Alpha- and beta-diversity analyses.

Alpha- and beta-diversity plots to visualize the difference in bacterial microbiota structure between endometriosis and sham (control) groups 3 days before the induction of endometriosis (before EI; endometriosis: n = 8, sham: n = 6) as well as on days 7 (endometriosis: n = 8, sham: n = 8) and 21 (endometriosis: n = 5, sham: n = 7) after the induction of endometriosis (after EI). Shown are alpha- diversity measures with the most common indices (A) and PCoA plots showing the beta-diversity with unweighted (B) and weighted (C) unifrac measures. Box plots (A) show median as well as lower and upper quartiles. Whiskers represent minimum and maximum spread. PCoA plots (B and C) show dimensions with the highest differences and normal confidence ellipses for the sample sets.