefinitionListEntry\"\u003e \u003cdiv class=\"Term\"\u003eOS\u003c/div\u003e \u003cdiv class=\"Description\"\u003e \u003cp\u003eOverall survival\u003c/p\u003e \u003c/div\u003e \u003c/div\u003e \u003cdiv class=\"DefinitionListEntry\"\u003e \u003cdiv class=\"Term\"\u003ePR\u003c/div\u003e \u003cdiv class=\"Description\"\u003e \u003cp\u003eProgesterone receptor\u003c/p\u003e \u003c/div\u003e \u003c/div\u003e \u003cdiv class=\"DefinitionListEntry\"\u003e \u003cdiv class=\"Term\"\u003eRLN\u003c/div\u003e \u003cdiv class=\"Description\"\u003e \u003cp\u003eRegional lymph nodes\u003c/p\u003e \u003c/div\u003e \u003c/div\u003e \u003cdiv class=\"DefinitionListEntry\"\u003e \u003cdiv class=\"Term\"\u003eSEER\u003c/div\u003e \u003cdiv class=\"Description\"\u003e \u003cp\u003eSurveillance, Epidemiology, and End Results\u003c/p\u003e \u003c/div\u003e \u003c/div\u003e \u003cdiv class=\"DefinitionListEntry\"\u003e \u003cdiv class=\"Term\"\u003eTNBC\u003c/div\u003e \u003cdiv class=\"Description\"\u003e \u003cp\u003eTriple-negative breast carcinoma\u003c/p\u003e \u003c/div\u003e \u003c/div\u003e \u003c/div\u003e"},{"header":"Declarations","content":"\u003cp\u003e\u003cstrong\u003eConflict of Interest\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eThe authors have no relevant financial or non-financial interests to disclose.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eAcknowledgment\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eThe preliminary results from the current study were presented at the 32nd Congress of the European Society of Pathology (ESP) and XXXIII International Congress of the International Academy of Pathology (IAP) in December 2020.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eData availability statement\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eThe datasets from the study can be obtained from the corresponding author on reasonable request.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eCRediT Contributors \u0026nbsp;\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eConceptualization, SV\u003c/p\u003e\n\u003cp\u003eData curation, FS, MAMA, ET\u003c/p\u003e\n\u003cp\u003eFormal analysis, FS, MAMA, ET, YMA, ZG, SV\u003c/p\u003e\n\u003cp\u003eFunding acquisition, SV\u0026nbsp;\u003c/p\u003e\n\u003cp\u003eInvestigation, FS, MAMA, ET, YMA, ZG, SV\u003c/p\u003e\n\u003cp\u003eMethodology, FS, MAMA, ET, SV\u0026nbsp;\u003c/p\u003e\n\u003cp\u003eSoftware, ET\u0026nbsp;\u003c/p\u003e\n\u003cp\u003eSupervision, ZG, SV\u003c/p\u003e\n\u003cp\u003eRoles/Writing - original draft, FS, MAMA, ET, SV\u0026nbsp;\u003c/p\u003e\n\u003cp\u003eWriting - review \u0026amp; editing, ZG, SV\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eEthics statements\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003ePatient consent for publication\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eNot applicable. Ethical approval is not required as the SEER database is a publicly available database with anonymized patients\u0026rsquo; data. The corresponding author signed a SEER Research Data Agreement to use the data for research purposes.\u0026nbsp;\u003c/p\u003e"},{"header":"References","content":"\u003col\u003e\u003cli\u003e\u003cspan\u003eArciero CA, Diehl AH 3, Liu Y, Sun Q, Gillespie T, Li X, Subhedar P (2020) Triple-negative apocrine carcinoma: A rare pathologic subtype with a better prognosis than other triple-negative breast cancers. 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Mod Pathol 23:644\u0026ndash;653. doi: \u003cspan class=\"ExternalRef\"\u003e\u003cspan class=\"RefSource\"\u003e10.1038/modpathol.2010.50\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/li\u003e \u003cli\u003e\u003cspan\u003eWu W, Wu M, Peng G, Shi D, Zhang J (2019) Prognosis in triple-negative apocrine carcinomas of the breast: A population-based study. Cancer Med 8:7523\u0026ndash;7531. doi: \u003cspan class=\"ExternalRef\"\u003e\u003cspan class=\"RefSource\"\u003e10.1002/cam4.2634\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/li\u003e \u003cli\u003e\u003cspan\u003eZhang N, Zhang H, Chen T, Yang Q (2017) Dose invasive apocrine adenocarcinoma has worse prognosis than invasive ductal carcinoma of breast: evidence from SEER database. Oncotarget 8:24579\u0026ndash;24592. doi: \u003cspan class=\"ExternalRef\"\u003e\u003cspan class=\"RefSource\"\u003e10.18632/oncotarget.15597\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/li\u003e \u003cli\u003e\u003cspan\u003eZhao S, Ma D, Xiao Y, Jiang YZ, Shao ZM (2018) Clinicopathologic features and prognoses of different histologic types of triple-negative breast cancer: A large population-based analysis. Eur J Surg Oncol 44:420\u0026ndash;428. doi: \u003cspan class=\"ExternalRef\"\u003e\u003cspan class=\"RefSource\"\u003e10.1016/j.ejso.2017.11.027\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/li\u003e\u003c/ol\u003e"},{"header":"tables","content":"\u003ctable style=\"border: none;width:446.6pt;margin-left:-.25pt;border-collapse:collapse;\"\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 134.7pt;border-top: 1pt solid rgb(142, 169, 219);border-bottom: 1pt solid rgb(142, 169, 219);border-left: 1pt solid rgb(142, 169, 219);border-image: initial;border-right: none;background: rgb(68, 114, 196);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;color:white;\"\u003eVariable\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 77.95pt;border-top: 1pt solid rgb(142, 169, 219);border-left: none;border-bottom: 1pt solid rgb(142, 169, 219);border-right: none;background: rgb(68, 114, 196);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;color:white;\"\u003eEntire sample\u0026nbsp;\u003cbr\u003e\u0026nbsp;N (%)\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: 1pt solid rgb(142, 169, 219);border-left: none;border-bottom: 1pt solid rgb(142, 169, 219);border-right: none;background: rgb(68, 114, 196);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp 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style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026nbsp; \u0026nbsp;\u0026nbsp;\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(142, 169, 219);border-right: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026lt;0.001 (0.002)\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 134.7pt;border-top: none;border-left: 1pt solid rgb(142, 169, 219);border-bottom: 1pt solid rgb(142, 169, 219);border-right: none;background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e18-49\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 77.95pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e6722 (12.7)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e23 (8.9)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e6699 (12.7)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(142, 169, 219);border-right: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 134.7pt;border-top: none;border-left: 1pt solid rgb(142, 169, 219);border-bottom: 1pt solid rgb(142, 169, 219);border-right: none;padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e50-79\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 77.95pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e38050 (71.6)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e172 (66.4)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e37878 (71.7)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(142, 169, 219);border-right: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 134.7pt;border-top: none;border-left: 1pt solid rgb(142, 169, 219);border-bottom: 1pt solid rgb(142, 169, 219);border-right: none;background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026ge;80\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 77.95pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e8347 (15.7)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e64 (24.7)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e8283 (15.7)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(142, 169, 219);border-right: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 134.7pt;border-top: none;border-left: 1pt solid rgb(142, 169, 219);border-bottom: 1pt solid rgb(142, 169, 219);border-right: none;padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 77.95pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(142, 169, 219);border-right: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 134.7pt;border-top: none;border-left: 1pt solid rgb(142, 169, 219);border-bottom: 1pt solid rgb(142, 169, 219);border-right: none;background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eAge mean (SD)\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 77.95pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(142, 169, 219);border-right: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026lt;0.001\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 134.7pt;border-top: none;border-left: 1pt solid rgb(142, 169, 219);border-bottom: 1pt solid rgb(142, 169, 219);border-right: none;padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 77.95pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e65.35 (13.79)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e69.1 (14.27)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e65.3 (13.78)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(142, 169, 219);border-right: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 134.7pt;border-top: none;border-left: 1pt solid rgb(142, 169, 219);border-bottom: 1pt solid rgb(142, 169, 219);border-right: none;background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 77.95pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(142, 169, 219);border-right: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 134.7pt;border-top: none;border-left: 1pt solid rgb(142, 169, 219);border-bottom: 1pt solid rgb(142, 169, 219);border-right: none;padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eRace\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 77.95pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026nbsp; \u0026nbsp;\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026nbsp; \u0026nbsp;\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026nbsp; \u0026nbsp;\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(142, 169, 219);border-right: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e0.992 (0.994)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 134.7pt;border-top: none;border-left: 1pt solid rgb(142, 169, 219);border-bottom: 1pt solid rgb(142, 169, 219);border-right: none;background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eBlack\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 77.95pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e6795 (12.8)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 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0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(142, 169, 219);border-right: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 134.7pt;border-top: none;border-left: 1pt solid rgb(142, 169, 219);border-bottom: 1pt solid rgb(142, 169, 219);border-right: none;background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eGrade\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 77.95pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026nbsp; \u0026nbsp;\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026nbsp; 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style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e0.492 (0.512)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 134.7pt;border-top: none;border-left: 1pt solid rgb(142, 169, 219);border-bottom: 1pt solid rgb(142, 169, 219);border-right: none;padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eI\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 77.95pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e2262 (4.3)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e10 (3.9)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e2252 (4.3)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(142, 169, 219);border-right: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 134.7pt;border-top: none;border-left: 1pt solid rgb(142, 169, 219);border-bottom: 1pt solid rgb(142, 169, 219);border-right: none;background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eII\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 77.95pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e17870 (33.6)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e96 (37.1)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e17774 (33.6)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(142, 169, 219);border-right: 1pt solid rgb(142, 169, 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style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e30309 (57.1)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e140 (54.1)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e30169 (57.1)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(142, 169, 219);border-right: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 134.7pt;border-top: none;border-left: 1pt solid rgb(142, 169, 219);border-bottom: 1pt solid rgb(142, 169, 219);border-right: none;background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eNA\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 