Update on the diagnosis and treatment of bladder endometriosis

review OA: closed public-domain-us
Full text JSON View on PubMed View at publisher
AI-generated summary by claude@2026-06, 2026-06-13

Bladder endometriosis, characterized by cyclical pain and menouria, is best diagnosed with cystoscopy and histology, and treatment is individualized based on patient factors using hormonal or surgical approaches.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

AI-generated deep summary by claude@2026-06, 2026-06-13 · read from full text

This paper reviews bladder endometriosis, focusing on its rarity, typical symptoms (including cyclic menouria and urethral/pelvic pain), and the diagnostic and treatment approach. It emphasizes that imaging is not definitive, while cystoscopy is described as the most useful diagnostic test, with histologic confirmation, and that management should be individualized based on age, future pregnancy desires, symptom severity, lesion site, and whether other organs are involved. The main treatment categories covered are medical-hormonal therapy and surgical treatment, but the paper’s caveat is that imaging is not conclusive for diagnosis, which can complicate preoperative certainty. This paper is centrally about endometriosis — it is specifically an update on the diagnosis and treatment of bladder endometriosis.

Read from the paper's body, not the abstract. Not a substitute for reading the paper. No clinical advice. How this works

Abstract

Bladder endometriosis is rare, although the bladder is the urinary tract structure most often affected by this condition. The common clinical manifestations of bladder endometriosis include menouria and urethral and pelvic pain syndrome occurring cyclically. Imaging methods are not conclusive for the definitive diagnosis. Cystoscopy is the most useful diagnostic test with confirmation by histologic study. Treatment must be individualized according to the patient's age, desire for future pregnancies, the severity of the symptoms, the site affected, and whether other organs are involved. Two types of treatment are currently used as follows: medical-hormonal and surgical.
Full text 7,370 characters · extracted from oa-doi-fallback · 2 sections · click to expand

Abstract

Bladder endometriosis is rare, although the bladder is the urinary tract structure most often affected by this condition. The common clinical manifestations of bladder endometriosis include menouria and urethral and pelvic pain syndrome occurring cyclically. Imaging methods are not conclusive for the definitive diagnosis. Cystoscopy is the most useful diagnostic test with confirmation by histologic study. Treatment must be individualized according to the patient’s age, desire for future pregnancies, the severity of the symptoms, the site affected, and whether other organs are involved. Two types of treatment are currently used as follows: medical-hormonal and surgical. Similar content being viewed by others

