Endometrial stromal sarcoma resembling adenomyosis and menstrual-phase endometrium

Brunisholz Y, Y. Brunisholz, J. Miller, Miller J, J Scurry, James Scurry, Scurry J, Proietto A, A Proietto, Anthony Proietto
Gynecologic Oncology · 2004 · vol. 95(1) , pp. 256–259 · doi:10.1016/j.ygyno.2004.06.051 · PMID:15385142 · W2065083725
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This paper describes a case of endometrial stromal sarcoma that presented histologically and clinically with features mimicking adenomyosis and normal menstrual-phase endometrium.

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Abstract

BackgroundLow-grade endometrial stromal sarcoma (LGESS) and endometriosis are two conditions of different prognostic significance that are usually not difficult to distinguish histologically.CaseWe present the case of a 38-year-old woman who underwent laparotomy after a diagnosis of endometrial stromal neoplasm on uterine curettings. Uterine enlargement and regional and paraaortic lymphadenopathy were found. Pathology showed adenomyotic-like myometrial hypertrophy and menstrual-like shedding of tumor in involved lymph nodes. The finding of large areas of endometrial stromal cells without accompanying glands forming tumorous masses in both sites supported the diagnosis of LGESS. We believe that this is the first time that these phenomena have been reported in LGESS.ConclusionIn these cases, adenomyotic myometrial hypertrophy and menstrual shedding have been used to distinguish endometriosis from LGESS, but do not appear to be absolute criteria. Endometriosis and LGESS are undoubtedly separate entities, but occasionally may resemble each other.

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Condition tags

endometriosisadenomyosis

MeSH descriptors

Endometrial Neoplasms Endometriosis Sarcoma, Endometrial Stromal Adult Diagnosis, Differential Endometrial Neoplasms Endometrial Neoplasms Endometriosis Endometriosis Endometrium Endometrium Female Humans Lymph Nodes Lymph Nodes Menstruation Sarcoma, Endometrial Stromal Sarcoma, Endometrial Stromal

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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Cited by (2)

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