The Comparison of Ultrasound and Fluoroscopy-guided for Determining Puncture Entry Point of Percutaneous Vertebroplasty

The Comparison of Ultrasound and Fluoroscopy-guided for Determining Puncture Entry Point of Percutaneous Vertebroplasty | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Research The Comparison of Ultrasound and Fluoroscopy-guided for Determining Puncture Entry Point of Percutaneous Vertebroplasty Sen Ye, Xiaorong Lai, Lingjian Zhong, Changzhang Yu, Yanzhen Chen This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-149179/v1 This work is licensed under a CC BY 4.0 License Status: Posted Version 1 posted You are reading this latest preprint version Abstract OBJECTIVE : The purpose of this study was to compare the safety and efficacy of ultrasound and fluoroscopy-guided for determining the puncture entry point of percutaneous vertebroplasty (PVP). Methods : From November 2018 to December 2019, a total of 50 eligible patients with thoracolumbar osteoporotic vertebral compression fractures (OVCFs) treated by PVP were retrospectively collected, of which 25 cases were in ultrasound-guided group and the other 25 cases were in fluoroscopy-guided group. Radiation doses, one-time localization success rate, operation time, clinical efficacy and complications incidence were compared between the two groups. Results : Ultimately, 46 patients completed followed-up, whose average follow-up time was 9 months, the dose and times of fluoroscopy and operation time in ultrasound-guided group statically significantly decreased compared with fluoroscopy-guided group (P<0.01). The one-time localization success rate in ultrasound-guided group and fluoroscopy-guided group were 68.2% and 37.5% respectively ( x 2 = 4.33, P=0.037), whose difference was statistically significant (P0.05). There were no postoperative complications such as infection, hematoma formation and fracture nonunion observed between the two groups. Conclusion : Ultrasound-guided entry point determination for PVP puncture is safe, which can significantly improve the success rate of one-time localization and decrease radiation exposure and operation time. Health Economics & Outcomes Research Medical Genetics Ultrasound-guided fluoroscopy-guided puncture entry point percutaneous vertebroplasty osteoporotic vertebral compression fracture Figures Figure 1 Figure 2 Figure 3 Figure 4 Full Text Due to technical limitations, full-text HTML conversion of this manuscript could not be completed. However, the latest manuscript can be downloaded and accessed as a PDF. Tables Due to technical limitations, tables are only available as a download in the Supplemental Files section. Supplementary Files Table.pdf Cite Share Download PDF Status: Posted Version 1 posted You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. Our growing team is made up of researchers and industry professionals working together to solve the most critical problems facing scientific publishing. Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-149179","acceptedTermsAndConditions":true,"allowDirectSubmit":true,"archivedVersions":[],"articleType":"Research","associatedPublications":[],"authors":[{"id":8375832,"identity":"882d20c4-e9e4-47ff-825a-e7585f036fa5","order_by":0,"name":"Sen Ye","email":"data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAZAAAAAyAQMAAABI0h/eAAAABlBMVEX///8AAABVwtN+AAAACXBIWXMAAA7EAAAOxAGVKw4bAAAA0klEQVRIiWNgGAWjYBADHgYG5gMMCSRqYUsgTQtIlwFx6gyOtz98XPDnjow5e8/nDw932DHwz24goOXMGWPjmW3PeCx7zm6TSDyTzCBx5wABLTdy2KR5Gw7zGNzI3caQ2MbMYCCRQEDL/efPf/P8AWq5/+bxh8S2eiK03GAwY+ZhA9nCwyCR2HaYsBbJMznG0rxAvxicSTMDajnOI3GDgBa+48cffub5c8fe4Pjhxx9/tlXL8c8goEXhAJg6ABfgwa8eCOQb0LSMglEwCkbBKMAAAFuLRncW/k0eAAAAAElFTkSuQmCC","orcid":"https://orcid.org/0000-0003-3864-367X","institution":"The First Affiliated Hospital of Chongqing Medical University","correspondingAuthor":true,"submittingAuthor":false,"prefix":"","firstName":"Sen","middleName":"","lastName":"Ye","suffix":""},{"id":8375833,"identity":"1c586298-535e-4e35-9abd-71bd2d27ea43","order_by":1,"name":"Xiaorong Lai","email":"","orcid":"","institution":"The First Affiliated Hospital of Chongqing Medical University","correspondingAuthor":false,"submittingAuthor":false,"prefix":"","firstName":"Xiaorong","middleName":"","lastName":"Lai","suffix":""},{"id":8375834,"identity":"377649ad-230d-4230-b8a2-0d9a7567f0e1","order_by":2,"name":"Lingjian Zhong","email":"","orcid":"","institution":"The First Affiliated Hospital of Chongqing Medical