The correlation between estradiol, 25 hidroxyvitamin D and quality of life among postmenopausal women

Retno Hartanti, Satiyem Satiyem, I Wayan Arsana Wıyasa, Nurdiana Nurdiana, Umi Kalsum, Maya Devi Arifiandi, Bagus Putu Putra Suryana
In: AIP Conference Proceedings · 2021 · vol. 2353 , pp. 030100 · doi:10.1063/5.0052864 · W3165545737
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This study found significant correlations between lower estradiol and 25(OH)D levels and decreased quality of life in postmenopausal women.

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Abstract

Estradiol decreases in postmenopausal women cause several changes in the physical, physiological, and psychological aspects. Consequently, various complaints emerged and affected women's quality of life (QoL). Vitamin D [25(OH)D] is an alternative to relieve menopausal complaints. This study aimed to examine the relationship between estradiol, 25(OH)D, and the QoL among postmenopausal women. This study applied a descriptive-analytic and consecutive sampling technique. The inclusion criteria were postmenopausal and physiological menopause women who were willing to participate in this study. The exclusion criteria were postmenopausal women with severe illness and under steroid treatments. ELISA, ECLIA, and MENQOL were used to examine 25(OH)D, estradiol, and QoL, respectively. The data were analyzed using SPSS version 23.0. The results showed thirty-nine postmenopausal women participated in this study. The average estradiol level was 5.68 pg/mL (SD ± 2.20), ranged from 5 to 16.07 pg/mL. There was a significant correlation between estradiol levels and QoL (r = −0.349; p = 0.029), and 25(OH)D and QoL (r = −0.383; p = 0.016). In conclusion, estradiol and 25(OH)D have a notable role in postmenopausal complaints. The QoL is a maJor consideration in postmenopausal women's life.

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