77.95pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e2678 (5)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e13 (5)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e2665 (5)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(142, 169, 219);border-right: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 134.7pt;border-top: none;border-left: 1pt solid rgb(142, 169, 219);border-bottom: 1pt solid rgb(142, 169, 219);border-right: none;padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 77.95pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(142, 169, 219);border-right: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 134.7pt;border-top: none;border-left: 1pt solid rgb(142, 169, 219);border-bottom: 1pt solid rgb(142, 169, 219);border-right: none;background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eStage\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 77.95pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026nbsp; \u0026nbsp;\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026nbsp; 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style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e0.489 (0.450)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 134.7pt;border-top: none;border-left: 1pt solid rgb(142, 169, 219);border-bottom: 1pt solid rgb(142, 169, 219);border-right: none;padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eI\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 77.95pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e19753 (37.2)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e105 (40.5)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e19648 (37.2)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(142, 169, 219);border-right: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 134.7pt;border-top: none;border-left: 1pt solid rgb(142, 169, 219);border-bottom: 1pt solid rgb(142, 169, 219);border-right: none;background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eII\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 77.95pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e19905 (37.5)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e86 (33.2)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e19819 (37.5)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(142, 169, 219);border-right: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 134.7pt;border-top: none;border-left: 1pt solid rgb(142, 169, 219);border-bottom: 1pt solid rgb(142, 169, 219);border-right: none;padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eIII\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 77.95pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e7925 (14.9)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e42 (16.2)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e7883 (14.9)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(142, 169, 219);border-right: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 134.7pt;border-top: none;border-left: 1pt solid rgb(142, 169, 219);border-bottom: 1pt solid rgb(142, 169, 219);border-right: none;background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eIV\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 77.95pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e4181 (7.9)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e22 (8.5)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e4159 (7.9)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(142, 169, 219);border-right: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 134.7pt;border-top: none;border-left: 1pt solid rgb(142, 169, 219);border-bottom: 1pt solid rgb(142, 169, 219);border-right: none;padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eNA\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 77.95pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e1355 (2.6)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e4 (1.5)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e1351 (2.6)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(142, 169, 219);border-right: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 134.7pt;border-top: none;border-left: 1pt solid rgb(142, 169, 219);border-bottom: 1pt solid rgb(142, 169, 219);border-right: none;background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 77.95pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(142, 169, 219);border-right: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 134.7pt;border-top: none;border-left: 1pt solid rgb(142, 169, 219);border-bottom: 1pt solid rgb(142, 169, 219);border-right: none;padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eTumor Size (cm)\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 77.95pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026nbsp; \u0026nbsp;\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026nbsp; \u0026nbsp;\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026nbsp; \u0026nbsp;\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(142, 169, 219);border-right: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e0.731 (0.758)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 134.7pt;border-top: none;border-left: 1pt solid rgb(142, 169, 219);border-bottom: 1pt solid rgb(142, 169, 219);border-right: none;background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026lt; 2\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 77.95pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e21939 (41.3)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e108 (41.7)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e21831 (41.3)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(142, 169, 219);border-right: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 134.7pt;border-top: none;border-left: 1pt solid rgb(142, 169, 219);border-bottom: 1pt solid rgb(142, 169, 219);border-right: none;padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e2 - 5\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 77.95pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e22211 (41.8)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e116 (44.8)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e22095 (41.8)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(142, 169, 219);border-right: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 134.7pt;border-top: none;border-left: 1pt solid rgb(142, 169, 219);border-bottom: 1pt solid rgb(142, 169, 219);border-right: none;background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026gt; 5\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 77.95pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e5439 (10.2)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e24 (9.3)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e5415 (10.2)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(142, 169, 219);border-right: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 134.7pt;border-top: none;border-left: 1pt solid rgb(142, 169, 219);border-bottom: 1pt solid rgb(142, 169, 219);border-right: none;padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eNA\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 77.95pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e3530 (6.6)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e11 (4.2)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e3519 (6.7)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(142, 169, 219);border-right: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 134.7pt;border-top: none;border-left: 1pt solid rgb(142, 169, 219);border-bottom: 1pt solid rgb(142, 169, 219);border-right: none;background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 77.95pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(142, 169, 219);border-right: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 134.7pt;border-top: none;border-left: 1pt solid rgb(142, 169, 219);border-bottom: 1pt solid rgb(142, 169, 219);border-right: none;padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eRLN status\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 77.95pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026nbsp; \u0026nbsp;\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026nbsp; \u0026nbsp;\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026nbsp; \u0026nbsp;\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(142, 169, 219);border-right: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e0.292 (0.309)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 134.7pt;border-top: none;border-left: 1pt solid rgb(142, 169, 219);border-bottom: 1pt solid rgb(142, 169, 219);border-right: none;background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eNegative\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 77.95pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e30564 (57.5)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e158 (61)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e30406 (57.5)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(142, 169, 219);border-right: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 134.7pt;border-top: none;border-left: 1pt solid rgb(142, 169, 219);border-bottom: 1pt solid rgb(142, 169, 219);border-right: none;padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003ePositive\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 77.95pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e21694 (40.8)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e98 (37.8)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e21596 (40.9)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(142, 169, 219);border-right: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 134.7pt;border-top: none;border-left: 1pt solid rgb(142, 169, 219);border-bottom: 1pt solid rgb(142, 169, 219);border-right: none;background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eNA\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 77.95pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e861 (1.6)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e3 (1.2)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e858 (1.6)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(142, 169, 219);border-right: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 134.7pt;border-top: none;border-left: 1pt solid rgb(142, 169, 219);border-bottom: 1pt solid rgb(142, 169, 219);border-right: none;padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 77.95pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(142, 169, 219);border-right: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 134.7pt;border-top: none;border-left: 1pt solid rgb(142, 169, 219);border-bottom: 1pt solid rgb(142, 169, 219);border-right: none;background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eDistant Metastasis\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 77.95pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026nbsp; \u0026nbsp;\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026nbsp; \u0026nbsp;\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026nbsp; \u0026nbsp;\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(142, 169, 219);border-right: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e0.379 (0.334)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 134.7pt;border-top: none;border-left: 1pt solid rgb(142, 169, 219);border-bottom: 1pt solid rgb(142, 169, 219);border-right: none;padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eNo\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 77.95pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e48890 (92)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e235 (90.7)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e48655 (92)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(142, 169, 219);border-right: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 134.7pt;border-top: none;border-left: 1pt solid rgb(142, 169, 219);border-bottom: 1pt solid rgb(142, 169, 219);border-right: none;background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eYes\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 77.95pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e3662 (6.9)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e19 (7.3)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e3643 (6.9)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(142, 169, 219);border-right: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 134.7pt;border-top: none;border-left: 1pt solid rgb(142, 169, 219);border-bottom: 1pt solid rgb(142, 169, 219);border-right: none;padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eUnknown\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 77.95pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e567 (1.1)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e5 (1.9)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e562 (1.1)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(142, 169, 219);border-right: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 134.7pt;border-top: none;border-left: 1pt solid rgb(142, 169, 219);border-bottom: 1pt solid rgb(142, 169, 219);border-right: none;background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 