UV Based Advanced Oxidation Process for Degradation of Ciprofloxacin: Reaction Kinetics, Effects of Interfering Substances and Degradation Product Identification

UV Based Advanced Oxidation Process for Degradation of Ciprofloxacin: Reaction Kinetics, Effects of Interfering Substances and Degradation Product Identification | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Research Article UV Based Advanced Oxidation Process for Degradation of Ciprofloxacin: Reaction Kinetics, Effects of Interfering Substances and Degradation Product Identification Bijoli Mondal, Shib Sankar Basak, Arnab Das, Sananda Sarkar, Asok Adak This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-872896/v1 This work is licensed under a CC BY 4.0 License Status: Posted Version 1 posted You are reading this latest preprint version Abstract In the photochemical UV-H 2 O 2 advanced oxidation process, H 2 O 2 absorbs UV light and is decomposed to form hydroxyl radicals (OH · ), which are highly excited and reactive for electron-rich organic compounds and hence can degrade organic compounds. In the present work, the UV-H 2 O 2 process was investigated to degrade ciprofloxacin (CIP), one of India's widely used antibiotics, from aqueous solutions using a batch type UV reactor having photon flux = 1.9 (± 0.1) ×10 -4 Einstein L -1 min -1 . The effects of UV irradiation time on CIP degradation were investigated for both UV and UV-H 2 O 2 processes. It was found that about 75% degradation of CIP was achieved within 60 s with initial CIP concentration and peroxide concentration of 10 mg L -1 and 1 mol H 2 O 2 / mol CIP, respectively, at pH of 7(±0.1) and fluence dose of 113 mJ cm -2 . The experimental data were analyzed by the first-order kinetics model to find out the time- and fluence-based degradation rate constants. Under optimized experimental conditions (initial CIP concentration, pH and H 2 O 2 dose of 10 mg L -1 , 7(±0.1) and 1.0 mol H 2 O 2 / mol CIP, respectively), the fluence-based pseudo-first-order rate constant for the UV and UV-H 2 O 2 processes were determined to be 1.28(±0.0) ×10 -4 and 1.20(±0.04) ×10 -2 cm 2 mJ -1 respectively. The quantum yields at various pH under direct UV were calculated. The impacts of different process parameters such as H 2 O 2 concentration, solution pH, initial CIP concentration, and wastewater matrix on CIP degradation were also investigated in detail. CIP degradation was favorable in acidic conditions. Six degradation products of CIP were identified. Results clearly showed the potentiality of the UV-H 2 O 2 process for the degradation of antibiotics in wastewater. Environmental Policy Antibiotics Ciprofloxacin Degradation Direct Photolysis Scavenging effect UV-H2O2 Full Text Cite Share Download PDF Status: Posted Version 1 posted You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. Our growing team is made up of researchers and industry professionals working together to solve the most critical problems facing scientific publishing. Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-872896","acceptedTermsAndConditions":true,"allowDirectSubmit":true,"archivedVersions":[],"articleType":"Research Article","associatedPublications":[],"authors":[{"id":67938446,"identity":"01c123f5-4561-46ca-925b-07aa3ffeba36","order_by":0,"name":"Bijoli Mondal","email":"","orcid":"","institution":"Haldia Institute of Technology","correspondingAuthor":false,"prefix":"","firstName":"Bijoli","middleName":"","lastName":"Mondal","suffix":""},{"id":67938447,"identity":"8b8a8bee-cdd7-44c6-a4cb-492eac1ed56f","order_by":1,"name":"Shib Sankar Basak","email":"","orcid":"","institution":"Indian Institute of Engineering Science and 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Adak","email":"data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAZAAAAAyAQMAAABI0h/eAAAABlBMVEX///8AAABVwtN+AAAACXBIWXMAAA7EAAAOxAGVKw4bAAAA8ElEQVRIie2RvarCQBBGZ1mIzYLt2LivEFkQBR8mIWClcOE2FhIWBNOItj6GvsHCQCrB1sJCG+vcRiwuYn5AbDZaWuxpdlg4fPMxAA7Hd8IhAwSvAWCC56dfr7B1ofBKwY8ULqqwEny7VXNFpAbTXrjkwMxpEsdS83MGP0ergodhFI1SDOflYjtC33gKwb/YYw5C0VijKruEc4N5i27ehayG3O8U9Z/KPUapG9daxTcjFTGN7UrRHMGI+pRO3qWzSAuFaROk1NqQ+MWgRmnvifA2jYVMZvSXD02ZJNss+7crLzBdvcWBgk8Eh8PhcFh5AAa5SYneeSMFAAAAAElFTkSuQmCC","orcid":"https://orcid.org/0000-0001-9113-6728","institution":"Indian Institute of Engineering Science and Technology, Shibpur","correspondingAuthor":true,"prefix":"","firstName":"Asok","middleName":"","lastName":"Adak","suffix":""}],"badges":[],"createdAt":"2021-09-03 18:05:39","currentVersionCode":1,"declarations":"","doi":"10.21203/rs.3.rs-872896/v1","doiUrl":"https://doi.org/10.21203/rs.3.rs-872896/v1","draftVersion":[],"editorialEvents":[],"editorialNote":"","failedWorkflow":false,"files":[{"id":16220802,"identity":"26a1e9fb-b92a-4cbc-9886-70c354a61ef1","added_by":"auto","created_at":"2021-12-06 17:44:01","extension":"pdf","order_by":1,"title":"","display":"","copyAsset":false,"role":"manuscript-pdf","size":592778,"visible":true,"origin":"","legend":"","description":"","filename":"CIPPaperESPR.pdf","url":"https://assets-eu.researchsquare.com/files/rs-872896/v1_covered.pdf"}],"financialInterests":"","formattedTitle":"\u003cp\u003eUV Based Advanced Oxidation Process for Degradation of Ciprofloxacin: Reaction Kinetics, Effects of Interfering Substances and Degradation Product Identification\u003c/p\u003e","fulltext":[{"header":"Full Text","content":"This preprint is available for \u003ca href='/article/rs-872896/latest.pdf' target='_blank'\u003edownload as a PDF\u003c/a\u003e."}],"fulltextSource":"","fullText":"","funders":[],"hasAdminPriorityOnWorkflow":false,"hasManuscriptDocX":false,"hasOptedInToPreprint":true,"hasPassedJournalQc":"","hasAnyPriority":false,"hideJournal":true,"highlight":"","institution":"","isAcceptedByJournal":false,"isAuthorSuppliedPdf":true,"isDeskRejected":"","isHiddenFromSearch":false,"isInQc":false,"isInWorkflow":false,"isPdf":false,"isPdfUpToDate":true,"isWithdrawnOrRetracted":false,"journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true},"keywords":"Antibiotics, Ciprofloxacin, Degradation, Direct Photolysis, Scavenging effect, UV-H2O2","lastPublishedDoi":"10.21203/rs.3.rs-872896/v1","lastPublishedDoiUrl":"https://doi.org/10.21203/rs.3.rs-872896/v1","license":{"name":"CC BY 4.0","url":"https://creativecommons.org/licenses/by/4.0/"},"manuscriptAbstract":"\u003cp\u003eIn the photochemical UV-H\u003csub\u003e2\u003c/sub\u003eO\u003csub\u003e2 \u003c/sub\u003eadvanced oxidation process, H\u003csub\u003e2\u003c/sub\u003eO\u003csub\u003e2\u003c/sub\u003e absorbs UV light and is decomposed to form hydroxyl radicals (OH\u003csup\u003e\u003cstrong\u003e·\u003c/strong\u003e\u003c/sup\u003e), which are highly excited and reactive for electron-rich organic compounds and hence can degrade organic compounds. In the present work, the UV-H\u003csub\u003e2\u003c/sub\u003eO\u003csub\u003e2\u003c/sub\u003e process was investigated to degrade