Hypothetical link between infertility and genetically modified food

Mingxia Gao, Gao M, Li B, Bin Li, Wenzhen Yuan, Yuan W, Zhao L, Lihui Zhao, Xuehong Zhang, Zhang X
Recent patents on food, nutrition & agriculture · 2014 · doi:10.2174/2212798406666141024111228 · PMID:25342149
other OA: closed public-domain-us
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⚙ AI-generated summary by claude@2026-06, 2026-06-10 ⓘ

This paper speculates that genetically modified foods could potentially cause infertility by affecting endocrine metabolism and endometriosis, but acknowledges limited evidence and need for further research.

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Abstract

It is speculated that genetically modified food (GMF)/genetically modified organism (GMO) is responsible for infertility development. The risk linked with a wide use of GMFs/GMOs offers the basic elements for social criticism. However, to date, it has not been justified whether the bad effects are directly resulted from products of genetic modifications or trans-genesis process. Extensive experience with the risk assessment of whole foods has been applied recently on the safety and nutritional testing of GMFs/GMOs. Investigations have tested the safety of GMFs including sub-acute, chronic, reproductive, multi-generation and carcinogenicity studies. We extrapolated the potential risks associated with GMFs/GMOs on reproduction, and analyzed the multi-aspect linked between infertility and GMFs/GMOs. It could be conjectured that GMFs/GMOs could be potential hazard on reproduction, linking to the development of infertility through influencing the endocrine metabolism, endometriosis. However, little evidence shows the impaction on embryo or reproductive related tumor due to the limited literatures, and needs further research. The article presents some related patents on GMFs/GMOs, and some methods for tracking GMOs.
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Abstract

It is speculated that genetically modified food (GMF)/genetically modified organism (GMO) is responsible for infertility development. The risk linked with a wide use of GMFs/GMOs offers the basic elements for social criticism. However, to date, it has not been justified whether the bad effects are directly resulted from products of genetic modifications or trans-genesis process. Extensive experience with the risk assessment of whole foods has been applied recently on the safety and nutritional testing of GMFs/GMOs. Investigations have tested the safety of GMFs including sub-acute, chronic, reproductive, multi-generation and carcinogenicity studies. We extrapolated the potential risks associated with GMFs/GMOs on reproduction, and analyzed the multi-aspect linked between infertility and GMFs/GMOs. It could be conjectured that GMFs/GMOs could be potential hazard on reproduction, linking to the development of infertility through influencing the endocrine metabolism, endometriosis. However, little evidence shows the impaction on embryo or reproductive related tumor due to the limited literatures, and needs further research. The article presents some related patents on GMFs/GMOs, and some methods for tracking GMOs.

Keywords

Endometriosis, gamete and embryo, genetically modified food, neoplasms, trans-genesis process. 154

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Condition tags

endometriosisinfertility

MeSH descriptors

Fertility Food, Genetically Modified Infertility Organisms, Genetically Modified Patents as Topic Reproduction Animals Diet Endometriosis Endometriosis Female Food, Genetically Modified Humans Infertility Male Neoplasms Neoplasms Plants, Genetically Modified Risk Assessment

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europepmc
last seen: 2026-07-28T06:14:09.330459+00:00
pubmed
last seen: 2026-05-13T22:18:10.358439+00:00
unpaywall
last seen: 2026-06-13T06:42:57.164913+00:00
License: public-domain-us · commercial use OK · attribution required
Courtesy of the U.S. National Library of Medicine