Trends in COVID-19 Publications: Streamlining Research Using NLP and LDA

Research publications related to the novel coronavirus disease COVID-19 are rapidly growing in number. However, current online literature hubs, even with artificial intelligence, are inadequate for identifying the relative strength of research topics. Hence, we aimed to develop a comprehensive Latent Dirichlet Allocation (LDA) topic model using natural language processing (NLP) techniques, provide visualisations for temporal trends, and apply our methodology to improve existing online literature hubs.Using the search term “COVID”, abstracts were extracted from PubMed®, from January to July 2020 (N=16346). An LDA topic model was trained on 81% of abstracts. Weekly temporal trends were visualised as a heatmap on all abstracts. Then, we tested our methodology on over 23,000 abstracts gathered from January 2020 to September 2020 from LitCovid, a literature hub from the National Center for Biotechnology Information. We use our topic model to subdivide LitCovid’s eight categories into corresponding LDA topics.The optimised LDA topic model, created using PubMed® data, produced 25 comprehensive topics with no significant overlap. There were temporal changes for topics: prominence of “Mental Health” and “Socioeconomic Impact” increased, “Genome Sequence” decreased, and “Epidemiology” remained relatively constant. We identified inadequate representation of “Airborne Transmission Protection”. Importantly, research on masks and PPE is skewed towards clinical applications with a lack of population-based epidemiological research. Our methodology, when applied to LitCovid, identified important topics within each LitCovid category. For example, “Case Report” was split into topics such as “Pulmonary” and “Oncology” as well as the under-represented topics “Haematology” and “Gastroenterology”. Our work allows for comprehensive topic identification and intuitive visualisation of temporal trends in COVID-19 research. Implementation of the methodology complements existing online literature hubs and identifies underrepresented topics such as population-based studies on masks that may be of significant public interest.Funding Statement: None to declare.Declaration of Interests: There are no conflicts of interest.