A needle in a haystack: Navigating equine injectable drug reactions

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Abstract

The case report by Vandecandelaere et al. (2025) describing two fatalities following administration of extended-release injectable omeprazole (ERIO) provides an important opportunity to reflect on the inherent risks associated with parenteral drug administration in horses. While these deaths are undoubtedly tragic, it is essential to contextualise this risk within the broader landscape of equine injectable therapeutics to provide balanced clinical guidance.
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A needle in a haystack: Navigating equine injectable drug reactions | Authorea try { document.documentElement.classList.add('js'); } catch (e) { } var _gaq = _gaq || []; _gaq.push(['_setAccount', 'G-8VDV14Y67G']); _gaq.push(['_trackPageview']); (function() { var ga = document.createElement('script'); ga.type = 'text/javascript'; ga.async = true; ga.src = ('https:' == document.location.protocol ? 'https://ssl' : 'http://www') + '.google-analytics.com/ga.js'; var s = document.getElementsByTagName('script')[0]; s.parentNode.insertBefore(ga, s); })(); Skip to main content Preprints Collections Wiley Open Research IET Open Research Ecological Society of Japan All Collections About About Authorea FAQs Contact Us Quick Search anywhere Search for preprint articles, keywords, etc. Search Search ADVANCED SEARCH SCROLL Equine Veterinary Education This is a preprint and has not been peer reviewed. Data may be preliminary. 31 January 2026 V1 Latest version Share on A needle in a haystack: Navigating equine injectable drug reactions Author : Gayle Hallowell 0000-0003-2294-6502 [email protected] Authors Info & Affiliations https://doi.org/10.22541/au.176989154.42590811/v1 Published Equine Veterinary Education Version of record Peer review timeline 136 views 62 downloads Contents Abstract Supplementary Material Information & Authors Metrics & Citations View Options References Figures Tables Media Share Abstract The case report by Vandecandelaere et al. (2025) describing two fatalities following administration of extended-release injectable omeprazole (ERIO) provides an important opportunity to reflect on the inherent risks associated with parenteral drug administration in horses. While these deaths are undoubtedly tragic, it is essential to contextualise this risk within the broader landscape of equine injectable therapeutics to provide balanced clinical guidance. Supplementary Material File (a_needle_in_a_haystack_formatted.docx) Download 26.30 KB Information & Authors Information Version history V1 Version 1 31 January 2026 Peer review timeline Published Equine Veterinary Education Version of Record 1 Mar 2026 Published Copyright This work is licensed under a Non Exclusive No Reuse License. Collection Equine Veterinary Education Authors Affiliations Gayle Hallowell 0000-0003-2294-6502 [email protected] Medicine Vet Equine Referrals View all articles by this author Metrics & Citations Metrics Article Usage 136 views 62 downloads .FvxKWukQNSOunydq8rnd { width: 100px; } Citations Download citation Gayle Hallowell. A needle in a haystack: Navigating equine injectable drug reactions. Authorea . 31 January 2026. DOI: https://doi.org/10.22541/au.176989154.42590811/v1 If you have the appropriate software installed, you can download article citation data to the citation manager of your choice. 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