Treating refractory thin endometrium through a novel way of activation and administration of Platelet-rich plasma in sexually active women: An interventional prospective cohort clinical study
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Platelet-rich plasma infusion improved endometrial thickness and pregnancy rates in women with refractory thin endometrium, with lower AMH levels predicting a greater need for treatment.
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Abstract
A prospective cohort study investigated the effectiveness of platelet-rich plasma (PRP) infusion for refractory thin endometrium in 38 infertile patients. Patients showed significant improvement in endometrial thickness post-PRP injection, leading to successful implantation and pregnancy. The study revealed a negative correlation between antimullerian hormone (AMH) levels and the need for PRP interventions, suggesting higher ovarian reserve may reduce the necessity for repeated treatments. This implies AMH levels could serve as a prognostic indicator for treatment outcomes, aiding clinicians in optimizing protocols and reducing patient burden. Further research is needed to confirm these findings in larger and more diverse populations, along with exploring long-term reproductive success rates post-PRP treatment.
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Cites (3)
- Physiology of the Endometrium and Regulation of Menstruation 2020
- Endometrial growth and uterine blood flow: a pilot study for improving endometrial thickness in the patients with a thin endometrium 2009
- Extended estrogen administration for women with thin endometrium in frozen-thawed in-vitro fertilization programs 2006
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Cited by (1)
SciLite annotations
chemicals 6
estrogen
vitamin e
sildenafil
diethylcarbamazine citrate
carbonate mineral
carbonate mineral
Source provenance
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- scilite
- last seen: 2026-05-18T04:57:49.680383+00:00
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