Evaluate the relationship between the incidence of catheter-related bloodstream infection (CRBSI) and phosphorus and parathyroid hormone levels in hemodialysis patients

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Abstract

Objects This study aimed to determine the relationship between phosphorus and PTH levels with the incidence of catheter related blood stream infection (CRBSI) in hemodialysis (HD) patients. Methods: The study was conducted cross-sectionally from April 2021 to September 2022, including individuals who had a permanent catheter for dialysis initiation. Demographic characteristics, physical measurements, and various laboratory tests were recorded, including phosphorus, PTH, and other parameters. The occurrence of CRBSI was also documented. Results: In our study involving hemodialysis patients, out of the 100 participants, 19 individuals experienced catheter-related bloodstream infections CRBSI. The average age of patients with CRBSI (62.62±16.52years) was higher than patients without CRBSI (52.33±16.64years), and this difference was statistically significant ( p-value= 0.02). In individuals with (CRBSI), the mean phosphorus level was5.43± 1.47compared to 4.88±1.08, and the mean PTH level was 406.63±263.97 compared to 306.69±389.15. However, this difference was only found to be statistically significant in the case of PTH (p=0.01) Based on the logistic regression test, it was found that age has a significant relationship with CRBSI. With each year of age, the odds of experiencing a catheter-related blood infection increase by 1.1 times. Conclusion: The study concludes that age is a predictive factor for CRBSI, emphasizing the importance of self-care training in this population. Additionally, individuals with high PTH levels should undergo appropriate measures, such as transitioning from a permanent catheter to arteriovenous fistula (AVF), along with proper self-care training, to reduce infectious complications.

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License: CC-BY-4.0