77.95pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(142, 169, 219);border-right: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 134.7pt;border-top: none;border-left: 1pt solid rgb(142, 169, 219);border-bottom: 1pt solid rgb(142, 169, 219);border-right: none;padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eCause of death\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 77.95pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026nbsp; \u0026nbsp;\u0026nbsp;\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026nbsp; \u0026nbsp;\u0026nbsp;\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026nbsp; \u0026nbsp;\u0026nbsp;\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(142, 169, 219);border-right: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e0.019 (0.018)\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 134.7pt;border-top: none;border-left: 1pt solid rgb(142, 169, 219);border-bottom: 1pt solid rgb(142, 169, 219);border-right: none;background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eBreast cancer\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 77.95pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e4109 (7.7)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e10 (3.9)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e4099 (7.8)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(142, 169, 219);border-right: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 134.7pt;border-top: none;border-left: 1pt solid rgb(142, 169, 219);border-bottom: 1pt solid rgb(142, 169, 219);border-right: none;padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eOther\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 77.95pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e49010 (92.3)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e249 (96.1)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e48761 (92.2)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(142, 169, 219);border-right: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 134.7pt;border-top: none;border-left: 1pt solid rgb(142, 169, 219);border-bottom: 1pt solid rgb(142, 169, 219);border-right: none;background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 77.95pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(142, 169, 219);border-right: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 134.7pt;border-top: none;border-left: 1pt solid rgb(142, 169, 219);border-bottom: 1pt solid rgb(142, 169, 219);border-right: none;padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eSurgery Performed\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 77.95pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026nbsp; \u0026nbsp;\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026nbsp; \u0026nbsp;\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026nbsp; \u0026nbsp;\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(142, 169, 219);border-right: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e0.538 (0.465)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 134.7pt;border-top: none;border-left: 1pt solid rgb(142, 169, 219);border-bottom: 1pt solid rgb(142, 169, 219);border-right: none;background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eNo\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 77.95pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e5490 (10.3)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e25 (9.7)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e5465 (10.3)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(142, 169, 219);border-right: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 134.7pt;border-top: none;border-left: 1pt solid rgb(142, 169, 219);border-bottom: 1pt solid rgb(142, 169, 219);border-right: none;padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eYes\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 77.95pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e46663 (87.8)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e227 (87.6)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e46436 (87.8)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(142, 169, 219);border-right: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 134.7pt;border-top: none;border-left: 1pt solid rgb(142, 169, 219);border-bottom: 1pt solid rgb(142, 169, 219);border-right: none;background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eUnknown\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 77.95pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e966 (1.8)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e7 (2.7)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e959 (1.8)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(142, 169, 219);border-right: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 134.7pt;border-top: none;border-left: 1pt solid rgb(142, 169, 219);border-bottom: 1pt solid rgb(142, 169, 219);border-right: none;padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 77.95pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt 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style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e38528 (72.5)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e182 (70.3)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 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1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(142, 169, 219);border-right: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 134.7pt;border-top: none;border-left: 1pt solid rgb(142, 169, 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style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eNo/Unknown\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 77.95pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e29829 (56.2)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e161 (62.2)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e29668 (56.1)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(142, 169, 219);border-right: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: 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style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e23290 (43.8)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e98 (37.8)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e23192 (43.9)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(142, 169, 219);border-right: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 134.7pt;border-top: none;border-left: 1pt solid rgb(142, 169, 219);border-bottom: 1pt solid rgb(142, 169, 219);border-right: none;padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 77.95pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(142, 169, 219);border-right: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 134.7pt;border-top: none;border-left: 1pt solid rgb(142, 169, 219);border-bottom: 1pt solid rgb(142, 169, 219);border-right: none;background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eVital Status\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 77.95pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026nbsp; \u0026nbsp;\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026nbsp; \u0026nbsp;\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026nbsp; \u0026nbsp;\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(142, 169, 219);border-right: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e0.097 (0.101)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 134.7pt;border-top: none;border-left: 1pt solid rgb(142, 169, 219);border-bottom: 1pt solid rgb(142, 169, 219);border-right: none;padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eAlive\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 77.95pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e46845 (88.2)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e237 (91.5)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e46608 (88.2)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(142, 169, 219);border-right: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 134.7pt;border-top: none;border-left: 1pt solid rgb(142, 169, 219);border-bottom: 1pt solid rgb(142, 169, 219);border-right: none;background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eDead\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 77.95pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e6274 (11.8)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e22 (8.5)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e6252 (11.8)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(142, 169, 219);border-right: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 134.7pt;border-top: none;border-left: 1pt solid rgb(142, 169, 219);border-bottom: 1pt solid rgb(142, 169, 219);border-right: none;padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 77.95pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(142, 169, 219);border-right: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 134.7pt;border-top: none;border-left: 1pt solid rgb(142, 169, 219);border-bottom: 1pt solid rgb(142, 169, 219);border-right: none;background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eFollow up months median (IQR)\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 77.95pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(142, 169, 219);border-right: 1pt solid rgb(142, 169, 219);background: rgb(217, 225, 242);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e0.038\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 134.7pt;border-top: none;border-left: 1pt solid rgb(142, 169, 219);border-bottom: 1pt solid rgb(142, 169, 219);border-right: none;padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 77.95pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e31 (39)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e27 (35.5)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 70.9pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e31 (39)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(142, 169, 219);border-right: 1pt solid rgb(142, 169, 219);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd colspan=\"5\" style=\"width: 446.6pt;border-right: 1pt solid rgb(142, 169, 219);border-bottom: 1pt solid rgb(142, 169, 219);border-left: 1pt solid rgb(142, 169, 219);border-image: initial;border-top: none;padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:8.0pt;line-height:107%;'\u003e\u003cspan style=\"font-size:12px;line-height:107%;color:black;\"\u003eNST, no special type; APO, apocrine; NA, not available; HR, hormone receptor (ER and PR); RLN, regional lymph node; IQR, interquartile range\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003c/tbody\u003e\n\u003c/table\u003e\n\u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:8.0pt;line-height:normal;'\u003e\u003cspan style=\"font-size:13px;color:black;\"\u003eOnly significant p-values are bolded.\u003c/span\u003e\u003c/p\u003e\n\u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:8.0pt;line-height:normal;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:16px;\"\u003eTable 1\u003c/span\u003e\u003c/strong\u003e\u003cspan style=\"font-size:16px;\"\u003e. Clinicopathological characteristics of HER2+ breast cancer patients from the SEER database by histological subtype.\u003c/span\u003e\u003cspan style='font-size:16px;line-height:107%;font-family:\"Calibri\",sans-serif;'\u003e\u003cbr\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n\u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:8.0pt;line-height:107%;'\u003e\u003cspan style=\"font-size:16px;line-height:107%;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n\u003ctable style=\"border: none;width:467.35pt;border-collapse:collapse;\"\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 107.75pt;border: 1pt solid windowtext;padding: 0in 5.4pt;height: 13.8pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:13px;\"\u003eVariable\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"4\" style=\"width: 161.15pt;border-top: 1pt solid windowtext;border-right: 1pt solid windowtext;border-bottom: 1pt solid windowtext;border-image: initial;border-left: none;padding: 0in 5.4pt;height: 13.8pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:center;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:13px;color:black;\"\u003eOS\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 13.35pt;border-top: 1pt solid windowtext;border-right: 1pt solid windowtext;border-bottom: 1pt solid windowtext;border-image: initial;border-left: none;padding: 0in 5.4pt;height: 13.8pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd colspan=\"4\" style=\"width: 185.1pt;border-top: 1pt solid windowtext;border-right: 1pt solid windowtext;border-bottom: 1pt solid windowtext;border-image: initial;border-left: none;padding: 0in 5.4pt;height: 13.8pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:center;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:13px;color:black;\"\u003eBCSS\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 107.75pt;border-right: 1pt solid windowtext;border-bottom: 1pt solid windowtext;border-left: 1pt solid windowtext;border-image: initial;border-top: none;padding: 0in 5.4pt;height: 13.8pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 