Efficacy of an oral contraceptive containing 0.030mg ethinylestradiol and 2mg dienogest (EE/DNG) for the treatment of acne – Comparison with placebo and with 0.035mg ethinylestradiol / 2mg cyproterone acetate (EE/CPA)

In: Geburtshilfe und Frauenheilkunde · 2008 · vol. 68(S 01) · doi:10.1055/s-0028-1089030 · W2320529667
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Abstract

Introduction: Papulopustular acne is a common skin disease characterized, beside other factors, by androgenic stimulation of sebaceous glands. Combined oral contraceptives (COC) containing progestins with anti-androgenic properties (including e.g. dienogest [DNG]) are therefore suitable for the treatment of acne. The aim of this study was to show the non-inferiority of EE/DNG compared to EE/CPA (a well-established hormonal anti-acne treatment), and the superiority of EE/DNG compared to placebo.

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