Corneal histopathology in Stevens-Johnson syndrome: A case report and review of literature

Abstract Stevens-Johnson syndrome is a life-threatening, immune-mediated, acute inflammatory disorder of the mucocutaneous membranes. It affects people of almost any age and has a high mortality and morbidity rate. Therefore, histopathological confirmation of the diagnosis is essential. Ocular involvement occurs in more than 50% of the affected patients. Here, we report a case of Stevens-Johnson syndrome with ocular involvement in a 10-year old boy that presented with complaints of pain, burning, stinging in both eyes, and decreased vision. Histopathological findings were consistent with the changes due to the syndrome. Stevens-Johnson syndrome affects various mucous membranes along with the skin. Ocular involvement may manifest both acutely and chronically and causes morbidities. Therefore, a careful clinical and histopathologic examination is required in order to give the correct diagnosis.