Protocol for a Cluster Randomized Trial To Evaluate The Effectiveness of Intervention On Myopia (The ES-SCI Study Intervention Section)

Background: Myopia is commonly observed among Chinese students aged 6-18 years. Objectives: To describe the protocol of the cluster-randomized trial to determine and evaluate the effectiveness and economic burden of multi-technology route intervention on myopia among eastern Chinese students. Methods: ： A cluster-randomized trial will be conducted to test the effectiveness of an intervention to prevent the progression or onset of myopia. The effectiveness evaluation will be tested in comparison with the control group. The participating students will be assessed at baseline and 3-,6-.9-.12-,24-,36-,48-,60-months follow up. Discussions: : Eastern Chinses Student common disease Surveillance Cohort and Intervention study is designed to provide accurate epidemiological clues and precise prevention strategies for school-age students. This study is a large sample and long-term follow-up cluster randomized controlled trial in eastern China. The intervention population is students aged 7.5-9.5. This study aims to provide an evidence-based basis for the intervention of myopia among Chinese students and provide the theoretical basis for the effect evaluation. Trial registration: ChiCTR2100051064. Registered on 11 Sep 2021.