References

Llarena Ibarguren R, Lecumberri Castaños D, Padilla Nieva J, Crespo Atin V, Martin Bazaco J, Azurmendi Sastre V, Pertusa Peña C (2002) Endometriosis urinaria. Arch Esp Urol 55:209–215 Bologna RA, Whitmore KE (2001) La endometriosis genitourinaria. In: Ball TP (ed) AUA update series, vol 1 (Spanish ed). Medical Trends, Barcelona, pp 21–29 Vorstman B, Lynne C, Politano VA (1983) Postmenopausal vesical endometriosis. Urology 22:540–542 Westney OL, Amundsen CL, McGuire EJ (2000) Bladder endometriosis: conservative management. J Urol 163:1814–1817 Comiter CV (2002) Endometriosis de la via urinaria. Urologia femenina. Clin Urol North Am 3:635–645 (Spanish edition) Shook TE, Nyberg LM (1988) Endometriosis of the urinary tract. Urology 31:1–6 Ong CL, Tung KH (1991) Bladder endometriosis: three case reports and a review. Aust NZ J Surg 61:81–83 Stanley KE, Utz DC, Dockerty MB (1965) Clinical significant endometriosis of the urinary tract. Surg Gynecol Obstet 120:491–498 Leiva O, Ortiz Vico F (1998) Endocervicosis de la vía urinaria: sistema mülleriano secundario. In: Patologías excepcionales en Urología. Ed. Luzán, Madrid, pp 11–43 Clement PB, Young RH (1992) Endocervicosis of the urinary bladder. A report of six cases of benign mullerian lesion that may mimic adenocarcinoma. Am J Surg Pathol 16:533–542 Spencer SL, Rubin MA, Hussain H, Wolf JS Jr (2001) Complete transurethral resection of bladder endocervicosis. J Urol 165:524 Rodriguez R, Alfert H (1997) Endocervicosis of the bladder: a rare mucinous analogue of endometriosis. J Urol 157:1355 Von Recklinghausen F (1986) Die Adenomyome und Cist Adenomyome der Uterus un Tuben Wandung, ihre abkunft von resten des Wolffschen Koerpers. A. Airschwald, Berlin, p 247 Cullen TJ (1917) Adenomyoma of the rectovaginal septum. Bull Johns Hopkins Hosp 28:343–349 Kossman R (1987) Die abstammung des drusenein-schlusse in den adenomyomen des uterus un der tuben. Arch f Gynak 54:359–383 Petriconi R, Hautmann R (1987) Problèmes diagnostics et thérapeutiques des endométriosis de la vessie. J Urol (Paris) 93:205–207 Cifuentes Delatte L (1947) Endometriosis vesical. In: Cifuentes L (ed) Cistitis y cistopatías, 1st edn. Paz Montalvo, Madrid, Spain, pp 375–380 Iwanoff N (1898) Drusiges cystenhaltiges uterus fibroyom compliziert durch sarkom und karzinom. Monatschr.f.Geburtsch. u Gynak 7:295 Meyer R (1924) Die Bedeutung der heterotopen Epithelwuchnerung im Ovarium und am Peritoneum. Zentralb f Gynak 14:722–725 Dreyfus ML (1940) Internal endometriosis of the urinary bladder. Am J Obst Gyn 39:336–340 Krestchmer HI (1945) Endometriosis of the bladder. J Urol 53:459–465 Silmi Moyano A, Blázquez Izquierdo J, Salinas Casado J, Gomez Vegas A, Corral Rosillo J, Lopez JA, Asenjo G, Gomez Ruiz J, Uson Calvo A (1990) Endometriosis vesical. Revisión y presentación de dos casos. Rev Clin Esp 186:74–81 Sampson JA (1927) Peritoneal endometriosis due to menstrual dissemination of endometrial tissue into the peritoneal cavity. Am J Obstet Gynecol 14:422–469 Jacobson VC (1922) Autotransplantation of endometrial tissue in the rabbit. Arch Surg 5:281–300 Vercellini P, Frontino G, Pietropaolo G, Gattei U, Daguati R, Crosignani PG (2004) Deep endometriosis: definition, pathogenesis, and clinical management. J Am Assoc Gynecol Laparosc 11:153–161 Javert CI (1949) Pathogenesis of endometriosis based on endometrial horneoplasia, direct extensíon, exfoliation and implantation, lymphatic and hematogenus metastasis (including 5 cases reports of endometrial tissue in pelvic lymph nodes). Cancer 2:399 Abeshouse BS, Abeshouse G (1960) Endometriosis of the urinary tract. J Int Coll Surg 34:43–63 Henriksen E (1935) Primary endometriosis of the urinary bladder. JAMA 104:1401 Judd ES (1921) Adenomyoma presenting as a tumor of the bladder. Surg Clin North Am 1:1271–1273 Gooddall JR (1943) A study of endometriosis, endosalpyngosis, endocervicosis and peritoneo-ovarian sclerosis. Lippincott, Philadelphia, p 89 Sampson JA (1928) Endometriosis following salpingectomy. Am J Obstet Gynecol 16:461–499 Chapron C (2003) Doleur et endometriose profonde. J Gynecol Obstet Biol Reprod 32:32–36 Tarragona Forada J, De Torres Ramirez I, Morote Robles J, Lopez Palacios JL, De Torres Mateos JA (1997) Vesical endometriosis. Report of a case with immunohistochemical study. Arch Esp Urol 50:74–76 Donne C, Vidal M, Buttin X, Becerra P, Carvia R, Zuluaga A, Nogales FF (1998) Mullerianosis of the urinary bladder: clinical and immunohistochemical findings. Histopathology 33:290–292 Muller J (1927) Endometrioide adenomatose (denomyosis) und cystadenomatose der harnblase. Arch F KlinChir 145:394–434 Ottaw B (1929) Dasklinische blid der endometriose der harnblase. Arch Gynak 3:137–138 Mostoufizadeh M, Scully RE (1980) Malignant tumors arising in endometriosis. Clin Obstet Ginecol 3:973–985 Lopez JA, Peres-Arbés JA, Escivá PLÁJ, Romero Aguirre F (1986) Adenocarcinoma escamoso de vejiga con componente endometriode, comentarios sobre un caso. Act Urol Esp 10:217–220 Vara AR, Ruzics EP, Moussabeck O, Martin DC (1990) Endometrioid adenosarcoma of the bladder arising from endometriosis. J Urol 143:813–815 Balat O, Kudelka AP, Edwards CL, Silva E, Kavanagh JJ (1996) Malignant transformation in endometriosis of the urinary bladder: case report of clear cell adenocarcinoma. Eur J Gynaecol Oncol 17:13–16 Garavan F, Grainger R, Jeffers M (2004) Endometrioid carcinoma of the urinary bladder complicating vesical Mullerianosis: a case report and review of the literature. Virchows Arch 444:587–589 Price DT, Maloney KE, Ibrahim GK, Cundiff GW, Leder RA, Anderson EE (1996) Vesical endometriosis: report of two cases and review of the literature. Urology 48:639–643 Sanchez Merino JM, Guillan Maquieira C, Garcia Alonso J (2005) Tratamiento de la endometriosis vesical. Revisión de la literatura española. Arch Esp Urol 58:189–194 Martin A, Plasencia W, Garcia R, Medina N, Garcia JA (2003) Tratamiento laparoscópico de la endometriosis vesical. Prog Obstet Ginecol 46:403 Fedele L, Bianchi S, Zanconato G, Portuese A, Raffaelli R (2001) Use of a levonorgestrel-releasing intrauterine device in the treatment of rectovaginal endometriosis. Fertil Steril 75:485–488 Author information Authors and Affiliations Corresponding author Rights and permissions About this article Cite this article Pastor-Navarro, H., Giménez-Bachs, J.M., Donate-Moreno, M.J. et al. Update on the diagnosis and treatment of bladder endometriosis. Int Urogynecol J 18, 949–954 (2007). https://doi.org/10.1007/s00192-007-0342-8 Received: Accepted: Published: Issue date: DOI: https://doi.org/10.1007/s00192-007-0342-8

