MicroRNAs in the Mitochondria-Telomere Axis: Novel Insights into Cancer Development and Potential Therapeutic Targets

The intricate molecular interactions between mitochondria and telomeres, establish networks where different RNA species (miRNA or microRNAs) act as a key regulators in the carcinogenesis and tumor progression cascade. Recent evidence has illuminated a sophisticated molecular dialogue between mitochondria and telomeres that regulate cellular metabolism, growth, and apoptosis. This review focuses on the specific functions of diverse RNA species in cancer development and their potential application as biomarkers or therapeutic agents.