Inhibition Efficacy of Expired Citalopram Drug Towards the Damage of C-steel in Hydrochloric Acid Solution

Inhibition Efficacy of Expired Citalopram Drug Towards the Damage of C-steel in Hydrochloric Acid Solution | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Article Inhibition Efficacy of Expired Citalopram Drug Towards the Damage of C-steel in Hydrochloric Acid Solution Mahmoud G.A. Saleh, Rasha N. Felaly, H. Hawsawi, Salih S. Al-Juaid, and 4 more This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-7973994/v1 This work is licensed under a CC BY 4.0 License Status: Published Journal Publication published 04 Apr, 2026 Read the published version in Scientific Reports → Version 1 posted 13 You are reading this latest preprint version Abstract The effectiveness of expired citalopram (Cp) as a corrosion inhibitor for C-steel in hydrochloric acid solution was investigated. Chemical and electrochemical measurements were utilized. The damage rate was reduced with an increasing concentration of the Cp compound. The protective performance is improved with increasing concentrations of Cp, achieving efficiency levels above 92.0% at 0.005 M and 25°C. The inhibition mechanism was attributed to the adsorption of Cp molecules onto the steel surface. The negative values of ΔG° indicate that the adsorption of Cp molecules occurs spontaneously. Depending on the solution temperature, the Δ G o ads lie between − 36.16 and − 33.72 kJ/mol, emphasizing the physicochemical sorption process. The decline in K ads values at elevated temperatures is ascribed to the desorption of Cp inhibitor species from the carbon steel surface into the solution. The high absorption energy values would suggest good protection properties of the Cp compound. Physical sciences/Chemistry Physical sciences/Materials science Citalopram drug H2 Production Impedance Gravimetry Potentiodynamic polarization Inhibition Full Text Additional Declarations No competing interests reported. Cite Share Download PDF Status: Published Journal Publication published 04 Apr, 2026 Read the published version in Scientific Reports → Version 1 posted Editorial decision: Revision requested 17 Nov, 2025 Reviews received at journal 14 Nov, 2025 Reviews received at journal 13 Nov, 2025 Reviewers agreed at journal 11 Nov, 2025 Reviewers agreed at journal 11 Nov, 2025 Reviews received at journal 11 Nov, 2025 Reviewers agreed at journal 11 Nov, 2025 Reviewers agreed at journal 11 Nov, 2025 Reviewers invited by journal 11 Nov, 2025 Editor assigned by journal 10 Nov, 2025 Editor invited by journal 09 Nov, 2025 Submission checks completed at journal 06 Nov, 2025 First submitted to journal 06 Nov, 2025 You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. Our growing team is made up of researchers and industry professionals working together to solve the most critical problems facing scientific publishing. Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-7973994","acceptedTermsAndConditions":true,"allowDirectSubmit":false,"archivedVersions":[],"articleType":"Article","associatedPublications":[],"authors":[{"id":546151159,"identity":"1f6931ad-6e21-4b93-9400-8c11d632d4b0","order_by":0,"name":"Mahmoud G.A. 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Solution","fulltext":[],"fulltextSource":"","fullText":"","funders":[],"hasAdminPriorityOnWorkflow":false,"hasManuscriptDocX":false,"hasOptedInToPreprint":true,"hasPassedJournalQc":"","hasAnyPriority":false,"hideJournal":false,"highlight":"","institution":"","isAcceptedByJournal":true,"isAuthorSuppliedPdf":true,"isDeskRejected":"","isHiddenFromSearch":false,"isInQc":false,"isInWorkflow":false,"isPdf":true,"isPdfUpToDate":true,"isWithdrawnOrRetracted":false,"journal":{"display":true,"email":"[email protected]","identity":"scientific-reports","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":false,"externalIdentity":"scirep","sideBox":"Learn more about [Scientific Reports](http://www.nature.com/srep/)","snPcode":"","submissionUrl":"","title":"Scientific Reports","twitterHandle":"","acdcEnabled":true,"dfaEnabled":true,"editorialSystem":"stoa","reportingPortfolio":"Scientific Reports","inReviewEnabled":true,"inReviewRevisionsEnabled":true},"keywords":"Citalopram drug, H2 Production, Impedance, Gravimetry, Potentiodynamic polarization, Inhibition","lastPublishedDoi":"10.21203/rs.3.rs-7973994/v1","lastPublishedDoiUrl":"https://doi.org/10.21203/rs.3.rs-7973994/v1","license":{"name":"CC BY 4.0","url":"https://creativecommons.org/licenses/by/4.0/"},"manuscriptAbstract":"\u003cp\u003eThe effectiveness of expired citalopram (Cp) as a corrosion inhibitor for C-steel in hydrochloric acid