Developing a Model for the Success of Healthcare Start-up Companies in Iran: A Systematic Review and Interviews with Experts

Developing a Model for the Success of Healthcare Start-up Companies in Iran: A Systematic Review and Interviews with Experts | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Research Article Developing a Model for the Success of Healthcare Start-up Companies in Iran: A Systematic Review and Interviews with Experts Navid Majedi, Mohammad Meskarpour-Amiri, Maryam Yaghoubi This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-4296101/v1 This work is licensed under a CC BY 4.0 License Status: Posted Version 1 posted You are reading this latest preprint version Abstract Background: In the dynamic landscape of healthcare, start-ups drive transformative change. Understanding the pivotal factors influencing their success is paramount to their advancement. This study aims to present a comprehensive framework delineating the drivers of success for emerging businesses in healthcare. Methods: Employing a mixed-method approach, this research integrates expert interviews and a systematic review of pertinent literature. Extensive scientific exploration across databases, augmented by manual searches and expert surveys, identified 57 influential factors from 37 selected articles and interviews. Through expert consultations, additional factors were incorporated, culminating in an 11-dimensional classification. Finally, the position of the factors in 4 stages (before starting the business, during the activity, evaluation, control and feedback) was determined, and the final model was extracted. Results: Based on the inclusion and exclusion criteria, a total of 37 articles were reviewed. Eleven dimensions were utilized to classify the 57 factors identified in this study. The factors "choosing the appropriate marketing and advertising strategy" and "targeting how to finance the business" had the highest number of repetitions in the studies; 49% of these factors were related to the stage "before starting the business", and 33% were related to "during activity". Discussion : To ensure growth and development at various stages of business formation, founders of start-up businesses in the healthcare sector need to carefully consider the factors that impact success, particularly business financing and marketing and advertising strategies. Growth and Development HealthCare Sector marketing Full Text Additional Declarations No competing interests reported. Cite Share Download PDF Status: Posted Version 1 posted You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. Our growing team is made up of researchers and industry professionals working together to solve the most critical problems facing scientific publishing. Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-4296101","acceptedTermsAndConditions":true,"allowDirectSubmit":true,"archivedVersions":[],"articleType":"Research Article","associatedPublications":[],"authors":[{"id":295244425,"identity":"bc0fbce4-cd81-4d38-9a3c-14cef1ebbbc1","order_by":0,"name":"Navid Majedi","email":"","orcid":"","institution":"Allameh Tabataba'i University","correspondingAuthor":false,"prefix":"","firstName":"Navid","middleName":"","lastName":"Majedi","suffix":""},{"id":295244426,"identity":"83ed03f3-e464-4be7-b9f1-4fc1169b88b5","order_by":1,"name":"Mohammad Meskarpour-Amiri","email":"","orcid":"","institution":"Baqiyatallah University of Medical Sciences","correspondingAuthor":false,"prefix":"","firstName":"Mohammad","middleName":"","lastName":"Meskarpour-Amiri","suffix":""},{"id":295244427,"identity":"d39b67ac-15bd-49db-aacc-27cadc850eef","order_by":2,"name":"Maryam Yaghoubi","email":"data:image/png;base64,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","orcid":"","institution":"Baqiyatallah University of Medical Sciences","correspondingAuthor":true,"prefix":"","firstName":"Maryam","middleName":"","lastName":"Yaghoubi","suffix":""}],"badges":[],"createdAt":"2024-04-20 06:24:06","currentVersionCode":1,"declarations":"","doi":"10.21203/rs.3.rs-4296101/v1","doiUrl":"https://doi.org/10.21203/rs.3.rs-4296101/v1","draftVersion":[],"editorialEvents":[],"editorialNote":"","failedWorkflow":false,"files":[{"id":108990491,"identity":"97c63207-33cc-4dd6-912c-bc069029aabf","added_by":"auto","created_at":"2026-05-11 13:19:43","extension":"pdf","order_by":1,"title":"","display":"","copyAsset":false,"role":"manuscript-pdf","size":462175,"visible":true,"origin":"","legend":"","description":"","filename":"manuscript.pdf","url":"https://assets-eu.researchsquare.com/files/rs-4296101/v1_covered_1572cf30-c908-4bf3-87ac-a9965ffc9061.pdf"}],"financialInterests":"No competing interests reported.","formattedTitle":"Developing a Model for the Success of Healthcare Start-up Companies in Iran: A Systematic Review and Interviews with Experts","fulltext":[],"fulltextSource":"","fullText":"","funders":[],"hasAdminPriorityOnWorkflow":false,"hasManuscriptDocX":false,"hasOptedInToPreprint":true,"hasPassedJournalQc":"","hasAnyPriority":false,"hideJournal":true,"highlight":"","institution":"","isAcceptedByJournal":false,"isAuthorSuppliedPdf":true,"isDeskRejected":"","isHiddenFromSearch":false,"isInQc":false,"isInWorkflow":false,"isPdf":true,"isPdfUpToDate":true,"isWithdrawnOrRetracted":false,"journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true},"keywords":"Growth and Development, HealthCare Sector, marketing","lastPublishedDoi":"10.21203/rs.3.rs-4296101/v1","lastPublishedDoiUrl":"https://doi.org/10.21203/rs.3.rs-4296101/v1","license":{"name":"CC BY 4.0","url":"https://creativecommons.org/licenses/by/4.0/"},"manuscriptAbstract":"\u003cp\u003e\u003cstrong\u003eBackground:\u003c/strong\u003e In the dynamic landscape of healthcare, start-ups drive transformative change. Understanding the pivotal factors influencing their success is paramount to their advancement. This study aims to present a comprehensive framework delineating the drivers of success for emerging businesses in healthcare.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eMethods:\u003c/strong\u003e Employing a mixed-method approach, this research integrates expert interviews and a systematic review of pertinent literature. Extensive scientific exploration across databases, augmented by manual searches and expert surveys, identified 57 influential factors from 37 selected articles and interviews. Through expert consultations, additional factors were incorporated, culminating in an 11-dimensional classification. Finally, the position of the factors in 4 stages (before starting the business, during the activity, evaluation, control and feedback) was determined, and the final model was extracted.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eResults:\u003c/strong\u003e Based on the inclusion and exclusion criteria, a total of 37 articles were reviewed. Eleven dimensions were utilized to classify the 57 factors identified in this study. 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