40.5pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 13.8pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:center;'\u003e\u003cspan style=\"font-size:13px;color:black;\"\u003eHR\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"2\" style=\"width: 76.5pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 13.8pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:center;'\u003e\u003cspan style=\"font-size:13px;color:black;\"\u003e95% CI\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 44.15pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 13.8pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:center;'\u003e\u003cspan style=\"font-size:13px;color:black;\"\u003ep-value\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 13.35pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 13.8pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 49.45pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 13.8pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:center;'\u003e\u003cspan style=\"font-size:13px;color:black;\"\u003eHR\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"2\" style=\"width: 93.15pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 13.8pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:center;'\u003e\u003cspan style=\"font-size:13px;color:black;\"\u003e95% CI\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42.5pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 13.8pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:center;'\u003e\u003cspan style=\"font-size:13px;color:black;\"\u003ep-value\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 107.75pt;border-right: 1pt solid windowtext;border-bottom: 1pt solid windowtext;border-left: 1pt solid windowtext;border-image: initial;border-top: none;background: rgb(237, 237, 237);padding: 0in 5.4pt;height: 14.1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:13px;color:black;\"\u003eHistology\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 40.5pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;background: rgb(237, 237, 237);padding: 0in 5.4pt;height: 14.1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:center;'\u003e\u003cspan style=\"font-size:13px;color:black;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 0.5in;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;background: rgb(237, 237, 237);padding: 0in 5.4pt;height: 14.1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:13px;color:black;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 40.5pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;background: rgb(237, 237, 237);padding: 0in 5.4pt;height: 14.1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:13px;color:black;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 44.15pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;background: rgb(237, 237, 237);padding: 0in 5.4pt;height: 14.1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:13px;color:black;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 13.35pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;background: rgb(237, 237, 237);padding: 0in 5.4pt;height: 14.1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:13px;color:black;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 49.45pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;background: rgb(237, 237, 237);padding: 0in 5.4pt;height: 14.1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:13px;color:black;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 49.4pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;background: rgb(237, 237, 237);padding: 0in 5.4pt;height: 14.1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:13px;color:black;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 43.75pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;background: rgb(237, 237, 237);padding: 0in 5.4pt;height: 14.1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:13px;color:black;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42.5pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;background: rgb(237, 237, 237);padding: 0in 5.4pt;height: 14.1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:13px;color:black;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 107.75pt;border-right: 1pt solid windowtext;border-bottom: 1pt solid windowtext;border-left: 1pt solid windowtext;border-image: initial;border-top: none;padding: 0in 5.4pt;height: 13.8pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:10.0pt;'\u003e\u003cspan style=\"font-size:13px;color:black;\"\u003eApocrine\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 40.5pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 13.8pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cspan style=\"font-size:13px;color:black;\"\u003e1.000\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 0.5in;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 13.8pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 40.5pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 13.8pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 44.15pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 13.8pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 13.35pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 13.8pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 49.45pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 13.8pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 49.4pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 13.8pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 43.75pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 13.8pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 42.5pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 13.8pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 107.75pt;border-right: 1pt solid windowtext;border-bottom: 1pt solid windowtext;border-left: 1pt solid windowtext;border-image: initial;border-top: none;padding: 0in 5.4pt;height: 14.1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:10.0pt;'\u003e\u003cspan style=\"font-size:13px;color:black;\"\u003eNST\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 40.5pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 14.1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cspan style=\"font-size:13px;color:black;\"\u003e1.512\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 0.5in;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 14.1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cspan style=\"font-size:13px;color:black;\"\u003e0.984\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 40.5pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 14.1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cspan style=\"font-size:13px;color:black;\"\u003e2.321\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 44.15pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 14.1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:13px;color:black;\"\u003e0.059\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 13.35pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 14.1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 49.45pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 14.1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cspan style=\"font-size:13px;color:black;\"\u003e2.1913\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 49.4pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 14.1pt;vertical-align: bottom;\"\u003e\n \u003cp 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style=\"font-size:13px;color:black;\"\u003e0.3689\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 49.4pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 14.1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cspan style=\"font-size:13px;color:black;\"\u003e0.3375\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 43.75pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 14.1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cspan style=\"font-size:13px;color:black;\"\u003e0.4032\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42.5pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 14.1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:13px;color:black;\"\u003e0.001\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width:107.75pt;border:solid windowtext 1.0pt;border-top:none;padding:0in 5.4pt 0in 5.4pt;height:14.1pt;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:10.0pt;'\u003e\u003cspan style=\"font-size:13px;color:black;\"\u003eChemotherapy (Yes)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 40.5pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 14.1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cspan style=\"font-size:13px;color:black;\"\u003e0.414\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 0.5in;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 14.1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cspan style=\"font-size:13px;color:black;\"\u003e0.390\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 40.5pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 14.1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cspan style=\"font-size:13px;color:black;\"\u003e0.439\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 44.15pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 14.1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:13px;color:black;\"\u003e0.000\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 13.35pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 14.1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 49.45pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 14.1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cspan style=\"font-size:13px;color:black;\"\u003e0.4288\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 49.4pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 14.1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cspan style=\"font-size:13px;color:black;\"\u003e0.3976\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 43.75pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 14.1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cspan style=\"font-size:13px;color:black;\"\u003e0.4625\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42.5pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 14.1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:13px;color:black;\"\u003e0.001\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width:107.75pt;border:solid windowtext 1.0pt;border-top:none;padding:0in 5.4pt 0in 5.4pt;height:14.1pt;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:10.0pt;'\u003e\u003cspan style=\"font-size:13px;color:black;\"\u003eRadiation (Yes)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 40.5pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 14.1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cspan style=\"font-size:13px;color:black;\"\u003e0.788\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 0.5in;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 14.1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cspan style=\"font-size:13px;color:black;\"\u003e0.741\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 40.5pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 14.1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cspan style=\"font-size:13px;color:black;\"\u003e0.838\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 44.15pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 14.1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:13px;color:black;\"\u003e0.000\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 13.35pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 14.1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 49.45pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 14.1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cspan style=\"font-size:13px;color:black;\"\u003e0.8452\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 49.4pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 14.1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cspan style=\"font-size:13px;color:black;\"\u003e0.7839\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 43.75pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 14.1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cspan style=\"font-size:13px;color:black;\"\u003e0.9113\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42.5pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 14.1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:13px;color:black;\"\u003e0.001\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003c/tbody\u003e\n\u003c/table\u003e\n\u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:8.0pt;line-height:normal;'\u003e\u003cspan style=\"font-size: 13px; color: rgb(0, 0, 0);\"\u003eNST, no special type; OS, overall survival; BCSS, breast cancer-specific survival; HR, hazard ratio; CI, confidence interval.\u003c/span\u003e\u003c/p\u003e\n\u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:8.0pt;line-height:normal;'\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cstrong\u003e\u003cspan style=\"font-size:16px;\"\u003eTable 2\u003c/span\u003e\u003c/strong\u003e\u003c/span\u003e\u003cspan style=\"font-size: 16px; color: rgb(0, 0, 0);\"\u003e. Multivariate Cox Proportional Hazards model analysis of HER2+/APO vs. HER2+/NST group.