Clinical observation of Neiyi Xilie decoction treating dysmenorrhea caused by endometriosis

Objective:To evaluate the clinical curative effect of Neiyi Xilie (NYXL) decoction of Cai which treats EM patients with dysmenorrhea syndrome.Methods:Applied the non-randomly comparative method to compare the effectiveness of Neiyi Xilie decoction with the western medicine-Gestrinone treatment.It used the patients' ache integral,the TCM cor relative symptom integral,as effective treatment indicators.In the mean time,the study observed treatment progress when using Neiyi Xilie decoction toward PGF1α and TXB2 to briefly explore its function mechanism.Results:Clinically observed 74 patients with dysmenorrhea syndrome.Forty of them were in the treatment group.The total effective rate was 92.5%.The control group size was 34.Its total effective rate was 88.2%.There was no statistical significance between the two groups.This study concluded that Neiyi Xilie decoction was better than the control group in area of the TCM correlative symptom.The Neiyi Xilie decoction decreased the level of PGF1α and TXB2 significantly (P0.05).Conclusion:To summarize,it is significant for the clinical curative effect of Neiyi Xilie decoction to treat EM patients with dysmenorrhea syn drome.The Neiyi Xilie decoction can effectively reduce the pain of EM patients with dysmenorrheal and decrease the TCM correlative symptom integral.Its initial function mechanism may be related with the level of PGF1α and TXB2.