Integrative whole-exome and transcriptome analyses reveal an invasion-like “motility–adhesion–cytoskeleton” program in endometriosis and validate its PI3K/AKT dependency in vitro

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Abstract

Integrative WES–RNA‑seq profiling highlights a coordinated invasion‑like program in endometriosis with functional dependence on PI3K/AKT signaling, supporting PI3K/AKT as a mechanistically grounded target for anti‑invasive strategies in endometriosis.

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last seen: 2026-06-21T06:06:47.764508+00:00
License: CC0 · commercial use OK