Text is read by the "Ask this paper" AI Q&A widget below. Extraction quality varies by source — PMC NXML preserves structure cleanly, OA-HTML may include some navigation residue, and OA-PDF can have broken hyphenation. The publisher copy (via DOI) is the canonical version.

My notes (saved in your browser only)

Ask this paper AI returns verbatim quotes from the full text · source: oa-doi-fallback

Answers must be backed by verbatim quotes from this paper's full text. Hallucinated quotes are dropped automatically; if no verbatim passage answers the question, we say so. How this works

Condition tags

endometriosisbladder_endometriosis

MeSH descriptors

Endometriosis Endometriosis Urinary Bladder Diseases Urinary Bladder Diseases Endometriosis Endometriosis Female Humans Urinary Bladder Diseases Urinary Bladder Diseases

Citation neighborhood (no data yet)

We don't have any in-corpus citations linked to this paper yet. The paper's references may be in our DB but unresolved to ``paper_id`` (resolution happens at ingest when the cited DOI matches a row we already have). Run the cross-source citation reconcile pass to retry.

Source provenance

europepmc
last seen: 2026-06-21T06:12:49.409960+00:00
pubmed
last seen: 2026-05-13T22:15:00.519696+00:00
unpaywall
last seen: 2026-06-13T06:42:57.164913+00:00
License: public-domain-us · commercial use OK · attribution required
Courtesy of the U.S. National Library of Medicine