A Retrospective, Clinical Study To Evaluate The IOL Tilt And Decentration Of Two Different Hydrophobic Aspheric Monofocal Intraocular Lenses. 

Purpose: To evaluate the clinical performance of two monofocal aspheric intraocular lenses (IOLs) to determine their position in the capsular bag after the implantation. Methods: This retrospective study collates data from the medical records of patients who were diagnosed with cataract, underwent cataract surgery, implanted with two different hydrophobic aspheric monofocal IOL. A total of 6 visit data were considered in the study, out of which four follow-up visits were on day 1, day 7, day 30, and day 180 after the completion of cataract surgery. The investigational variables included IOL tilt and IOL decentration, uncorrected and best corrected visual acuity (UCVA and BCVA), contrast sensitivity, manifest refraction, intraocular pressure, posterior capsule opacification and overall safety Results: A total of 85 subjects’ medical records were screened, out of which 43 subjects’ medical records were enrolled in IOL 1 arm and 42 subjects’ medical records were enrolled in IOL 2 arm. Moreover, 13 (30.23%), and 6 (14.29%) subjects discontinued the study due to lost to follow-up in IOL 1 and IOL 2 arm, respectively. There were no statistically significant differences (p > 0.05) in vertical and horizontal IOL tilt and decentration results between IOL 1 arm and IOL 2 arm. Within-group analysis using paired t-test, a significant difference (p  0.05) at all visits in BCVA between IOL 1 and IOL 2 arms. Conclusion: IOL vertical and horizontal tilt and decentration found in the current study are within the limits reported in the literature and in the between-group analysis there were no significant differences in IOL 1 and IOL 2.