solution was investigated. Chemical and electrochemical measurements were utilized. The damage rate was reduced with an increasing concentration of the Cp compound. The protective performance is improved with increasing concentrations of Cp, achieving efficiency levels above 92.0% at 0.005 M and 25\u0026deg;C. The inhibition mechanism was attributed to the adsorption of Cp molecules onto the steel surface. The negative values of ΔG\u0026deg; indicate that the adsorption of Cp molecules occurs spontaneously. Depending on the solution temperature, the Δ\u003cem\u003eG\u003c/em\u003e\u003csup\u003eo\u003c/sup\u003e\u003csub\u003eads\u003c/sub\u003e lie between \u0026minus;\u0026thinsp;36.16 and \u0026minus;\u0026thinsp;33.72 kJ/mol, emphasizing the physicochemical sorption process. The decline in K\u003csub\u003e\u003cem\u003eads\u003c/em\u003e\u003c/sub\u003e values at elevated temperatures is ascribed to the desorption of Cp inhibitor species from the carbon steel surface into the solution. The high absorption energy values would suggest good protection properties of the Cp compound.\u003c/p\u003e","manuscriptTitle":"Inhibition Efficacy of Expired Citalopram Drug Towards the Damage of C-steel in Hydrochloric Acid Solution","msid":"","msnumber":"","nonDraftVersions":[{"code":1,"date":"2025-11-20 13:49:06","doi":"10.21203/rs.3.rs-7973994/v1","editorialEvents":[{"type":"communityComments","content":0},{"type":"decision","content":"Revision requested","date":"2025-11-17T09:15:25+00:00","index":"","fulltext":""},{"type":"editorInvitedReview","content":"","date":"2025-11-14T12:12:09+00:00","index":"hide","fulltext":""},{"type":"editorInvitedReview","content":"","date":"2025-11-14T01:35:43+00:00","index":"hide","fulltext":""},{"type":"reviewerAgreed","content":"268412068619644606704864511641820456284","date":"2025-11-12T01:14:07+00:00","index":"hide","fulltext":""},{"type":"reviewerAgreed","content":"118522661226828276117600572986936629375","date":"2025-11-11T17:01:03+00:00","index":"hide","fulltext":""},{"type":"editorInvitedReview","content":"","date":"2025-11-11T13:16:35+00:00","index":"hide","fulltext":""},{"type":"reviewerAgreed","content":"47633513796601115755995568726367706329","date":"2025-11-11T12:56:22+00:00","index":"hide","fulltext":""},{"type":"reviewerAgreed","content":"160325882242979728029472565342895020564","date":"2025-11-11T11:16:52+00:00","index":"hide","fulltext":""},{"type":"reviewersInvited","content":"","date":"2025-11-11T09:59:31+00:00","index":"","fulltext":""},{"type":"editorAssigned","content":"","date":"2025-11-10T05:40:43+00:00","index":"","fulltext":""},{"type":"editorInvited","content":"","date":"2025-11-10T04:23:10+00:00","index":"","fulltext":""},{"type":"checksComplete","content":"","date":"2025-11-06T22:22:37+00:00","index":"","fulltext":""},{"type":"submitted","content":"Scientific Reports","date":"2025-11-06T22:18:59+00:00","index":"","fulltext":""}],"status":"published","journal":{"display":true,"email":"[email protected]","identity":"scientific-reports","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":false,"externalIdentity":"scirep","sideBox":"Learn more about [Scientific Reports](http://www.nature.com/srep/)","snPcode":"","submissionUrl":"","title":"Scientific Reports","twitterHandle":"","acdcEnabled":true,"dfaEnabled":true,"editorialSystem":"stoa","reportingPortfolio":"Scientific Reports","inReviewEnabled":true,"inReviewRevisionsEnabled":true}}],"origin":"","ownerIdentity":"c8a75989-add3-4b6b-9cf5-e822b6ce5339","owner":[],"postedDate":"November 20th, 2025","published":true,"recentEditorialEvents":[],"rejectedJournal":[],"revision":"","amendment":"","status":"published-in-journal","subjectAreas":[{"id":58096758,"name":"Physical sciences/Chemistry"},{"id":58096759,"name":"Physical sciences/Materials science"}],"tags":[],"updatedAt":"2026-04-07T16:07:00+00:00","versionOfRecord":{"articleIdentity":"rs-7973994","link":"https://doi.org/10.1038/s41598-026-40754-6","journal":{"identity":"scientific-reports","isVorOnly":false,"title":"Scientific Reports"},"publishedOn":"2026-04-04 15:59:12","publishedOnDateReadable":"April 4th, 2026"},"versionCreatedAt":"2025-11-20 13:49:06","video":"","vorDoi":"10.1038/s41598-026-40754-6","vorDoiUrl":"https://doi.org/10.1038/s41598-026-40754-6","workflowStages":[]},"version":"v1","identity":"rs-7973994","journalConfig":"researchsquare"},"__N_SSP":true},"page":"/article/[identity]/[[...version]]","query":{"redirect":"/article/rs-7973994","identity":"rs-7973994","version":["v1"]},"buildId":"XKTyCvWXoU3ODBz1xrDgd","isFallback":false,"isExperimentalCompile":false,"dynamicIds":[84888],"gssp":true,"scriptLoader":[]}