\u003c/span\u003e\u003c/p\u003e\n\u003cp\u003e\u003cbr\u003e\u003c/p\u003e\n\u003ctable style=\"border: none;width:459.0pt;margin-left:-.25pt;border-collapse:collapse;\"\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-left: 1pt solid rgb(149, 179, 215);border-image: initial;border-right: none;background: rgb(79, 129, 189);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;color:white;\"\u003eVariable\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: 1pt solid rgb(149, 179, 215);border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;background: rgb(79, 129, 189);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;color:white;\"\u003eEntire sample\u0026nbsp;\u003cbr\u003e\u0026nbsp;(N and %)\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: 1pt solid rgb(149, 179, 215);border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;background: rgb(79, 129, 189);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;color:white;\"\u003eHER2+/ER/PR-/APO\u003cbr\u003e\u0026nbsp;(N and %)\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: 1pt solid rgb(149, 179, 215);border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;background: rgb(79, 129, 189);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;color:white;\"\u003eHER2+/ER/PR+/APO\u003cbr\u003e\u0026nbsp;(N and %)\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 96pt;border-top: 1pt solid rgb(149, 179, 215);border-right: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-image: initial;border-left: none;background: rgb(79, 129, 189);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;color:white;\"\u003eP-value - Pearson Chi-Square (Fisher exact)\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 96pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eAge\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026nbsp; \u0026nbsp;\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026nbsp; \u0026nbsp;\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026nbsp; \u0026nbsp;\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 96pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e0.893 (0.91)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e18-49\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e23 (8.9)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e14 (8.4)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e8 (8.8)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 96pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e50-79\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e172 (66.4)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e110 (65.9)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e62 (68.1)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 96pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026ge;80\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e64 (24.7)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e43 (25.7)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e21 (23.1)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 96pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 96pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eAge (mean), years (SD)\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 96pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e0.424\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e69.12 (14.27)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e69.7 (14.33)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e68.3 (14.06)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 96pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 96pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eRace\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026nbsp; \u0026nbsp;\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026nbsp; \u0026nbsp;\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026nbsp; \u0026nbsp;\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 96pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e0.022 (0.018)\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eBlack\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e33 (12.7)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e17 (10.2)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e16 (17.6)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 96pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eWhite\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e194 (74.9)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e123 (73.7)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e70 (76.9)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 96pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eOther\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e31 (12)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e26 (15.6)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e5 (5.5)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 96pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eNA\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e1 (0.4)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e1 (0.6)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e0 (0)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 96pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 96pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eEstrogen Receptor\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026nbsp; \u0026nbsp;\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026nbsp; \u0026nbsp;\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026nbsp; \u0026nbsp;\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 96pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026lt;0.001 (\u0026lt;0.001)\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eNegative\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e173 (66.8)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e167 (100)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e6 (6.6)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 96pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003ePositive\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e85 (32.8)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e0 (0)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp 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1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 96pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eProgesterone Receptor\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026nbsp; \u0026nbsp;\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026nbsp; 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style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026lt;0.001 (\u0026lt;0.001)\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eNegative\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e201 (77.6)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e167 (100)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e34 (37.4)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 96pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003ePositive\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e56 (21.6)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 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rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eNA\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e2 (0.8)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e0 (0)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e1 (1.1)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 96pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 96pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eGrade\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026nbsp; \u0026nbsp;\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026nbsp; \u0026nbsp;\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026nbsp; \u0026nbsp;\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n 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style=\"font-size:12px;color:black;\"\u003e1\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e10 (3.9)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e9 (5.4)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e1 (1.1)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 96pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e2\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e96 (37.1)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e56 (33.5)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e40 (44)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 96pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e3\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e140 (54.1)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e93 (55.7)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e47 (51.6)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 96pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eNA\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e13 (5)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n 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179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 96pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eStage\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026nbsp; \u0026nbsp;\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026nbsp; \u0026nbsp;\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n 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style=\"font-size:12px;color:black;\"\u003e105 (40.5)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e69 (41.3)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e35 (38.5)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 96pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eII\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e86 (33.2)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e54 (32.3)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e32 (35.2)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 96pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eIII\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e42 (16.2)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e28 (16.8)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e14 (15.4)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 96pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eIV\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e22 (8.5)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e13 (7.8)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e9 (9.9)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 96pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eNA\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e4 (1.5)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e3 (1.8)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e1 (1.1)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 96pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 96pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eTumor size (cm)\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026nbsp; \u0026nbsp;\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026nbsp; \u0026nbsp;\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026nbsp; \u0026nbsp;\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 96pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e0.917 (0.912)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026lt; 2\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e108 (41.7)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e69 (41.3)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e38 (41.8)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 96pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e2 - 5\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e116 (44.8)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e77 (46.1)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e39 (42.9)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 96pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026gt; 5\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e24 (9.3)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e15 (9)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e9 (9.9)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 96pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eNA\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e11 (4.2)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e6 (3.6)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e5 (5.5)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 96pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 96pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eRLN status\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026nbsp; \u0026nbsp;\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026nbsp; \u0026nbsp;\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026nbsp; \u0026nbsp;\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 96pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e0.333 (0.349)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eNegative\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e158 (61)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e98 (58.7)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e59 (64.8)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 96pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003ePositive\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e98 (37.8)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e67 (40.1)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e31 (34.1)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 96pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eNA\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e3 (1.2)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e2 (1.2)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e1 (1.1)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 96pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 96pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eDistant Metastasis\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026nbsp; \u0026nbsp;\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026nbsp; \u0026nbsp;\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026nbsp; \u0026nbsp;\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 96pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e0.536 (0.619)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eNo\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e235 (90.7)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e152 (91)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e82 (90.1)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 96pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eYes\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e19 (7.3)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e11 (6.6)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e8 (8.8)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 96pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eNA\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e5 (1.9)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e4 (2.4)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e1 (1.1)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 96pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 96pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eCause Of Death\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026nbsp; \u0026nbsp;\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026nbsp; \u0026nbsp;\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026nbsp; \u0026nbsp;\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 96pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e0.722 (1)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eBreast\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e10 (3.9)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e7 (4.2)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e3 (3.3)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 96pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eOther\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e249 (96.1)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e160 (95.8)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e88 (96.7)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 96pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 96pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eSurgery Performed\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026nbsp; \u0026nbsp;\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026nbsp; \u0026nbsp;\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026nbsp; \u0026nbsp;\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 96pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e0.778 (0.843)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eNo\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e32 (12.4)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e20 (12)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e12 (13.2)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 96pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eYes\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e227 (87.6)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e147 (88)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e79 (86.8)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 96pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 96pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eChemotherapy\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026nbsp; \u0026nbsp;\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026nbsp; \u0026nbsp;\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026nbsp; \u0026nbsp;\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 96pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e0.097 (0.1161)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eNo/Unknown\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e77 (29.7)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e55 (32.9)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e21 (23.1)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 96pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eYes\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e182 (70.3)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e112 (67.1)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e70 (76.9)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 96pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 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rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eRadiation\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026nbsp; \u0026nbsp;\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: 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style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:9.0pt;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eNo/Unknown\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e161 (62.2)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp 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rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eVital Status\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e\u0026nbsp; \u0026nbsp;\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: 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style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e151 (90.4)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e85 (93.4)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 96pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n 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style=\"font-size:12px;color:black;\"\u003e22 (8.5)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e16 (9.6)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e6 (6.6)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 96pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 96pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003eSurvival (Months, median and IQR)\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 96pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: 1pt solid rgb(149, 179, 215);background: rgb(220, 230, 241);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e0.199\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 112pt;border-top: none;border-left: 1pt solid rgb(149, 179, 215);border-bottom: 1pt solid rgb(149, 179, 215);border-right: none;padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 75pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e27 (12.5, 48)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e25(11,45)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 89pt;border-top: none;border-right: none;border-left: none;border-image: initial;border-bottom: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:12px;color:black;\"\u003e28 \u0026nbsp;(16.5, 50)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 96pt;border-top: none;border-left: none;border-bottom: 1pt solid rgb(149, 179, 215);border-right: 1pt solid rgb(149, 179, 215);padding: 0in 5.4pt;height: 1pt;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003c/tbody\u003e\n\u003c/table\u003e\n\u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:8.0pt;line-height:normal;'\u003e\u003cspan style=\"font-size:13px;\"\u003eOnly significant p-values are bolded.\u003c/span\u003e\u003c/p\u003e\n\u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:8.0pt;line-height:107%;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:16px;line-height:107%;\"\u003eTable 3\u003c/span\u003e\u003c/strong\u003e\u003cspan style=\"font-size:16px;line-height:107%;\"\u003e. Clinicopathological characteristics of the HER2+ apocrine cohort (HR+ vs. HR-).\u003c/span\u003e\u003c/p\u003e\n\u003cp\u003e\u003cspan style='font-size:16px;line-height:107%;font-family:\"Calibri\",sans-serif;'\u003e\u003cbr\u003e\u003c/span\u003e\u003cspan style=\"font-size:16px;line-height:107%;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n\u003ctable style=\"border-collapse:collapse;border:none;\"\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 467.5pt;padding: 0in 5.4pt;height: 3pt;vertical-align: top;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"font-size:19px;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003c/tbody\u003e\n\u003c/table\u003e\n\u003ctable style=\"width:500.65pt;border-collapse:collapse;border:none;\"\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 113.4pt;border: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd colspan=\"4\" style=\"width: 192.35pt;border-top: 1pt solid windowtext;border-right: 1pt solid windowtext;border-bottom: 1pt solid windowtext;border-image: initial;border-left: none;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:center;'\u003e\u003cstrong\u003e\u003cspan style=\"color:black;\"\u003eOS\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 17.6pt;border-top: 1pt solid windowtext;border-right: 1pt solid windowtext;border-bottom: 1pt solid windowtext;border-image: initial;border-left: none;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd colspan=\"4\" style=\"width: 177.3pt;border-top: 1pt solid windowtext;border-right: 1pt solid windowtext;border-bottom: 1pt solid windowtext;border-image: initial;border-left: none;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:center;'\u003e\u003cstrong\u003e\u003cspan style=\"color:black;\"\u003eBCSS\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 113.4pt;border-right: 1pt solid windowtext;border-bottom: 1pt solid windowtext;border-left: 1pt solid windowtext;border-image: initial;border-top: none;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 63.8pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:center;'\u003e\u003cspan style=\"color:black;\"\u003eHR\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"2\" style=\"width: 1.15in;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:center;'\u003e\u003cspan style=\"color:black;\"\u003e95% CI\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 45.75pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:center;'\u003e\u003cspan style=\"color:black;\"\u003ep-value\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 17.6pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 45.2pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:center;'\u003e\u003cspan style=\"color:black;\"\u003eHR\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"2\" style=\"width: 85.95pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:center;'\u003e\u003cspan style=\"color:black;\"\u003e95% CI\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 46.15pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:center;'\u003e\u003cspan style=\"color:black;\"\u003ep-value\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 113.4pt;border-right: 1pt solid windowtext;border-bottom: 1pt solid windowtext;border-left: 1pt solid windowtext;border-image: initial;border-top: none;background: rgb(235, 241, 222);padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cstrong\u003e\u003cspan style=\"color:black;\"\u003eHistology\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.8pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;background: rgb(235, 241, 222);padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:center;'\u003e\u003cspan style=\"color:black;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 38.35pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;background: rgb(235, 241, 222);padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"color:black;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 44.45pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;background: rgb(235, 241, 222);padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"color:black;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 45.75pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;background: rgb(235, 241, 222);padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"color:black;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 17.6pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;background: rgb(235, 241, 222);padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"color:black;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 45.2pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;background: