The effects of spontaneous luteinizing hormone surges on superovulatory cycles

James W. Akin; Akin JW; J W Akin; Shepard MK; Marguerite K. Shepard; M K Shepard; Sandefur HJ; Jana Sandefur; H J Sandefur; Kim K. Cox; K K Cox; Cox KK

doi:10.1016/s0015-0282(16)55321-7

The effects of spontaneous luteinizing hormone surges on superovulatory cycles

James W. Akin, Akin JW, J W Akin, Shepard MK, Marguerite K. Shepard, M K Shepard, Sandefur HJ, Jana Sandefur, H J Sandefur, Kim K. Cox, K K Cox, Cox KK

Fertility and sterility · 1992 · vol. 58(4) , pp. 740–743 · doi:10.1016/s0015-0282(16)55321-7 · PMID:1426319 · W2417795803

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This retrospective study of 1,185 superovulatory cycles found that the spontaneous occurrence of an LH surge did not impact cycle fecundity or pregnancy rates, regardless of infertility diagnosis.

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Abstract

ObjectiveTo determine the effect of a spontaneous luteinizing hormone (LH) surge on the cycle fecundity during superovulation induction.DesignSuperovulatory cycles of patients with various diagnoses are retrospectively compared.SettingReproductive Endocrinology Outpatient Clinic.PatientsA total of 1,185 superovulatory cycles from July 1, 1982 until November 1, 1991 are compared.Main outcome measureThe probability of achieving a pregnancy per treatment cycle.ResultsPatients with unexplained infertility and hyperprolactinemia were more likely to have a spontaneous LH surge during superovulation than patients with either endometriosis or polycystic ovarian disease. However, the cycle fecundity rate did not differ whether or not an LH surge occurred, regardless of the diagnosis.ConclusionsSpontaneous onset of an LH surge during superovulation induction does not influence the chances for pregnancy.

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MeSH descriptors

Luteinizing Hormone Superovulation Adult Female Humans Infertility, Female Infertility, Female Infertility, Female Luteinizing Hormone Luteinizing Hormone Menotropins Menotropins Retrospective Studies

Citation neighborhood (sparse)

Too few in-corpus citations on either side for a chart; here are the lists.

Cites (1)

Luteal function in patients with endometriosis. 1989

References (15)

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[1] Luteal function in patients with endometriosis. 1989