University","correspondingAuthor":false,"submittingAuthor":false,"prefix":"","firstName":"Lingjian","middleName":"","lastName":"Zhong","suffix":""},{"id":8375835,"identity":"e7b5cd59-e48f-4cf8-88f5-36e33acaa24b","order_by":3,"name":"Changzhang Yu","email":"","orcid":"","institution":"The First Affiliated Hospital of Chongqing Medical University","correspondingAuthor":false,"submittingAuthor":false,"prefix":"","firstName":"Changzhang","middleName":"","lastName":"Yu","suffix":""},{"id":8375836,"identity":"0ab6cf70-a4ef-4237-a5bb-f4a03ae366e7","order_by":4,"name":"Yanzhen Chen","email":"","orcid":"","institution":"The First Affiliated Hospital of Chongqing Medical University","correspondingAuthor":false,"submittingAuthor":false,"prefix":"","firstName":"Yanzhen","middleName":"","lastName":"Chen","suffix":""}],"badges":[],"createdAt":"2021-01-16 23:36:56","currentVersionCode":1,"declarations":"","doi":"10.21203/rs.3.rs-149179/v1","doiUrl":"https://doi.org/10.21203/rs.3.rs-149179/v1","draftVersion":[],"editorialEvents":[],"editorialNote":"","failedWorkflow":false,"files":[{"id":5096056,"identity":"984a98c8-46bb-4078-8517-2867560deb78","added_by":"auto","created_at":"2021-01-19 19:15:37","extension":"jpg","order_by":1,"title":"Figure 1","display":"","copyAsset":false,"role":"figure","size":64875,"visible":true,"origin":"","legend":"Sagittal section of transverse process","description":"","filename":"1.jpg","url":"https://assets-eu.researchsquare.com/files/rs-149179/v1/3167cc6ab7c2142a3be428f1.jpg"},{"id":5096171,"identity":"4526bec3-639c-4676-8eeb-ec40f4099e73","added_by":"auto","created_at":"2021-01-19 19:18:37","extension":"jpg","order_by":2,"title":"Figure 2","display":"","copyAsset":false,"role":"figure","size":76604,"visible":true,"origin":"","legend":" That was the vertical \nspinal muscle, transverse process, intertransverse process and the psoas major muscle. \nThis imaging was described as a \"Trident\" sign） \n ","description":"","filename":"2.jpg","url":"https://assets-eu.researchsquare.com/files/rs-149179/v1/4e9cdcc3e9f7959d7b5a0875.jpg"},{"id":5096173,"identity":"9125e82c-c55e-4462-9174-c367785f4516","added_by":"auto","created_at":"2021-01-19 19:18:38","extension":"jpg","order_by":3,"title":"Figure 3","display":"","copyAsset":false,"role":"figure","size":57679,"visible":true,"origin":"","legend":"Cross section of herringbone crest","description":"","filename":"3.jpg","url":"https://assets-eu.researchsquare.com/files/rs-149179/v1/00e72c8eee8688cf95884985.jpg"},{"id":5096172,"identity":"44edc65a-946c-45f1-bdf8-2052ffc98ac3","added_by":"auto","created_at":"2021-01-19 19:18:37","extension":"jpg","order_by":4,"title":"Figure 4","display":"","copyAsset":false,"role":"figure","size":59068,"visible":true,"origin":"","legend":"When the convex part of \nthe superior articular process disappeared, the \"inverted triangle\"-shaped soft tissue \nacoustic image below it could be seen, which was the vertex of the herringbone ridge \nand the puncture location. Spinous process(SP), herringbone ridge(HR)） ","description":"","filename":"4.jpg","url":"https://assets-eu.researchsquare.com/files/rs-149179/v1/b17abe2c81600d687f769664.jpg"},{"id":13577084,"identity":"e1bcb2d1-be6f-409a-9149-c3635bf783d3","added_by":"auto","created_at":"2021-09-17 04:10:14","extension":"pdf","order_by":1,"title":"","display":"","copyAsset":false,"role":"manuscript-pdf","size":585611,"visible":true,"origin":"","legend":"","description":"","filename":"manuscriptM.pdf","url":"https://assets-eu.researchsquare.com/files/rs-149179/v1_covered.pdf"},{"id":5096352,"identity":"21401714-2eb5-46e3-a756-601fccfb991a","added_by":"auto","created_at":"2021-01-19 19:21:42","extension":"pdf","order_by":1,"title":"","display":"","copyAsset":false,"role":"manuscript-pdf","size":1037301,"visible":true,"origin":"","legend":"","description":"","filename":"manuscriptM.pdf","url":"https://assets-eu.researchsquare.com/files/rs-149179/v1_stamped.pdf"},{"id":5096174,"identity":"0ed90279-a678-4ec0-bb15-bb36a992f9af","added_by":"auto","created_at":"2021-01-19 19:18:38","extension":"pdf","order_by":1,"title":"","display":"","copyAsset":false,"role":"supplement","size":242491,"visible":true,"origin":"","legend":"","description":"","filename":"Table.pdf","url":"https://assets-eu.researchsquare.com/files/rs-149179/v1/a774e27a3e8fc6a6db3f975a.pdf"}],"financialInterests":"","formattedTitle":"\u003cp\u003eThe Comparison of Ultrasound and Fluoroscopy-guided for Determining Puncture Entry Point of Percutaneous Vertebroplasty\u003c/p\u003e","fulltext":[{"header":"Full Text","content":"Due to technical limitations, full-text HTML conversion of this manuscript could not be completed. However, the latest manuscript can be downloaded and \u003ca href='/article/rs-149179/latest.pdf' target='_blank'\u003e accessed as a PDF.