Modern antioestrogens and the coming revolution in women's health care

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AI-generated summary by claude@2026-06, 2026-06-11

This review discusses traditional and modern antioestrogens and SERMs, their effects on breast, uterus, bone, and lipids, and their future use in gynaecological conditions and breast cancer.

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Abstract

This review will focus on antioestrogens and selective oestrogen receptor modulators (SERMS). The more traditional SERMS, clomiphene citrate and tamoxifen, will be reviewed along with such modern drugs as raloxifene and faslodex, with emphasis upon their actions on breast, uterus, bone and lipids. The future potential of these medications, in the management of oestrogen-dependent gynaecological conditions such as endometriosis, dysfunctional uterine bleeding, fibroids and breast cancer will be discussed.

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Condition tags

endometriosis

MeSH descriptors

Estrogen Receptor Modulators Estrogen Receptor Modulators Estrogen Receptor Modulators Genital Diseases, Female Isoflavones Selective Estrogen Receptor Modulators Selective Estrogen Receptor Modulators Selective Estrogen Receptor Modulators Bone and Bones Bone and Bones Breast Neoplasms Breast Neoplasms Clomiphene Clomiphene Clomiphene Estradiol Estradiol Estradiol Estradiol Estrogens, Non-Steroidal

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Source provenance

europepmc
last seen: 2026-08-08T06:08:32.324769+00:00
pubmed
last seen: 2026-05-13T22:10:24.024533+00:00
unpaywall
last seen: 2026-06-13T06:42:57.164913+00:00
License: public-domain-us · commercial use OK · attribution required
Courtesy of the U.S. National Library of Medicine