Hoch sensibles CRP im Vergleich zu CRP als Laborparameter bei Endometriosepatientinnen
This study compared hs-CRP and CRP as diagnostic markers for endometriosis, finding no significant advantage for either, although very low hs-CRP suggests a lower likelihood of endometriosis.
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The study compared high-sensitivity CRP (hs-CRP) and conventional CRP as potential diagnostic serum markers for endometriosis in 164 women with suspected disease. CRP and hs-CRP were measured, with 82 women undergoing laparoscopy (34 without endometriosis and 48 with histologically confirmed endometriosis), and 82 additional non-operated women serving as an “unknown endometriosis” control group; in the confirmed cohort, disease stage was classified using revised ASRM criteria. CRP and hs-CRP showed a trend toward higher values in the histologically confirmed endometriosis group and lowest values in the non-endometriosis group, but there was no significant diagnostic advantage for either marker and no correlation between marker levels and disease stage. The authors conclude that a very low hs-CRP makes endometriosis less likely. This paper is centrally about endometriosis — it evaluates hs-CRP versus CRP for diagnostic performance and examines relationships with endometriosis stage.
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