\u003c/a\u003e"},{"header":"Tables","content":"\u003cp\u003eDue to technical limitations, tables are only available as a download in the Supplemental Files section.\u003c/p\u003e"}],"fulltextSource":"","fullText":"","funders":[],"hasAdminPriorityOnWorkflow":false,"hasManuscriptDocX":false,"hasOptedInToPreprint":true,"hasPassedJournalQc":"","hasAnyPriority":false,"hideJournal":true,"highlight":"","institution":"","isAcceptedByJournal":false,"isAuthorSuppliedPdf":true,"isDeskRejected":"","isHiddenFromSearch":false,"isInQc":false,"isInWorkflow":false,"isPdf":false,"isPdfUpToDate":true,"isWithdrawnOrRetracted":false,"journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true},"keywords":"Ultrasound-guided, fluoroscopy-guided, puncture entry point percutaneous vertebroplasty, osteoporotic vertebral compression fracture ","lastPublishedDoi":"10.21203/rs.3.rs-149179/v1","lastPublishedDoiUrl":"https://doi.org/10.21203/rs.3.rs-149179/v1","license":{"name":"CC BY 4.0","url":"https://creativecommons.org/licenses/by/4.0/"},"manuscriptAbstract":"\u003cp\u003e\u003cstrong\u003eOBJECTIVE\u003c/strong\u003e: The purpose of this study was to compare the safety and efficacy of ultrasound and fluoroscopy-guided for determining the puncture entry point of percutaneous vertebroplasty (PVP). \u003c/p\u003e\u003cp\u003e\u003cstrong\u003eMethods\u003c/strong\u003e: From November 2018 to December 2019, a total of 50 eligible patients with thoracolumbar osteoporotic vertebral compression fractures (OVCFs) treated by PVP were retrospectively collected, of which 25 cases were in ultrasound-guided group and the other 25 cases were in fluoroscopy-guided group. Radiation doses, one-time localization success rate, operation time, clinical efficacy and complications incidence were compared between the two groups. \u003c/p\u003e\u003cp\u003e\u003cstrong\u003eResults\u003c/strong\u003e: Ultimately, 46 patients completed followed-up, whose average follow-up time was 9 months, the dose and times of fluoroscopy and operation time in ultrasound-guided group statically significantly decreased compared with fluoroscopy-guided group (P\u0026lt;0.01). The one-time localization success rate in ultrasound-guided group and fluoroscopy-guided group were 68.2% and 37.5% respectively ( x 2 = 4.33, P=0.037), whose difference was statistically significant (P\u0026lt;0.01). However, there was no significant difference in the visual analog scale (VAS) scores of back pain relief between the two groups (P\u0026gt;0.05). There were no postoperative complications such as infection, hematoma formation and fracture nonunion observed between the two groups.\u003c/p\u003e\u003cp\u003e\u003cstrong\u003eConclusion\u003c/strong\u003e: Ultrasound-guided entry point determination for PVP puncture is safe, which can significantly improve the success rate of one-time localization and decrease radiation exposure and operation time.\u003c/p\u003e","manuscriptTitle":"The Comparison of Ultrasound and Fluoroscopy-guided for Determining Puncture Entry Point of Percutaneous Vertebroplasty","msid":"","msnumber":"","nonDraftVersions":[{"code":1,"date":"2021-01-19 19:15:36","doi":"10.21203/rs.3.rs-149179/v1","editorialEvents":[{"type":"communityComments","content":0}],"status":"published","journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true}}],"origin":"","ownerIdentity":"45b60489-7a86-4e8f-a03c-72f66662af01","owner":[],"postedDate":"January 19th, 2021","published":true,"recentEditorialEvents":[],"rejectedJournal":[],"revision":"","amendment":"","status":"posted","subjectAreas":[{"id":1961863,"name":"Health Economics \u0026 Outcomes Research"},{"id":1961864,"name":"Medical Genetics"}],"tags":[],"updatedAt":"2021-03-21T13:29:39+00:00","versionOfRecord":[],"versionCreatedAt":"2021-01-19 19:15:36","video":"","vorDoi":"","vorDoiUrl":"","workflowStages":[]},"version":"v1","identity":"rs-149179","journalConfig":"researchsquare"},"__N_SSP":true},"page":"/article/[identity]/[[...version]]","query":{"redirect":"/article/rs-149179","identity":"rs-149179","version":["v1"]},"buildId":"7rjqhiLT3MXkJMwkYKINL","isFallback":false,"isExperimentalCompile":false,"dynamicIds":[84888],"gssp":true,"scriptLoader":[]}