Vocal effects of danazol therapy. A preliminary report
Non-randomised trial
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⤵ 3 in-corpus citations
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This preliminary study examined 23 women undergoing danazol therapy and found no significant vocal changes attributable to the drug's androgenic properties, with only minor frequency shifts observed in a few patients.
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Abstract
Vocal effects of danazol therapy were studied in 23 women. Before danazol therapy was started the patients were examined by a phonitrician using indirect laryngoscopy and microlaryngoscopy in stroboscopic light. A glottographic frequency indication ad modum Kitzing and a tape-recording were also made. These examinations were carried out again after 3 and 6 months of therapy. The patients mostly received 600 mg danazol daily. One of the patients noticed a very marked change in her voice after 2 weeks of therapy. This patient also had conjunctivitis and the reaction was judged to be an allergic reaction to the drug and not a hormonal side effect. In 4 of the other 22 patients the glottographic frequency indication showed a slight decrease in the mean frequency and in 3 a slight increase within the normal range of interpersonal variation. None of the patients noticed subjectively any virilization of the voice. In this preliminary study we have not found any significant vocal changes in the 23 patients tested that could be attributed to the androgenic properties of danazol.
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Too few in-corpus citations on either side for a chart; here are the lists.
Cites (2)
- Danazol in the treatment of endometriosis 1980
- The use of danazol in the management of endometriosis. 1977
Cited by (3)
References (2)
- Danazol in the treatment of endometriosis via openalex
- The use of danazol in the management of endometriosis. via openalex
Cited by (3)
Source provenance
- openalex
- last seen: 2026-05-10T11:09:28.365004+00:00
- pubmed
- last seen: 2026-10-08T21:58:20.576574+00:00
- unpaywall
- last seen: 2026-10-17T06:24:38.187582+00:00
License: CC0
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