Establishment of a risk prediction model for bowel preparation failure prior to colonoscopy

Background: This study aimed to determine the factors that contribute to the failure of bowel preparation in patients undergoing colonoscopy and to develop a risk prediction model. Methods: A total of 1115 patients were included. Patients were randomly divided into two groups: the modeling group (669 patients) and the validation group (446 patients). In the modeling group, patients were further divided into two groups based on their success and failure in bowel preparation using the Boston bowel preparation scale. Results: After controlling for relevant confounders, multifactorial logistic regression results showed that age ≥60 years (OR= 2.246), male (OR= 2.449), body mass index ≥ 24 (OR= 2.311), smoking (OR= 2.467), chronic constipation (OR= 5.199), diabetes mellitus (OR= 5.396) and history of colorectal surgery ( OR = 5.170) were influencing factors of bowel preparation failure. The area under the ROC curve was 0.732 in the modeling group and 0.713 in the validation group. Conclusions: According to the calibration plot, the predictive effect of the model and the actual results were in good agreement. Age ≥60 years, male, body mass index ≥ 24, smoking, chronic constipation, diabetes mellitus, and history of colorectal surgery are independent risk factors for bowel preparation failure. The established prediction model has a good predictive efficacy and can be used as a clinical screening tool.