Representative Survey on the Public Opinion and Attitudes Toward Uterus Transplantation in Hungary

Background: /Objectives: Uterus transplantation (UTx) is a novel, clinically successful treatment option for patients with absolute uterine factor infertility (AUFI) seeking biolog-ical motherhood. The procedure has been performed over 100 times worldwide in the past decade at 20 centers, but it remains widely unfamiliar, even among healthcare profes-sionals. This study assessed general knowledge of the procedure and identified knowledge gaps to better understand the general population’s perception of UTx in prep-aration for Hungary’s first procedure. Methods: This prospective study, conducted between December 18, 2024, and January 5, 2025, distributed an online survey to 1500 Hungarian men and women aged 18 to 70 via e-mail. The questionnaire contained 24 questions on their opinions about organ donation, transplantation, infertility, surrogacy, and uterus transplantation. Results: Most of the participants (77%, 1155/1500) supported UTx (strongly agree: 44%, 660/1500; agree: 33%, 495/1500). Among participants personally affected by fertility prob-lems, 84% (152/181) supported UTx, with 51% (92/181) strongly agreeing that it should be performed. Only 4% of respondents rejected UTx. Notably, only 15% of respondents had heard of UTx being performed abroad. Conclusions: Our representative online survey demonstrates favorable public attitudes and opinions regarding UTx; increased public awareness is necessary for higher ac-ceptance rates.