Inactivated poliovirus vaccine induced Guillain–Barré syndrome: A Case Report

Abstract Guillain-Barré syndrome is a type of immune-mediated acute polyradiculoneuritis that is typically preceded by an unspecified infection. A 6-year-old black male preliminary school student who admitted to the pediatric ward with generalized body weakness comprising both lower and upper extremities (unable to move legs and hands as a usual motor movement), not walking alone without caregiver assistance, being unable to swallow food, blurred vision, tingling in the feet and hands, an irregular heartbeat, and severe muscular pain. The patient had quadriparesis, or muscle weakness, in all four limbs (both legs and arms). Motor examination revealed decreased muscle strength in all limbs, with a Medical Research Council score of 2/5 in the right arm of the upper extremities and 1/5 in the right leg of the lower extremities, and 1/5 in the left leg of the lower extremities and 2/5 in the left arm of the upper extremities. According to the clinical signs of Guillain-Barré syndrome, he received 400 mg/kg of intravenous immunoglobulin every day for five days.