Unscheduled bleeding in continuous combined hormone therapy users

Martha Hickey, Devini Ameratunga, Jennifer L. Marino
Maturitas · 2011 · vol. 70(4) , pp. 400–403 · doi:10.1016/j.maturitas.2011.09.010 · PMID:22030385 · W2033890374
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This study investigated the incidence and risk factors associated with unscheduled bleeding in women using continuous combined hormone therapy.

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Abstract

Continuous combined hormone therapy (HT) is effective for menopausal vasomotor symptoms and vaginal dryness but commonly leads to unscheduled vaginal bleeding and spotting. Unscheduled bleeding is disliked by women and may lead to invasive investigations to exclude underlying pelvic pathology. In most cases investigations do not reveal any underlying cause for the bleeding.

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MeSH descriptors

Endometrium Estrogen Replacement Therapy Progestins Uterine Hemorrhage Endometrium Endometrium Endometrium Estrogen Replacement Therapy Female Humans Postmenopause Progestins Ultrasonography Uterine Hemorrhage Uterine Hemorrhage Uterine Hemorrhage

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