Quality and Reliability Assessment of Short Videos Related to Chronic Hepatitis B on TikTok and Bilibili

Quality and Reliability Assessment of Short Videos Related to Chronic Hepatitis B on TikTok and Bilibili | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Article Quality and Reliability Assessment of Short Videos Related to Chronic Hepatitis B on TikTok and Bilibili Yu Huang, Liwei Zeng, Yunfan Liu, Nana Cao, Zirui Chen, Yaqian Wen, and 3 more This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-8221754/v1 This work is licensed under a CC BY 4.0 License Status: Under Review Version 1 posted 7 You are reading this latest preprint version Abstract Background : Chronic hepatitis B (CHB) is a globally prevalent infectious liver disease. The scientific dissemination of knowledge on its prevention and treatment is crucial for reducing incidence, improving diagnosis and treatment rates, and eliminating social stigma. With the popularization of short video platforms, TikTok and Bilibili have become core channels for the Chinese public to obtain CHB-related information. However, systematic assessments of the quality and reliability of CHB-related short videos on these two platforms are still lacking. Methods : Using "乙肝" as the keyword, we searched and collected relevant science popularization short videos on TikTok and Bilibili. After strict screening, 149 valid samples were finally included (75 from TikTok and 74 from Bilibili). Three standardized tools—Global Quality Scale (GQS), Modified DISCERN, and Journal of the American Medical Association (JAMA)—were used to evaluate the information quality of the videos. Statistical techniques were employed to explore video characteristics and analyze the impacts of platform differences and video sources on content quality. Results : The overall quality of CHB-related short videos on TikTok and Bilibili was at a low level. The median (interquartile range) scores were 3 (2, 4) for GQS, 2 (1, 2) for Modified DISCERN, and 2 (1, 2) for JAMA. In platform comparison, TikTok had significantly higher scores than Bilibili in GQS (3 vs 3, P=0.009), Modified DISCERN (2 vs 1, P<0.001), and JAMA (2 vs 1, P<0.001). TikTok also showed advantages in interaction data (Likes, Comments, Favorites, Shares), number of followers, and creator certification rate. However, Bilibili had significantly longer video duration (200.5 vs 84 seconds, P<0.001). For video sources, videos uploaded by hepatology specialists had significantly higher scores in GQS (3 vs 2-3 points, P<0.001), Modified DISCERN (2 vs 1-1.75 points, P<0.001), and JAMA (2 vs 1-2 points, P<0.001) compared to those from other groups. Correlation analysis showed moderate to strong positive correlations between JAMA and GQS (r=0.6), JAMA and Modified DISCERN (r=0.48), and between GQS and Modified DISCERN (r=0.57). Moderate to very strong positive correlations were observed among Likes, Comments, Favorites, Shares, and number of followers (r=0.58-0.95), while interaction indicators had weak or no correlation with quality scores (r<0.4). Conclusion : The information quality and reliability of CHB-related short videos on TikTok and Bilibili are poor and need improvement. Platform attributes and uploaders' professional backgrounds may be key factors affecting video quality. It is recommended that short video platforms establish professional content review and recommendation mechanisms, and encourage hepatology professionals to participate in creating CHB-related science popularization content, so as to optimize the scientificity and accuracy of public access to CHB knowledge. Health sciences/Diseases Health sciences/Gastroenterology Health sciences/Health care Health sciences/Medical research Chronic hepatitis B TikTok Bilibili Short videos Information quality Reliability Full Text Additional Declarations No competing interests reported. Cite Share Download PDF Status: Under Review Version 1 posted Reviews received at journal 20 Apr, 2026 Reviewers agreed at journal 10 Apr, 2026 Reviewers invited by journal 03 Apr, 2026 Editor invited by journal 04 Dec, 2025 Editor assigned by journal 28 Nov, 2025 Submission checks completed at journal 28 Nov, 2025 First submitted to journal 27 Nov, 2025 You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. Our growing team is made up of researchers and industry professionals working together to solve the most critical problems facing scientific publishing. Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-8221754","acceptedTermsAndConditions":true,"allowDirectSubmit":false,"archivedVersions":[],"articleType":"Article","associatedPublications":[],"authors":[{"id":619878433,"identity":"42f03912-9ea8-4e40-a550-ae4b4d5c1164","order_by":0,"name":"Yu Huang","email":"","orcid":"","institution":"","correspondingAuthor":false,"prefix":"","firstName":"Yu","middleName":"","lastName":"Huang","suffix":""},{"id":619878436,"identity":"909412f1-c8c0-4854-bec0-069dd9d35a43","order_by":1,"name":"Liwei 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Bilibili, Short videos, Information quality, Reliability","lastPublishedDoi":"10.21203/rs.3.rs-8221754/v1","lastPublishedDoiUrl":"https://doi.org/10.21203/rs.3.rs-8221754/v1","license":{"name":"CC BY 4.0","url":"https://creativecommons.org/licenses/by/4.0/"},"manuscriptAbstract":"\u003cp\u003e\u003cstrong\u003eBackground\u003c/strong\u003e: Chronic hepatitis B (CHB) is a globally prevalent infectious liver disease. The scientific dissemination of knowledge on its prevention and treatment is crucial for reducing incidence, improving diagnosis and treatment rates, and eliminating social stigma. With the popularization of short video platforms, TikTok and Bilibili have become core channels for the Chinese public to obtain CHB-related information. However, systematic assessments of the quality and reliability of CHB-related short videos on these two platforms are still lacking.