ciprofloxacin (CIP), one of India's widely used antibiotics, from aqueous solutions using a batch type UV reactor having photon flux = 1.9 (± 0.1) ×10\u003csup\u003e-4\u003c/sup\u003e Einstein L\u003csup\u003e-1\u003c/sup\u003e min\u003csup\u003e-1\u003c/sup\u003e. The effects of UV irradiation time on CIP degradation were investigated for both UV and UV-H\u003csub\u003e2\u003c/sub\u003eO\u003csub\u003e2\u003c/sub\u003e processes. It was found that about 75% degradation of CIP was achieved within 60 s with initial CIP concentration and peroxide concentration of 10 mg L\u003csup\u003e-1\u003c/sup\u003e and 1 mol H\u003csub\u003e2\u003c/sub\u003eO\u003csub\u003e2\u003c/sub\u003e/ mol CIP, respectively, at pH of 7(±0.1) and fluence dose of 113 mJ cm\u003csup\u003e-2\u003c/sup\u003e. The experimental data were analyzed by the first-order kinetics model to find out the time- and fluence-based degradation rate constants. Under optimized experimental conditions (initial CIP concentration, pH and H\u003csub\u003e2\u003c/sub\u003eO\u003csub\u003e2\u003c/sub\u003e dose of 10 mg L\u003csup\u003e-1\u003c/sup\u003e, 7(±0.1) and 1.0 mol H\u003csub\u003e2\u003c/sub\u003eO\u003csub\u003e2\u003c/sub\u003e / mol CIP, respectively), the fluence-based pseudo-first-order rate constant for the UV and UV-H\u003csub\u003e2\u003c/sub\u003eO\u003csub\u003e2\u003c/sub\u003e processes were determined to be 1.28(±0.0) ×10\u003csup\u003e-4\u003c/sup\u003e and 1.20(±0.04) ×10\u003csup\u003e-2\u003c/sup\u003e cm\u003csup\u003e2\u003c/sup\u003e mJ\u003csup\u003e-1\u003c/sup\u003e respectively.\u0026nbsp;The quantum yields at various pH under direct UV were calculated. The impacts of different process parameters such as H\u003csub\u003e2\u003c/sub\u003eO\u003csub\u003e2\u003c/sub\u003e concentration, solution pH, initial CIP concentration, and wastewater matrix on CIP degradation were also investigated in detail. CIP degradation was favorable in acidic conditions. Six degradation products of CIP were identified. Results clearly showed the potentiality of the UV-H\u003csub\u003e2\u003c/sub\u003eO\u003csub\u003e2\u003c/sub\u003e process for the degradation of antibiotics in wastewater.\u0026nbsp;\u0026nbsp;\u003c/p\u003e","manuscriptTitle":"UV Based Advanced Oxidation Process for Degradation of Ciprofloxacin: Reaction Kinetics, Effects of Interfering Substances and Degradation Product Identification","msid":"","msnumber":"","nonDraftVersions":[{"code":1,"date":"2021-12-06 17:43:48","doi":"10.21203/rs.3.rs-872896/v1","editorialEvents":[{"type":"communityComments","content":0}],"status":"published","journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true}}],"origin":"","ownerIdentity":"01222be3-c5b0-4f2e-91c3-982b38de8909","owner":[],"postedDate":"December 6th, 2021","published":true,"recentEditorialEvents":[],"rejectedJournal":[],"revision":"","amendment":"","status":"posted","subjectAreas":[{"id":8965555,"name":"Environmental Policy"}],"tags":[],"updatedAt":"2022-01-02T04:23:26+00:00","versionOfRecord":[],"versionCreatedAt":"2021-12-06 17:43:48","video":"","vorDoi":"","vorDoiUrl":"","workflowStages":[]},"version":"v1","identity":"rs-872896","journalConfig":"researchsquare"},"__N_SSP":true},"page":"/article/[identity]/[[...version]]","query":{"redirect":"/article/rs-872896","identity":"rs-872896","version":["v1"]},"buildId":"J0_U0BvcaRcwD8yVFaRlm","isFallback":false,"isExperimentalCompile":false,"dynamicIds":[84888],"gssp":true,"scriptLoader":[]}