Ozone and laser effects on dentin hypersensitivity treatment: a clinical study

Objectives: Evaluate and compare the clinical efficacy of diode laser and gas ozone in the treatment of dentin hypersensitivity (DHS) of non-carious-cervical lesion. Materials: and methods 88 teeth from 44 patients with moderate DHS were randomised into two groups according to a split-mouth design. In the diode laser group, the operator at first applicated the fluoride and potassium nitrate gel and then irradiated the superficial dentine exposed with 808 wavelength, incremental power from 0,2 to 0,6 W, with 20 seconds of interval. In the gas ozone group, the operator applicated, using a silicon cup, a high dose of ozone (32 g/m 3 ) for 30 seconds. The subjects underwent a first evaluation of the dentin sensitivity level (T0), directly after treatment (T1), after 3 months (T2), and after 6 months (T3), with a cold air blast challenge and tactile stimuli. The pain severity was quantified according to the Visual Analogue Scale (VAS). Statistical analysis was performed using Wilcoxon and Bonferroni correction for multiple comparisons (p=0.05). Results: A significant decrease of DHS were observed in both groups immediately, after 3 and 6 months of the therapy. After 6 months from the therapy, the sensitivity values in the teeth treated with gas ozone remain statistically lower than those treated with diode lasers (p=0.00026). Conclusion: Laser diode and gas ozone are both efficient as dentin sensitivity treatment. Ozone maintains an invariable effectiveness after 6 months. Clinical relevance Laser diode and gas ozone can be recommended to reduce dentinal hypersensitivities. Trial registration: ClinicalTrials.gov Identifier: NCT05853523