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eMethods\u003c/strong\u003e: Using \"乙肝\" as the keyword, we searched and collected relevant science popularization short videos on TikTok and Bilibili. After strict screening, 149 valid samples were finally included (75 from TikTok and 74 from Bilibili). Three standardized tools—Global Quality Scale (GQS), Modified DISCERN, and Journal of the American Medical Association (JAMA)—were used to evaluate the information quality of the videos. Statistical techniques were employed to explore video characteristics and analyze the impacts of platform differences and video sources on content quality.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eResults\u003c/strong\u003e: The overall quality of CHB-related short videos on TikTok and Bilibili was at a low level. The median (interquartile range) scores were 3 (2, 4) for GQS, 2 (1, 2) for Modified DISCERN, and 2 (1, 2) for JAMA. In platform comparison, TikTok had significantly higher scores than Bilibili in GQS (3 vs 3, P=0.009), Modified DISCERN (2 vs 1, P\u0026lt;0.001), and JAMA (2 vs 1, P\u0026lt;0.001). TikTok also showed advantages in interaction data (Likes, Comments, Favorites, Shares), number of followers, and creator certification rate. However, Bilibili had significantly longer video duration (200.5 vs 84 seconds, P\u0026lt;0.001). For video sources, videos uploaded by hepatology specialists had significantly higher scores in GQS (3 vs 2-3 points, P\u0026lt;0.001), Modified DISCERN (2 vs 1-1.75 points, P\u0026lt;0.001), and JAMA (2 vs 1-2 points, P\u0026lt;0.001) compared to those from other groups. Correlation analysis showed moderate to strong positive correlations between JAMA and GQS (r=0.6), JAMA and Modified DISCERN (r=0.48), and between GQS and Modified DISCERN (r=0.57). Moderate to very strong positive correlations were observed among Likes, Comments, Favorites, Shares, and number of followers (r=0.58-0.95), while interaction indicators had weak or no correlation with quality scores (r\u0026lt;0.4).\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eConclusion\u003c/strong\u003e: The information quality and reliability of CHB-related short videos on TikTok and Bilibili are poor and need improvement. Platform attributes and uploaders' professional backgrounds may be key factors affecting video quality. It is recommended that short video platforms establish professional content review and recommendation mechanisms, and encourage hepatology professionals to participate in creating CHB-related science popularization content, so as to optimize the scientificity and accuracy of public access to CHB knowledge.\u003c/p\u003e","manuscriptTitle":"Quality and Reliability Assessment of Short Videos Related to Chronic Hepatitis B on TikTok and Bilibili","msid":"","msnumber":"","nonDraftVersions":[{"code":1,"date":"2026-04-09 20:24:58","doi":"10.21203/rs.3.rs-8221754/v1","editorialEvents":[{"type":"communityComments","content":0},{"type":"editorInvitedReview","content":"","date":"2026-04-20T18:00:43+00:00","index":"hide","fulltext":""},{"type":"reviewerAgreed","content":"273712695569667686613681241088825540488","date":"2026-04-10T19:38:54+00:00","index":"hide","fulltext":""},{"type":"reviewersInvited","content":"","date":"2026-04-03T07:50:42+00:00","index":"","fulltext":""},{"type":"editorInvited","content":"","date":"2025-12-04T08:57:17+00:00","index":"","fulltext":""},{"type":"editorAssigned","content":"","date":"2025-11-28T05:44:37+00:00","index":"","fulltext":""},{"type":"checksComplete","content":"","date":"2025-11-28T05:42:43+00:00","index":"","fulltext":""},{"type":"submitted","content":"Scientific Reports","date":"2025-11-27T11:48:14+00:00","index":"","fulltext":""}],"status":"published","journal":{"display":true,"email":"[email protected]","identity":"scientific-reports","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":false,"externalIdentity":"scirep","sideBox":"Learn more about [Scientific Reports](http://www.nature.com/srep/)","snPcode":"","submissionUrl":"","title":"Scientific Reports","twitterHandle":"","acdcEnabled":true,"dfaEnabled":true,"editorialSystem":"stoa","reportingPortfolio":"Scientific Reports","inReviewEnabled":true,"inReviewRevisionsEnabled":true}}],"origin":"","ownerIdentity":"fd57f75b-25d2-4045-8915-8ba773556153","owner":[],"postedDate":"April 9th, 2026","published":true,"recentEditorialEvents":[],"rejectedJournal":[],"revision":"","amendment":"","status":"under-review","subjectAreas":[{"id":65968326,"name":"Health sciences/Diseases"},{"id":65968327,"name":"Health sciences/Gastroenterology"},{"id":65968328,"name":"Health sciences/Health care"},{"id":65968329,"name":"Health sciences/Medical research"}],"tags":[],"updatedAt":"2026-04-09T20:24:58+00:00","versionOfRecord":[],"versionCreatedAt":"2026-04-09 20:24:58","video":"","vorDoi":"","vorDoiUrl":"","workflowStages":[]},"version":"v1","identity":"rs-8221754","journalConfig":"researchsquare"},"__N_SSP":true},"page":"/article/[identity]/[[...version]]","query":{"redirect":"/article/rs-8221754","identity":"rs-8221754","version":["v1"]},"buildId":"XKTyCvWXoU3ODBz1xrDgd","isFallback":false,"isExperimentalCompile":false,"dynamicIds":[84888],"gssp":true,"scriptLoader":[]}