Роль препаратів кальцію та вітаміну D у профілактиці постменопаузального розвитку остеопорозу у пацієнток із ендометріозом

Role of calcium and vitamin d in prevention of postmenopausal osteoporosis in patients with endometriosis DOI: https://doi.org/10.18370/2309-4117.2015.22.70-75Keywords: endometriosis, menopause, osteoporosis, vitamin D, Calcium-D3 NycomedAbstract The study to assess the effectiveness of the use of the drug Calcium-D3 Nycomed for the prevention and correction of disorders of calcium-phosphorus metabolism, bone metabolism in 67 patients with endometriosis on the background of climacteric syndrome and calcium deficiency was performed. 35 patients (main group) against the symptomatic treatment of climacteric syndrome were prescribed Calcium-D3 Nycomed. 32 patients, who did not receive calcium supplements, entered the control group. The period of observation in the course of treatment was 3 months. The most important result of the treatment was slowing or stopping bone loss resulting from the use of Calcium-Dз Nycomed. It is possible to recommend the use of this drug in patients with endometriosis and symptoms of hypocalcemia on the background of climacteric syndrome for the prevention and treatment of osteopenic syndrome References - Adamyan, L.V. Genetic aspects of gynecological diseases. Moscow. GEOTAR -Media (2008): 164–168. - Baran, D.T., Faulkner, K.G., Genant, H.K., Miller, P.D. “Diagnostics and treatment of osteoporosis: the principles of the bone densitometry use.” Osteoporosis and osteopathy, 3(1998): 10–15. - Zakharenko, N.F., Tatarchuk, T.F., Kovalenko, N.V. “The role of oxidative stress in the genesis of endometriosis.” Reproductive Endocrinology, 4(18) (2014): 13–16. - Medical and demographic atlas of Ukraine. Ukraine in the European context, the main causes of mortality. Issue 14 / V.P. Voitenko, A.V. Pisaruk, N.M. Koshel, M.G. Akhaladze. Kyiv. Fenix (2012): 62 p. - Smetnik, V.P., Yureneva, S.V. “Postmenopausal osteoporosis.” Difficult Patient, 6 (Vol. 2) (2004): 27–33. - Toroptseva, N.V. “Prevention of postmenopausal osteoporosis: the role of calcium and vitamin D.” Gynecology, 5–6 (Vol. 7) (2006): 52–55. - Body, J.J., et al. “Vitamin D with calcium reduces mortality: patient level pooled analysis of 70.528 patient fromeight major vitamin D trials.” Osteoporos Int, 23(Suppl. 1) (2012): 1–23. - R ejnmark, L., Aveneil, A., Masud, T., et al. “Vitamin D with Calcium Reduces Mortality: Patient Level Pooled Analysis of 70,528 Patients from Eight Major Vitamin D Trials.” J Clin Endocrin Metab, (2012): 1–12. - Buyalos, R.P., et al. “Endometriosis-associated infertility.” Curr Opin Obstet Gynecol, 12(2000): 377–381. - C urhan, G.C., Willett, W.C., et al. “Dietary factors and the risk of incident kidney stones in younger women: Nurses’ Health Study ІІ.” Arch Intern Med, 164(8) (2004): 885–891. - Hummelshoj, L. “Medical needs in endometriosis.” Gynaecology Forum, 15(2) (2010): 5–7. - N eukomm, C., et al. “Die Endometriose – eine wenig bekannte, oft unerkannte Frauenkrankheit.” Schweiz Med Forum, 8(30–31) (2008): 539–543. - C occia, M.E., et al. Hum Reprod, 11(2011): 3000–3007. Downloads Published How to Cite Issue Section License Copyright (c) 2015 Н. Ф. Захаренко, Н. В. Коваленко, В. П. Ковбасий This work is licensed under a Creative Commons Attribution 4.0 International License. Authors who publish with this journal agree to the following terms: - Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal. - Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.