Vaginal Natural Orifice Transluminal Endoscopic Surgery (vNOTES) Hysterectomy with Two Previous Renal Transplantations: The First Case in the Literature Two Renal Transplants

Burak Güler, Cem Erdoğan, Ömer Demir, Cihan Comba
Asian journal of endoscopic surgery · 2025 · vol. 18(1) , pp. e70020 · doi:10.1111/ases.70020 · PMID:39854043
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⚙ AI-generated summary by claude@2026-06, 2026-06-13 ⓘ

This case report details the first documented vNOTES hysterectomy performed on a patient with a history of two renal transplants, demonstrating its feasibility for treating adenomyosis and abnormal uterine bleeding.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-13 · read from full text ⓘ

This paper reports the first published case (with a video) of a transvaginal natural orifice transluminal endoscopic surgery (vNOTES) hysterectomy in a 42-year-old woman with a complex history of two prior renal transplants. The patient presented with persistent menorrhagia and hypermenorrhea, refractory to standard treatments, and was diagnosed with adenomyosis and cervical intraepithelial neoplasia grade 3 (CIN3); the authors provide a detailed, step-by-step description of the vNOTES procedure. The main finding is that vNOTES hysterectomy was feasible in this highly complex surgical context, with the paper emphasizing procedural documentation rather than outcomes beyond the case, and implicitly limited by its single-patient design. This paper is centrally about adenomyosis — it describes a vNOTES hysterectomy performed for refractory uterine bleeding due to adenomyosis in a patient with prior renal transplants.

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Abstract

This study demonstrates the feasibility of performing a Transvaginal Natural Orifice Transluminal Endoscopic Surgery (vNOTES) hysterectomy on a patient with a complex surgical history, including two renal transplants. The case involves a 42-year-old female presenting with persistent menorrhagia and hypermenorrhea, unresponsive to standard treatments, and diagnosed with adenomyosis and CIN3. A detailed, step-by-step procedure of the vNOTES technique is provided, marking the first video article to document vNOTES hysterectomy in such a medical context. The findings highlight vNOTES as a viable approach for treating refractory uterine bleeding and adenomyosis in patients with prior transplants, offering insights for young surgeons considering this minimally invasive technique in complex cases.
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Vaginal Natural Orifice Transluminal Endoscopic Surgery (vNOTES) Hysterectomy with Two Previous Renal Transplantations: The First Case in the Literature Two Renal Transplants ABSTRACT This study demonstrates the feasibility of performing a Transvaginal Natural Orifice Transluminal Endoscopic Surgery (vNOTES) hysterectomy on a patient with a complex surgical history, including two renal transplants. The case involves a 42-year-old female presenting with persistent menorrhagia and hypermenorrhea, unresponsive to standard treatments, and diagnosed with adenomyosis and CIN3. A detailed, step-by-step procedure of the vNOTES technique is provided, marking the first video article to document vNOTES hysterectomy in such a medical context. The findings highlight vNOTES as a viable approach for treating refractory uterine bleeding and adenomyosis in patients with prior transplants, offering insights for young surgeons considering this minimally invasive technique in complex cases. Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request.

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Condition tags

adenomyosis

MeSH descriptors

Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis

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