rgb(235, 241, 222);padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"color:black;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 44.45pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;background: rgb(235, 241, 222);padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"color:black;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 41.5pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;background: rgb(235, 241, 222);padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"color:black;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 46.15pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;background: rgb(235, 241, 222);padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"color:black;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 113.4pt;border-right: 1pt solid windowtext;border-bottom: 1pt solid windowtext;border-left: 1pt solid windowtext;border-image: initial;border-top: none;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:11.0pt;'\u003e\u003cspan style=\"color:black;\"\u003eApocrine\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.8pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: 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none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 46.15pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 113.4pt;border-right: 1pt solid windowtext;border-bottom: 1pt solid windowtext;border-left: 1pt solid windowtext;border-image: initial;border-top: none;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:11.0pt;'\u003e\u003cspan style=\"color:black;\"\u003eNST\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.8pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cspan style=\"color:black;\"\u003e2.623\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 38.35pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cspan style=\"color:black;\"\u003e1.176\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 44.45pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cspan style=\"color:black;\"\u003e5.848\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 45.75pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cstrong\u003e\u003cspan style=\"color:black;\"\u003e0.018\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 17.6pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 45.2pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cspan style=\"color:black;\"\u003e3.142\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 44.45pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cspan style=\"color:black;\"\u003e1.012\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 41.5pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cspan style=\"color:black;\"\u003e9.763\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 46.15pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cstrong\u003e\u003cspan style=\"color:black;\"\u003e0.047\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 113.4pt;border-right: 1pt solid windowtext;border-bottom: 1pt solid windowtext;border-left: 1pt solid windowtext;border-image: initial;border-top: none;background: rgb(235, 241, 222);padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cstrong\u003e\u003cspan style=\"color:black;\"\u003eAge\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.8pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;background: rgb(235, 241, 222);padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"color:black;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 38.35pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;background: rgb(235, 241, 222);padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"color:black;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 44.45pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;background: rgb(235, 241, 222);padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"color:black;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 45.75pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;background: rgb(235, 241, 222);padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"color:black;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 17.6pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;background: rgb(235, 241, 222);padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"color:black;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 45.2pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;background: rgb(235, 241, 222);padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"color:black;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 44.45pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;background: rgb(235, 241, 222);padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"color:black;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 41.5pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;background: rgb(235, 241, 222);padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"color:black;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 46.15pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;background: rgb(235, 241, 222);padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cstrong\u003e\u003cspan style=\"color:black;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 113.4pt;border-right: 1pt solid windowtext;border-bottom: 1pt solid windowtext;border-left: 1pt solid windowtext;border-image: initial;border-top: none;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:11.0pt;'\u003e\u003cspan style=\"color:black;\"\u003e18-49\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.8pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cspan style=\"color:black;\"\u003e1.000\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 38.35pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 44.45pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 45.75pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 17.6pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 45.2pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cspan style=\"color:black;\"\u003e1.000\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 44.45pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt 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style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:11.0pt;'\u003e\u003cspan style=\"color:black;\"\u003e50-79\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.8pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cspan style=\"color:black;\"\u003e1.551\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 38.35pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp 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style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cspan style=\"color:black;\"\u003e2.152\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 41.5pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cspan style=\"color:black;\"\u003e3.069\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 46.15pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cstrong\u003e\u003cspan style=\"color:black;\"\u003e0.000\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width:113.4pt;border:solid windowtext 1.0pt;border-top:none;background:#EBF1DE;padding:0in 5.4pt 0in 5.4pt;height:.2in;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:13px;color:black;\"\u003eGrade\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.8pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;background: rgb(235, 241, 222);padding: 0in 5.4pt;height: 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style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cspan style=\"color:black;\"\u003e1.000\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 38.35pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 44.45pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 45.75pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 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style=\"color:black;\"\u003e2.704\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 46.15pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cstrong\u003e\u003cspan style=\"color:black;\"\u003e0.000\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width:113.4pt;border:solid windowtext 1.0pt;border-top:none;background:#EBF1DE;padding:0in 5.4pt 0in 5.4pt;height:.2in;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cstrong\u003e\u003cspan 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style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"color:black;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 44.45pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;background: rgb(235, 241, 222);padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"color:black;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 45.75pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;background: rgb(235, 241, 222);padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"color:black;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 17.6pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;background: rgb(235, 241, 222);padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"color:black;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 45.2pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;background: rgb(235, 241, 222);padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"color:black;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 44.45pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;background: rgb(235, 241, 222);padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"color:black;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 41.5pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;background: rgb(235, 241, 222);padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"color:black;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 46.15pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;background: rgb(235, 241, 222);padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cstrong\u003e\u003cspan style=\"color:black;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width:113.4pt;border:solid windowtext 1.0pt;border-top:none;padding:0in 5.4pt 0in 5.4pt;height:.2in;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:10.0pt;'\u003e\u003cspan style=\"font-size:13px;color:black;\"\u003eI\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.8pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cspan style=\"color:black;\"\u003e1.000\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 38.35pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd 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style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cspan style=\"color:black;\"\u003e1.000\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 44.45pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 41.5pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 46.15pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n 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style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cspan style=\"color:black;\"\u003e3.587\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 46.15pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cstrong\u003e\u003cspan style=\"color:black;\"\u003e0.000\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width:113.4pt;border:solid windowtext 1.0pt;border-top:none;padding:0in 5.4pt 0in 5.4pt;height:.2in;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:10.0pt;'\u003e\u003cspan style=\"font-size:13px;color:black;\"\u003eIII\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.8pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cspan style=\"color:black;\"\u003e4.633\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 38.35pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cspan style=\"color:black;\"\u003e4.150\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 44.45pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cspan style=\"color:black;\"\u003e5.172\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 45.75pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cstrong\u003e\u003cspan style=\"color:black;\"\u003e0.000\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 17.6pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 45.2pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cspan style=\"color:black;\"\u003e9.792\u003c/span\u003e\u003c/p\u003e\n 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46.15pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cstrong\u003e\u003cspan style=\"color:black;\"\u003e0.000\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width:113.4pt;border:solid windowtext 1.0pt;border-top:none;padding:0in 5.4pt 0in 5.4pt;height:.2in;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:10.0pt;'\u003e\u003cspan style=\"font-size:13px;color:black;\"\u003eIV\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.8pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cspan style=\"color:black;\"\u003e9.633\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 38.35pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cspan style=\"color:black;\"\u003e8.511\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 