Uterine Adenocarcinoma with Pulmonary, Liver and Mesentery Metastasis in a Holstein Cow

Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The clinical and pathology features of a cow with uterine adenocarcinoma and multiple metastasis are described. Weight loss, inappetence, mild respiratory signs, and reduced milk yield were evident on clinical examination. Grossly deformed uterus, enlarged iliac lymph nodes, and rosary arranged nodules in the mesentery were felt by rectal palpation. Right side laparotomy revealed numerous small masses covering the omentum, and mesentery. Euthanasia was performed. Necropsy and histopathology exam revealed a uterine adenocarcinoma with multiple pulmonary, liver and mesentery metastasis. Uterine adenocarcinoma with metastasis should be included in the differential diagnosis of cows showing weight loss and mild respiratory distress and palpation of numerous firm nodules in the mesentery should be suggestive of neoplasias ’ metastasis. 1. Case Description A 5.5-year-old Holstein cow was presented in May 2008 for clinical examination because of inappetence and milk and weight loss over a two-week period. The cow had calved three times and the last calving was in November 2007. In March 2008 the cow was found in heat and was inseminated without