Primary Amenorrhea due to Mayer–Rokitansky–Küster–Hauser (MRKH) Syndrome Managed with Laparoscopic Davydov Procedure: A Case Report

Primary Amenorrhea due to Mayer–Rokitansky–Küster–Hauser (MRKH) Syndrome Managed with Laparoscopic Davydov Procedure: A Case Report | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Case Report Primary Amenorrhea due to Mayer–Rokitansky–Küster–Hauser (MRKH) Syndrome Managed with Laparoscopic Davydov Procedure: A Case Report Rista Silvana, Kms. Yusuf Effendi, Amir Fauzi, Ratih Krisna This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-7339365/v1 This work is licensed under a CC BY 4.0 License Status: Posted Version 1 posted You are reading this latest preprint version Abstract Background: Mayer–Rokitansky–Küster–Hauser (MRKH) syndrome is a congenital anomaly characterized by uterovaginal aplasia in phenotypic females with normal secondary sexual characteristics. It is the second most common cause of primary amenorrhea and may require neovagina creation for sexual function. Laparoscopic Davydov vaginoplasty uses peritoneum to line a neovaginal canal, offering favorable outcomes. Case Presentation: A 19-year-old woman presented with primary amenorrhea and normal secondary sexual characteristics (Tanner P4M4). Examination revealed a ~3-cm vaginal dimple. Imaging showed uterine agenesis with normal ovaries. Laparoscopic Davydov procedure involved creation of a tract between bladder and rectum, mobilization of peritoneal flaps, pull-through to introitus, and cuff formation. Recovery was uneventful; follow-up showed good neovaginal length and tolerance of dilators. Conclusion: Laparoscopic Davydov vaginoplasty is a safe, effective option for MRKH, achieving satisfactory anatomy and function when combined with postoperative dilator use and counseling. MRKH syndrome primary amenorrhea Müllerian agenesis neovagina laparoscopic Davydov vaginoplasty Full Text Additional Declarations No competing interests reported. Supplementary Files FU1.png USG1.jpg USG2.jpg USG3.jpg Cite Share Download PDF Status: Posted Version 1 posted You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. 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It is the second most common cause of primary amenorrhea and may require neovagina creation for sexual function. Laparoscopic Davydov vaginoplasty uses peritoneum to line a neovaginal canal, offering favorable outcomes.\u0026nbsp;\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eCase Presentation:\u003c/strong\u003e A 19-year-old woman presented with primary amenorrhea and normal secondary sexual characteristics (Tanner P4M4). Examination revealed a ~3-cm vaginal dimple. Imaging showed uterine agenesis with normal ovaries. Laparoscopic Davydov procedure involved creation of a tract between bladder and rectum, mobilization of peritoneal flaps, pull-through to introitus, and cuff formation. 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