SUPERACTIVE GONADOTROPIN-REL EASING HORMONE AGONISTS

Ronald S. Swerdloff, David Heber
1983 · W2183676630
article OA: closed CC0 Metadata only
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Abstract

Superactive GnRH agonists represent a new class of pharmacologic agents that inhibit reproductive function in both men and women when adminis­ tered chronically. These hormonal drugs are being tested extensively as both male and female contraceptive agents, as a treatment for prostate cancer, and as a new treatment for idiopathic precocious puberty. Other potential uses include treatment for endometriosis, hirsutism, polycystic ovarian disease, and severe intractable androgen-related acne. This chapter reviews the effects of GnRH agonists on gonadotropin and steroid hormone secretion in both men and women, and assesses the potential of these agents in the varied clinical uses delineated above.

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endometriosis

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