Validation of Risk Models for Contrast-Induced Nephropathy following Percutaneous Coronary Intervention in Chinese Population

Validation of Risk Models for Contrast-Induced Nephropathy following Percutaneous Coronary Intervention in Chinese Population | Authorea try { document.documentElement.classList.add('js'); } catch (e) { } var _gaq = _gaq || []; _gaq.push(['_setAccount', 'G-8VDV14Y67G']); _gaq.push(['_trackPageview']); (function() { var ga = document.createElement('script'); ga.type = 'text/javascript'; ga.async = true; ga.src = ('https:' == document.location.protocol ? 'https://ssl' : 'http://www') + '.google-analytics.com/ga.js'; var s = document.getElementsByTagName('script')[0]; s.parentNode.insertBefore(ga, s); })(); Skip to main content Preprints Collections Wiley Open Research IET Open Research Ecological Society of Japan All Collections About About Authorea FAQs Contact Us Quick Search anywhere Search for preprint articles, keywords, etc. Search Search ADVANCED SEARCH SCROLL This is a preprint and has not been peer reviewed. Data may be preliminary. 26 June 2025 V1 Latest version Share on Validation of Risk Models for Contrast-Induced Nephropathy following Percutaneous Coronary Intervention in Chinese Population Authors : Dunsong Fan 0000-0001-6869-1758 [email protected] , Minhua Lin , and Yujia Wang Authors Info & Affiliations https://doi.org/10.22541/au.175092856.64557604/v1 139 views 88 downloads Contents Abstract Supplementary Material Information & Authors Metrics & Citations View Options References Figures Tables Media Share Abstract Background： Contrast-induced nephropathy is a common complication after cardiac interventional procedures. Methods: Our study assessed the application of risk score of Mehran, National Cardiovascular Data Registry-Acute Kidney Injury (NCDR) and 3-variable (AGEF score) based on age, left ventricular ejection fraction, and estimated glomerular filtration rate for contrast-induced nephropathy following Percutaneous Coronary Intervention in Chinese population. Discrimination of risk models was evaluated via the area under the receiver operating curve (AUC), while calibration of risk models was assessed by the goodness of fit test. Results: Discrimination of 3 risk models improved a lot with the definition of contrast-induced nephropathy that was recommend by Kidney Disease: Improving Global Outcome (KDIGO) than with the definition of contrast-induced nephropathy that was recommend by Contrast Media Safety Committee, European Society of Urogenital Radiology (ESUR CMSC). Mehran model and AGEF model exhibited good calibration. However, NCDR model obtained Hosmer-Lemeshow p value of 0.024 (contrast-induced nephropathy defined by ESUR CMSC) and Hosmer-Lemeshow p value of 0.118 (contrast-induced nephropathy defined by KDIGO). Conclusion: Mehran model, AGEF model and NCDR model showed favourable performance in contemporary Chinese interventional cardiology when the contrast-induced nephropathy definition was recommend by KDIGO. Supplementary Material File (validation of risk models for contrast-induced nephropathy following percutaneous coronary intervention in chinese population.20250618doc.doc.doc) Download 13.36 MB Information & Authors Information Version history V1 Version 1 26 June 2025 Copyright This work is licensed under a Non Exclusive No Reuse License. Keywords agef contrast-induced nephropathy mehran ncdr risk score Authors Affiliations Dunsong Fan 0000-0001-6869-1758 [email protected] Longyan First Hospital View all articles by this author Minhua Lin Ningde Municipal Hospital of Ningde Normal University View all articles by this author Yujia Wang Ningde Municipal Hospital of Ningde Normal University View all articles by this author Metrics & Citations Metrics Article Usage 139 views 88 downloads .FvxKWukQNSOunydq8rnd { width: 100px; } Citations Download citation Dunsong Fan, Minhua Lin, Yujia Wang. Validation of Risk Models for Contrast-Induced Nephropathy following Percutaneous Coronary Intervention in Chinese Population. Authorea . 26 June 2025. DOI: https://doi.org/10.22541/au.175092856.64557604/v1 If you have the appropriate software installed, you can download article citation data to the citation manager of your choice. Simply select your manager software from the list below and click Download. For more information or tips please see 'Downloading to a citation manager' in the Help menu . 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