Diminution of Liver Aminotransferase Enzymes Levels in Nonalcoholic Fatty Liver Disease by Silymarin: A Case Report

Abstract This article reports the case of a woman with chief complains of aching pain in the upper right of her abdomen, fatigue, and weakness. She had no medical history of any diseases, trauma, and other signs related to her complains. Both blood tests and abdominal ultrasonography revealed that she has been afflicted with nonalcoholic fatty liver disease (NAFLD). The medical procedure consisted of administering a polyphenolic flavonoid named silymarin, which have been pointed out that it has antioxidant, anti-fibrotic, and anti-inflammatory properties. After taking 30 days silymarin, her liver aminotransferase enzymes levels including alanine aminotransferase (ALT) and aspartate aminotransferase (AST), which are considered criteria to diagnose NAFLD, decreased. Therefore, this result unifies this notion that silymarin can be deemed as a therapeutic agent to be used in NAFLD patients.