FIThe Effects of Curcumin Supplementation on Body Weight, Body Mass Index, and Waist Circumference in Patients with Type 2 Diabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

The study investigates the effects of curcumin on obesity and its related factors in diabetic patients, given that obesity can lead to insulin resistance and complicate diabetes management. An analysis of nine randomized controlled trials (RCTs) involving 699 participants was conducted to evaluate curcumin’s impact on body weight (BW), body mass index (BMI), and waist circumference (WC). The results indicated a significant reduction in BW (WMD: −1.65 kg), BMI (WMD: −0.69 kg/m2), and WC (WMD: - 0.93 cm) with curcumin consumption compared to controls. Higher doses of curcumin (>1000 mg/day) were notably more effective in reducing BW, BMI, and WC than lower doses. The study concludes that curcumin supplementation effectively reduces BW, BMI, and WC in diabetic patients, especially at higher doses, and suggests the need for further studies to explore these benefits.