Clinical study of levonorgestrel-releasing intrauterine system in the treatment of adenomyosis

Objective To investigate the clinical efficacy of levonorgestrel-releasing intrauterine system(LNG-IUS) in the treatment of adenomyosis.Methods Thirty eight patients with adenomyosis were followed up in 0,1,3,6 months after treating with LNG-IUS.The menstrual blood volume,dysmenorrheal,size of ulteri and endometrial thickness were observed and evaluated.Results After inserting LNG-IUS,dysmenorrhea was obviously alleviated,and the dysmenorrheal scores decreased to(22±7) from(75±15)(P0.05).The menstrual blood volume by PBAC were(197±65),(53±22),(42±13) and(25±13) in 0,1,3,6 months after the insertion.Endometrial thickness reduced significantly in 6 months,and the size of uteri didn't change significantly.Conclusion LIG-IUS is an effective and safe therapy for adenomyosis.