44.45pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cspan style=\"color:black;\"\u003e10.903\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 45.75pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cstrong\u003e\u003cspan style=\"color:black;\"\u003e0.000\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 17.6pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 45.2pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cspan style=\"color:black;\"\u003e24.486\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 44.45pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cspan style=\"color:black;\"\u003e20.485\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 41.5pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cspan style=\"color:black;\"\u003e29.267\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 46.15pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cstrong\u003e\u003cspan style=\"color:black;\"\u003e0.000\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width:113.4pt;border:solid windowtext 1.0pt;border-top:none;background:#EBF1DE;padding:0in 5.4pt 0in 5.4pt;height:.2in;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:13px;color:black;\"\u003eTherapy\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.8pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;background: rgb(235, 241, 222);padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"color:black;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 38.35pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;background: rgb(235, 241, 222);padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"color:black;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 44.45pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;background: rgb(235, 241, 222);padding: 0in 5.4pt;height: 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222);padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"color:black;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 45.2pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;background: rgb(235, 241, 222);padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"color:black;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 44.45pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;background: rgb(235, 241, 222);padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"color:black;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 41.5pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;background: rgb(235, 241, 222);padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cspan style=\"color:black;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 46.15pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;background: rgb(235, 241, 222);padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;'\u003e\u003cstrong\u003e\u003cspan style=\"color:black;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width:113.4pt;border:solid windowtext 1.0pt;border-top:none;padding:0in 5.4pt 0in 5.4pt;height:.2in;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:11.0pt;'\u003e\u003cspan style=\"color:black;\"\u003eSurgery (Yes)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.8pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cspan style=\"color:black;\"\u003e0.391\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 38.35pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cspan style=\"color:black;\"\u003e0.355\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 44.45pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp 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\u003ctd style=\"width: 41.5pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cspan style=\"color:black;\"\u003e0.409\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 46.15pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:13px;color:black;\"\u003e0.000\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width:113.4pt;border:solid windowtext 1.0pt;border-top:none;padding:0in 5.4pt 0in 5.4pt;height:.2in;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:11.0pt;'\u003e\u003cspan style=\"color:black;\"\u003eChemotherapy (Yes)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.8pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cspan style=\"color:black;\"\u003e0.419\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 38.35pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cspan style=\"color:black;\"\u003e0.388\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 44.45pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cspan style=\"color:black;\"\u003e0.452\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 45.75pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cstrong\u003e\u003cspan style=\"color:black;\"\u003e0.000\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 17.6pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 45.2pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cspan style=\"color:black;\"\u003e0.425\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 44.45pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cspan style=\"color:black;\"\u003e0.386\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 41.5pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cspan style=\"color:black;\"\u003e0.469\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 46.15pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:13px;color:black;\"\u003e0.000\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width:113.4pt;border:solid windowtext 1.0pt;border-top:none;padding:0in 5.4pt 0in 5.4pt;height:.2in;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-indent:11.0pt;'\u003e\u003cspan style=\"color:black;\"\u003eRadiation (Yes)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 63.8pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cspan style=\"color:black;\"\u003e0.729\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 38.35pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cspan style=\"color:black;\"\u003e0.674\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 44.45pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cspan style=\"color:black;\"\u003e0.787\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 45.75pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cstrong\u003e\u003cspan style=\"color:black;\"\u003e0.000\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 17.6pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 45.2pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cspan style=\"color:black;\"\u003e0.768\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 44.45pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cspan style=\"color:black;\"\u003e0.695\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 41.5pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cspan style=\"color:black;\"\u003e0.847\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 46.15pt;border-top: none;border-left: none;border-bottom: 1pt solid windowtext;border-right: 1pt solid windowtext;padding: 0in 5.4pt;height: 0.2in;vertical-align: bottom;\"\u003e\n \u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:0in;line-height:normal;text-align:right;'\u003e\u003cstrong\u003e\u003cspan style=\"font-size:13px;color:black;\"\u003e0.000\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003c/tbody\u003e\n\u003c/table\u003e\n\u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin:0in;'\u003e\u003cspan style=\"font-size: 13px; color: rgb(0, 0, 0);\"\u003eOS, overall survival; BCSS, breast cancer-specific survival; NST, no special type; HR, hazard ratio; CI, confidence interval.\u003c/span\u003e\u003c/p\u003e\n\u003cp style='margin-right:0in;margin-left:0in;font-size:15px;font-family:\"Calibri\",sans-serif;margin-top:0in;margin-bottom:8.0pt;line-height:107%;'\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cstrong\u003e\u003cspan style=\"font-size:16px;line-height:107%;\"\u003eTable 4\u003c/span\u003e\u003c/strong\u003e\u003c/span\u003e\u003cspan style=\"font-size: 16px; line-height: 107%; color: rgb(0, 0, 0);\"\u003e. Multivariate Cox proportional Hazard analysis of the HER2/HR+/APO vs. HER2/HR+/NST cohorts.\u003c/span\u003e\u003c/p\u003e"}],"fulltextSource":"","fullText":"","funders":[],"hasAdminPriorityOnWorkflow":false,"hasManuscriptDocX":true,"hasOptedInToPreprint":true,"hasPassedJournalQc":"","hasAnyPriority":true,"hideJournal":false,"highlight":"","institution":"","isAcceptedByJournal":true,"isAuthorSuppliedPdf":false,"isDeskRejected":"","isHiddenFromSearch":false,"isInQc":false,"isInWorkflow":false,"isPdf":false,"isPdfUpToDate":true,"isWithdrawnOrRetracted":false,"journal":{"display":true,"email":"[email protected]","identity":"breast-cancer-research-and-treatment","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":false,"externalIdentity":"brea","sideBox":"Learn more about [Breast Cancer Research and Treatment](https://www.springer.com/journal/10549)","snPcode":"10549","submissionUrl":"https://submission.nature.com/new-submission/10549/3","title":"Breast Cancer Research and Treatment","twitterHandle":"","acdcEnabled":true,"dfaEnabled":true,"editorialSystem":"stoa","reportingPortfolio":"Springer Hybrid","inReviewEnabled":true,"inReviewRevisionsEnabled":false},"keywords":"Breast cancer, special types, apocrine carcinoma, HER2, outcome ","lastPublishedDoi":"10.21203/rs.3.rs-1280152/v2","lastPublishedDoiUrl":"https://doi.org/10.21203/rs.3.rs-1280152/v2","license":{"name":"CC BY 4.0","url":"https://creativecommons.org/licenses/by/4.0/"},"manuscriptAbstract":"\u003ch2\u003ePurpose\u003c/h2\u003e \u003cp\u003eApocrine carcinoma of the breast (APO) expresses HER2 in 30-50% of cases. This study explored the clinicopathological features and outcome of HER2+/APO and matched HER2+/NST cohort.\u003c/p\u003e\u003ch2\u003eMethods\u003c/h2\u003e \u003cp\u003eWe used the SEER database to explore the cohorts. Univariate and multivariate analyses were used to assess the survival. Based on ER and PR [=HR] and HER2 status, we divided the cohorts to match the intrinsic molecular subtypes for comparisons.\u003c/p\u003e\u003ch2\u003eResults\u003c/h2\u003e \u003cp\u003eWe retrieved 259 cases of HER2+/APO. Most HER2+/APO were HR negative (65%). HER2+/APO were more prevalent in the 80+ age group (24.7% vs. 15.7%, p\u0026lt;0.001). HER2+/HR-/APO had a significantly lower histological grade than the HER2+/HR-/NST (p\u0026lt;0.001). Breast cancer-related deaths were more prevalent in HER2+/NST (7.8% vs. 3.9%, p=0.019). This was particularly evident between HR- subgroups (10.4% in HER2+/HR-/NST vs. 4.2% in HER2+/HR-/APO, p=0.008) and was reaffirmed in breast cancer-specific survival in univariate analysis (p=0.03). Other than race and HR status, HER2+/APO subgroups did not differ in clinicopathological parameters.\u003c/p\u003e\u003ch2\u003eConclusions\u003c/h2\u003e \u003cp\u003eOur study confirms the rarity of the APO and reveals that HR status in APO does not affect these patients' prognosis. HER2+/APO tumors tend to have a less aggressive phenotype and a more favorable outcome despite a markedly lower ER/PR positivity.\u003c/p\u003e","manuscriptTitle":"HER2-positive Apocrine Carcinoma of the Breast: A population-based Analysis of Treatment and Outcome","msid":"","msnumber":"","nonDraftVersions":[{"code":2,"date":"2022-02-21 14:57:42","doi":"10.21203/rs.3.rs-1280152/v2","editorialEvents":[{"type":"communityComments","content":0},{"type":"decision","content":"Minor Revisions Needed","date":"2022-03-12T15:18:58+00:00","index":"","fulltext":""},{"type":"editorInvitedReview","content":"","date":"2022-02-10T09:37:38+00:00","index":0,"fulltext":""},{"type":"editorAssigned","content":"","date":"2022-02-09T11:18:24+00:00","index":"","fulltext":""},{"type":"submitted","content":"Breast Cancer Research and Treatment","date":"2022-02-05T22:18:15+00:00","index":"","fulltext":""}],"status":"published","journal":{"display":true,"email":"[email protected]","identity":"breast-cancer-research-and-treatment","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":false,"externalIdentity":"brea","sideBox":"Learn more about [Breast Cancer Research and Treatment](https://www.springer.com/journal/10549)","snPcode":"10549","submissionUrl":"https://submission.nature.com/new-submission/10549/3","title":"Breast Cancer Research and Treatment","twitterHandle":"","acdcEnabled":true,"dfaEnabled":true,"editorialSystem":"stoa","reportingPortfolio":"Springer Hybrid","inReviewEnabled":true,"inReviewRevisionsEnabled":false}}],"origin":"","ownerIdentity":"89bfcdc3-3a19-45c1-8dd8-12dc0c46b768","owner":[],"postedDate":"February 21st, 2022","published":true,"recentEditorialEvents":[],"rejectedJournal":[],"revision":"","amendment":"","status":"under-review","subjectAreas":[],"tags":[],"updatedAt":"2022-03-17T15:45:45+00:00","versionOfRecord":[],"versionCreatedAt":"2022-02-21 14:57:42","video":"","vorDoi":"","vorDoiUrl":"","workflowStages":[]},"version":"v2","identity":"rs-1280152","journalConfig":"researchsquare"},"__N_SSP":true},"page":"/article/[identity]/[[...version]]","query":{"redirect":"/article/rs-1280152","identity":"rs-1280152","version":["v2"]},"buildId":"wLkW0s4AflPzk-lpfg-fK","isFallback":false,"isExperimentalCompile":false,"dynamicIds":[84888],"gssp":true,"scriptLoader":[]}