GENLIB: new function to simulate haplotype transmission in large complex genealogies
preprint
OA: closed
CC-BY-4.0
Abstract
Summary Founder populations with deep genealogical data are well suited for investigating genetic variants contributing to diseases. Here, we present a new function added to the genealogical analysis R package GENLIB, which can simulate the transmission of haplotypes from founders to probands along very large and complex user-specified genealogies. Availability and implementation The new function is available in the latest version of the GENLIB package (v1.1.6), available on the CRAN repository and from https://github.com/R-GENLIB/GENLIB . Stand-alone scripts for analyzing the output of the function can be accessed at https://github.com/R-GENLIB/simuhaplo_scripts .
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- europepmc
- last seen: 2026-05-19T01:45:01.086888+00:00
- unpaywall
- last seen: 2026-05-28T02:00:01.590549+00:00
License: CC-BY-4.0