Predeposit Autologous Blood Transfusion in Simple Total Hysterectomy for Uterine Myoma or Endometriosis

TAKASHI YAMADA, Hirosumi IMOTO, Minoru Ueki
In: Bulletin of the Osaka Medical College · 1997 · vol. 43(2) , pp. 13–17 · W7145134692
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⚙ AI-generated summary by claude@2026-06, 2026-06-13 ⓘ

This study compared two EPO administration methods and evaluated predeposit autologous blood transfusion (PAT) in hysterectomy patients, finding PAT effective and safe with no significant difference between EPO methods.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-13 · read from full text ⓘ

The paper examined two methods of erythropoietin (EPO) administration and evaluated the effectiveness and safety of predeposit autologous blood transfusion (PAT) in patients with uterine myoma or endometriosis undergoing simple total hysterectomy. Eighteen patients received EPO by either subcutaneous or intravenous injection over a period enabling predeposit of 800 mL of blood across 2 weeks, with hemoglobin (Hb) and platelet (PLT) monitored and PAT side effects assessed. There was no statistical difference between the two EPO routes in Hb/PLT changes, and in one patient with 1,125 mL bleeding, reinfusion of the predeposited 800 mL was effective; no PAT-related side effects were observed during the predeposit-to-reinfusion period. The study explicitly notes a limitation of a small number of patients. This paper is centrally about endometriosis — it reports PAT effectiveness and safety in patients with uterine endometriosis undergoing simple total hysterectomy, alongside comparisons of EPO administration routes.

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Abstract

The effects of two kinds of erythropoietin (EPO), and the effectiveness and safety of predeposit autologous blood transfusion (PAT) were examined in patients with uterine myoma or endometriosis who underwent simple total hysterectomy. EPO was administered to all the patients 18 cases for enhancement of hemopoietic function by two different methods, subcutaneous injection and intravenous injection, and their effects were compared (t test). Predeposition of 800 ml of blood was performed over 2 weeks and hemoglobin (Hb) and platelet (PLT) values monitored. The presence and absence of side-effects of PAT were also examined. There was no statistical difference between the two types of EPO in their effect on changes in the Hb and PLT values. In the 18 cases, one patient exhibited bleeding of 1,125 ml and reinfusion of the predeposited blood (800 ml) proved to be effective. None of the patients showed side effects during the period from predeposition to reinfusion. There was no difference between the two kinds of EPO for hemopoietic effect. Despite the limited number of patients examined, the present study confirmed the effectiveness and safety of PAT in combination with administration of EPO for operations of benign diseases.
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WEKO3 アイテム Predeposit Autologous Blood Transfusion in Simple Total Hysterectomy for Uterine Myoma or Endometriosis https://ompu.repo.nii.ac.jp/records/2000161 https://ompu.repo.nii.ac.jp/records/20001615560d74d-57fd-4fd4-9aea-9547bd0309cd | 名前 / ファイル | ライセンス | アクション | |---|---|---| | 43_2_02_yamada.pdf (4.9 MB) | | アイテムタイプ | 紀要論文 / Departmental Bulletin Paper(1) | ||||||||||| |---|---|---|---|---|---|---|---|---|---|---|---|---| | 公開日 | 2024-05-28 | ||||||||||| | タイトル | |||||||||||| | タイトル | Predeposit Autologous Blood Transfusion in Simple Total Hysterectomy for Uterine Myoma or Endometriosis | ||||||||||| | 言語 | en | ||||||||||| | 言語 | |||||||||||| | 言語 | eng | ||||||||||| | 資源タイプ | |||||||||||| | 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | ||||||||||| | 資源タイプ | departmental bulletin paper | ||||||||||| | アクセス権 | |||||||||||| | アクセス権 | open access | ||||||||||| | アクセス権URI | http://purl.org/coar/access_right/c_abf2 | ||||||||||| | 著者 | Takashi YAMADA × Takashi YAMADA × Hirosumi IMOTO × Minoru UEKI | ||||||||||| | 抄録 | |||||||||||| | 内容記述タイプ | Abstract | ||||||||||| | 内容記述 | The effects of two kinds of erythropoietin (EPO), and the effectiveness and safety of predeposit autologous blood transfusion (PAT) were examined in patients with uterine myoma or endometriosis who underwent simple total hysterectomy. EPO was administered to all the patients 18 cases for enhancement of hemopoietic function by two different methods, subcutaneous injection and intravenous injection, and their effects were compared (t test). Predeposition of 800 ml of blood was performed over 2 weeks and hemoglobin (Hb) and platelet (PLT) values monitored. The presence and absence of side-effects of PAT were also examined. There was no statistical difference between the two types of EPO in their effect on changes in the Hb and PLT values. In the 18 cases, one patient exhibited bleeding of 1,125 ml and reinfusion of the predeposited blood (800 ml) proved to be effective. None of the patients showed side effects during the period from predeposition to reinfusion. There was no difference between the two kinds of EPO for hemopoietic effect. Despite the limited number of patients examined, the present study confirmed the effectiveness and safety of PAT in combination with administration of EPO for operations of benign diseases. | ||||||||||| | 言語 | en | ||||||||||| | 書誌情報 | en : Bulletin of the Osaka Medical College 巻 43, 号 2, p. 13-17, 発行日 1997-12 | ||||||||||| | 出版者 | |||||||||||| | 出版者 | Osaka Medical College | ||||||||||| | 言語 | en | ||||||||||| | ISSN | |||||||||||| | 収録物識別子タイプ | ISSN | ||||||||||| | 収録物識別子 | 0916-2844 |

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